PDB entry 6cu3

View 6cu3 on RCSB PDB site
Description: Crystal structure of a protein arginine N-methyltransferase from Naegleria fowleri
Class: transferase
Keywords: NIAID, structural genomics, SAM, SAH, Seattle Structural Genomics Center for Infectious Disease, SSGCID, TRANSFERASE
Deposited on 2018-03-23, released 2018-04-04
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-04-04, with a file datestamp of 2018-03-29.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: protein arginine N-methyltransferase
    Species: Naegleria fowleri [TaxId:5763]
    Database cross-references and differences (RAF-indexed):
    • PDB 6CU3 (Start-335)
    Domains in SCOPe 2.07: d6cu3a_
  • Chain 'B':
    Compound: protein arginine N-methyltransferase
    Species: Naegleria fowleri [TaxId:5763]
    Database cross-references and differences (RAF-indexed):
    • PDB 6CU3 (Start-335)
    Domains in SCOPe 2.07: d6cu3b_
  • Chain 'C':
    Compound: protein arginine N-methyltransferase
    Species: Naegleria fowleri [TaxId:5763]
    Database cross-references and differences (RAF-indexed):
    • PDB 6CU3 (Start-335)
    Domains in SCOPe 2.07: d6cu3c_
  • Chain 'D':
    Compound: protein arginine N-methyltransferase
    Species: Naegleria fowleri [TaxId:5763]
    Database cross-references and differences (RAF-indexed):
    • PDB 6CU3 (Start-335)
    Domains in SCOPe 2.07: d6cu3d_
  • Chain 'E':
    Compound: protein arginine N-methyltransferase
    Species: Naegleria fowleri [TaxId:5763]
    Database cross-references and differences (RAF-indexed):
    • PDB 6CU3 (Start-335)
    Domains in SCOPe 2.07: d6cu3e_
  • Chain 'F':
    Compound: protein arginine N-methyltransferase
    Species: Naegleria fowleri [TaxId:5763]
    Database cross-references and differences (RAF-indexed):
    • PDB 6CU3 (Start-335)
    Domains in SCOPe 2.07: d6cu3f_
  • Heterogens: EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6cu3A (A:)
mahhhhhhmndfhhdfqqqqpttgiheemlkdgirtnayknailqnkhlfkdkvvldigc
gtgilclfaakagakrvigidmsdiidkarqivsdngyshvielikgkvediaqlpfgie
kvdiiisewmgyfllyesmlqtvlsardrwlrpggylfpdkctmyicgiedseykrdkid
fwdnvygfnfsaikadalreplvdfvesqqiittqskfleidlntiqpedlkqittsfef
tsqyqeycqafvawfdcvfsrgphkpvefstgpftegthwkqtvfylendlplkpndvik
gtitisqnksnhrdldismkytvnggavisqdyimr

    Sequence, based on observed residues (ATOM records): (download) 
    >6cu3A (A:)
heemlkdgirtnayknailqnkhlfkdkvvldigcgtgilclfaakagakrvigidmsdi
idkarqivsdngyshvielikgkvediaqlpfgiekvdiiisewmgyfllyesmlqtvls
ardrwlrpggylfpdkctmyicgiedseykrdkidfwdnvygfnfsaikadalreplvdf
vesqqiittqskfleidlntiqpedlkqittsfeftsqyqeycqafvawfdcvfsrgphk
pvefstgpftegthwkqtvfylendlplkpndvikgtitisqnksnhrdldismkytvng
gavisqdyimr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6cu3B (B:)
mahhhhhhmndfhhdfqqqqpttgiheemlkdgirtnayknailqnkhlfkdkvvldigc
gtgilclfaakagakrvigidmsdiidkarqivsdngyshvielikgkvediaqlpfgie
kvdiiisewmgyfllyesmlqtvlsardrwlrpggylfpdkctmyicgiedseykrdkid
fwdnvygfnfsaikadalreplvdfvesqqiittqskfleidlntiqpedlkqittsfef
tsqyqeycqafvawfdcvfsrgphkpvefstgpftegthwkqtvfylendlplkpndvik
gtitisqnksnhrdldismkytvnggavisqdyimr

    Sequence, based on observed residues (ATOM records): (download) 
    >6cu3B (B:)
iheemlkdgirtnayknailqnkhlfkdkvvldigcgtgilclfaakagakrvigidmsd
iidkarqivsdngyshvielikgkvediaqlpfgiekvdiiisewmgyfllyesmlqtvl
sardrwlrpggylfpdkctmyicgiedseykrdkidfwdnvygfnfsaikadalreplvd
fvesqqiittqskfleidlntiqpedlkqittsfeftsqyqeycqafvawfdcvfsrgph
kpvefstgpftegthwkqtvfylendlplkpndvikgtitisqnksnhrdldismkytvn
ggavisqdyimr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6cu3C (C:)
mahhhhhhmndfhhdfqqqqpttgiheemlkdgirtnayknailqnkhlfkdkvvldigc
gtgilclfaakagakrvigidmsdiidkarqivsdngyshvielikgkvediaqlpfgie
kvdiiisewmgyfllyesmlqtvlsardrwlrpggylfpdkctmyicgiedseykrdkid
fwdnvygfnfsaikadalreplvdfvesqqiittqskfleidlntiqpedlkqittsfef
tsqyqeycqafvawfdcvfsrgphkpvefstgpftegthwkqtvfylendlplkpndvik
gtitisqnksnhrdldismkytvnggavisqdyimr

    Sequence, based on observed residues (ATOM records): (download) 
    >6cu3C (C:)
eemlkdgirtnayknailqnkhlfkdkvvldigcgtgilclfaakagakrvigidmsdii
dkarqivsdngyshvielikgkvediaqlpfgiekvdiiisewmgyfllyesmlqtvlsa
rdrwlrpggylfpdkctmyicgiedseykrdkidfwdnvygfnfsaikadalreplvdfv
esqqiittqskfleidlntiqpedlkqittsfeftsqyqeycqafvawfdcvfskpvefs
tgpftegthwkqtvfylendlplkpndvikgtitisqnksnhrdldismkytvnggavis
qdyimr

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6cu3D (D:)
mahhhhhhmndfhhdfqqqqpttgiheemlkdgirtnayknailqnkhlfkdkvvldigc
gtgilclfaakagakrvigidmsdiidkarqivsdngyshvielikgkvediaqlpfgie
kvdiiisewmgyfllyesmlqtvlsardrwlrpggylfpdkctmyicgiedseykrdkid
fwdnvygfnfsaikadalreplvdfvesqqiittqskfleidlntiqpedlkqittsfef
tsqyqeycqafvawfdcvfsrgphkpvefstgpftegthwkqtvfylendlplkpndvik
gtitisqnksnhrdldismkytvnggavisqdyimr

    Sequence, based on observed residues (ATOM records): (download) 
    >6cu3D (D:)
heemlkdgirtnayknailqnkhlfkdkvvldigcgtgilclfaakagakrvigidmsdi
idkarqivsdngyshvielikgkvediaqlpfgiekvdiiisewmgyfllyesmlqtvls
ardrwlrpggylfpdkctmyicgiedseykrdkidfwdnvygfnfsaikadalreplvdf
vesqqiittqskfleidlntiqpedlkqittsfeftsqyqeycqafvawfdcvfsrgphk
pvefstgpftegthwkqtvfylendlplkpndvikgtitisqnksnhrdldismkytvng
gavisqdyimr

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6cu3E (E:)
mahhhhhhmndfhhdfqqqqpttgiheemlkdgirtnayknailqnkhlfkdkvvldigc
gtgilclfaakagakrvigidmsdiidkarqivsdngyshvielikgkvediaqlpfgie
kvdiiisewmgyfllyesmlqtvlsardrwlrpggylfpdkctmyicgiedseykrdkid
fwdnvygfnfsaikadalreplvdfvesqqiittqskfleidlntiqpedlkqittsfef
tsqyqeycqafvawfdcvfsrgphkpvefstgpftegthwkqtvfylendlplkpndvik
gtitisqnksnhrdldismkytvnggavisqdyimr

    Sequence, based on observed residues (ATOM records): (download) 
    >6cu3E (E:)
emlkdgirtnayknailqnkhlfkdkvvldigcgtgilclfaakagakrvigidmsdiid
karqivsdngyshvielikgkvediaqlpfgiekvdiiisewmgyfllyesmlqtvlsar
drwlrpggylfpdkctmyicgiedseykrdkidfwdnvygfnfsaikadalreplvdfve
sqqiittqskfleidlntiqpedlkqittsfeftsqyqeycqafvawfdcvfsrgphkpv
efstgpftegthwkqtvfylendlplkpndvikgtitisqnksnhrdldismkytvngga
visqdyimr

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6cu3F (F:)
mahhhhhhmndfhhdfqqqqpttgiheemlkdgirtnayknailqnkhlfkdkvvldigc
gtgilclfaakagakrvigidmsdiidkarqivsdngyshvielikgkvediaqlpfgie
kvdiiisewmgyfllyesmlqtvlsardrwlrpggylfpdkctmyicgiedseykrdkid
fwdnvygfnfsaikadalreplvdfvesqqiittqskfleidlntiqpedlkqittsfef
tsqyqeycqafvawfdcvfsrgphkpvefstgpftegthwkqtvfylendlplkpndvik
gtitisqnksnhrdldismkytvnggavisqdyimr

    Sequence, based on observed residues (ATOM records): (download) 
    >6cu3F (F:)
emlkdgirtnayknailqnlfkdkvvldigcgtgilclfaakagasdiidkarqivsdng
yshvielikgkveisewmgyfllyesmlqtvlsardrwldkctmyicgiedseykrdkid
fwdnvygfnfsaikadalreplvdfvesqqiittqskfleidlntiqpedlkqittsfef
tsqyqeycqafvawfdcvfsvefstgpftegthwkqtvfylendlplkpndvikgtitis
qnksnhrdldismkytvnggavisqdyimr