PDB entry 5n3w

View 5n3w on RCSB PDB site
Description: Crystal structure of LTA4H bound to a selective inhibitor against LTB4 generation
Class: hydrolase
Keywords: Hydrolase, Inflammation
Deposited on 2017-02-09, released 2017-03-29
The last revision prior to the SCOPe 2.06 freeze date was dated 2017-03-29, with a file datestamp of 2017-03-24.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Leukotriene A-4 hydrolase
    Species: Homo sapiens [TaxId:9606]
    Gene: LTA4H, LTA4
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d5n3wa1, d5n3wa2, d5n3wa3
  • Heterogens: ZN, YB, IMD, 8KW, ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5n3wA (A:)
mpeivdtcslaspasvcrtkhlhlrcsvdftrrtltgtaaltvqsqednlrslvldtkdl
tiekvvingqevkyalgerqsykgspmeislpialsknqeivieisfetspkssalqwlt
peqtsgkehpylfsqcqaihcrailpcqdtpsvkltytaevsvpkelvalmsairdgetp
dpedpsrkiykfiqkvpipcylialvvgalesrqigprtlvwsekeqveksayefsetes
mlkiaedlggpyvwgqydllvlppsfpyggmenpcltfvtptllagdkslsnviaheish
swtgnlvtnktwdhfwlneghtvylerhicgrlfgekfrhfnalggwgelqnsvktfget
hpftklvvdltdidpdvayssvpyekgfallfyleqllggpeiflgflkayvekfsyksi
ttddwkdflysyfkdkvdvlnqvdwnawlyspglppikpnydmtltnacialsqrwitak
eddlnsfnatdlkdlsshqlneflaqtlqraplplghikrmqevynfnainnseirfrwl
rlciqskwedaiplalkmateqgrmkftrplfkdlaafdkshdqavrtyqehkasmhpvt
amlvgkdlkvdvdhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >5n3wA (A:)
vdtcslaspasvcrtkhlhlrcsvdftrrtltgtaaltvqsqednlrslvldtkdltiek
vvingqevkyalgerqsykgspmeislpialsknqeivieisfetspkssalqwltpeqt
sgkehpylfsqcqaihcrailpcqdtpsvkltytaevsvpkelvalmsairdgetpdped
psrkiykfiqkvpipcylialvvgalesrqigprtlvwsekeqveksayefsetesmlki
aedlggpyvwgqydllvlppsfpyggmenpcltfvtptllagdkslsnviaheishswtg
nlvtnktwdhfwlneghtvylerhicgrlfgekfrhfnalggwgelqnsvktfgethpft
klvvdltdidpdvayssvpyekgfallfyleqllggpeiflgflkayvekfsyksittdd
wkdflysyfkdkvdvlnqvdwnawlyspglppikpnydmtltnacialsqrwitakeddl
nsfnatdlkdlsshqlneflaqtlqraplplghikrmqevynfnainnseirfrwlrlci
qskwedaiplalkmateqgrmkftrplfkdlaafdkshdqavrtyqehkasmhpvtamlv
gkdlkv