PDB entry 6bt0

View 6bt0 on RCSB PDB site
Description: crystal structure of rheb in complex with compound nr1
Class: signaling protein
Keywords: mTORC1 G-protein, SIGNALING PROTEIN
Deposited on 2017-12-04, released 2018-02-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-10-21, with a file datestamp of 2020-10-16.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: GTP-binding protein Rheb
    Species: Homo sapiens [TaxId:9606]
    Gene: RHEB, RHEB2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q15382 (Start-169)
      • expression tag (170-171)
    Domains in SCOPe 2.08: d6bt0a1, d6bt0a2
  • Chain 'B':
    Compound: GTP-binding protein Rheb
    Species: Homo sapiens [TaxId:9606]
    Gene: RHEB, RHEB2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q15382 (Start-169)
      • expression tag (170)
    Domains in SCOPe 2.08: d6bt0b1, d6bt0b2
  • Chain 'C':
    Compound: GTP-binding protein Rheb
    Species: Homo sapiens [TaxId:9606]
    Gene: RHEB, RHEB2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q15382 (Start-169)
      • expression tag (170)
    Domains in SCOPe 2.08: d6bt0c1, d6bt0c2
  • Chain 'D':
    Compound: GTP-binding protein Rheb
    Species: Homo sapiens [TaxId:9606]
    Gene: RHEB, RHEB2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q15382 (Start-169)
      • expression tag (170)
    Domains in SCOPe 2.08: d6bt0d1, d6bt0d2
  • Heterogens: E7V, MG, GDP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6bt0A (A:)
smpqsksrkiailgyrsvgkssltiqfvegqfvdsydptientftklitvngqeyhlqlv
dtagqdeysifpqtysidingyilvysvtsiksfevikvihgklldmvgkvqipimlvgn
kkdlhmervisyeegkalaeswnaaflessakenqtavdvfrriileaeklehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6bt0A (A:)
qsksrkiailgyrsvgkssltiqfvegqfvdsydptientftklitvngqeyhlqlvdta
gqdeysifpqtysidingyilvysvtsiksfevikvihgklldmvgkvqipimlvgnkkd
lhmervisyeegkalaeswnaaflessakenqtavdvfrriileaekle

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6bt0B (B:)
smpqsksrkiailgyrsvgkssltiqfvegqfvdsydptientftklitvngqeyhlqlv
dtagqdeysifpqtysidingyilvysvtsiksfevikvihgklldmvgkvqipimlvgn
kkdlhmervisyeegkalaeswnaaflessakenqtavdvfrriileaeklehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6bt0B (B:)
qsksrkiailgyrsvgkssltiqfvegqfvdsydptientftklitvngqeyhlqlvdta
gqdeysifpqtysidingyilvysvtsiksfevikvihgklldmvgkvqipimlvgnkkd
lhmervisyeegkalaeswnaaflessakenqtavdvfrriileaekl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6bt0C (C:)
smpqsksrkiailgyrsvgkssltiqfvegqfvdsydptientftklitvngqeyhlqlv
dtagqdeysifpqtysidingyilvysvtsiksfevikvihgklldmvgkvqipimlvgn
kkdlhmervisyeegkalaeswnaaflessakenqtavdvfrriileaeklehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6bt0C (C:)
qsksrkiailgyrsvgkssltiqfvegqfvdsydptientftklitvngqeyhlqlvdta
gqdeysifpqtysidingyilvysvtsiksfevikvihgklldmvgkvqipimlvgnkkd
lhmervisyeegkalaeswnaaflessakenqtavdvfrriileaekl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6bt0D (D:)
smpqsksrkiailgyrsvgkssltiqfvegqfvdsydptientftklitvngqeyhlqlv
dtagqdeysifpqtysidingyilvysvtsiksfevikvihgklldmvgkvqipimlvgn
kkdlhmervisyeegkalaeswnaaflessakenqtavdvfrriileaeklehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6bt0D (D:)
qsksrkiailgyrsvgkssltiqfvegqfvdsydptientftklitvngqeyhlqlvdta
gqdeysifpqtysidingyilvysvtsiksfevikvihgklldmvgkvqipimlvgnkkd
lhmervisyeegkalaeswnaaflessakenqtavdvfrriileaekl