PDB entry 7efp

View 7efp on RCSB PDB site
Description: Structure of SARS-CoV-2 spike receptor-binding domain in complex with high affinity ACE2 mutant (S19W,N330Y)
Class: viral protein
Keywords: receptor-binding domain, angiotensin converting enzyme 2, VIRAL PROTEIN
Deposited on 2021-03-22, released 2021-11-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-11-24, with a file datestamp of 2021-11-19.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Processed angiotensin-converting enzyme 2
    Species: Homo sapiens [TaxId:9606]
    Gene: ACE2, UNQ868/PRO1885
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9BYF1 (2-598)
      • expression tag (0-1)
      • engineered mutation (2)
      • engineered mutation (313)
    Domains in SCOPe 2.08: d7efpa_
  • Chain 'B':
    Compound: Spike glycoprotein
    Species: Severe acute respiratory syndrome coronavirus 2 [TaxId:2697049]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7efpb_
  • Heterogens: NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7efpA (A:)
adwtieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeq
stlaqmyplqeiqnltvklqlqalqqngssvlsedkskrlntilntmstiystgkvcnpd
npqeclllepglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhy
edygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyi
spigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffv
svglpnmtqgfweysmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhem
ghiqydmayaaqpfllrnganegfheavgeimslsaatpkhlksigllspdfqednetei
nfllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdet
ycdpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfn
mlrlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnknsfvgwstdwspyad

    Sequence, based on observed residues (ATOM records): (download) 
    >7efpA (A:)
wtieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqst
laqmyplqeiqnltvklqlqalqqngssvlsedkskrlntilntmstiystgkvcnpdnp
qeclllepglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyed
ygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyisp
igclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsv
glpnmtqgfweysmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemgh
iqydmayaaqpfllrnganegfheavgeimslsaatpkhlksigllspdfqedneteinf
llkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetyc
dpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnml
rlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnknsfvgwstdwspya

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >7efpB (B:)
vqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkc
ygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsn
nldskvggnynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqp
tngvgyqpyrvvvlsfellhapatvcgpkkstnlvknk

    Sequence, based on observed residues (ATOM records): (download) 
    >7efpB (B:)
nlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcft
nvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvggnynyly
rlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyqpyrvvvl
sfellhapatvcgp