SCOPe 2.06: Domain d5n3wa2: 5n3w A:209-460

Lineage for d5n3wa2 (5n3w A:209-460)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.92: Zincin-like [55485] (2 superfamilies)
   contains mixed beta sheet with connection over free side of the sheet

4. Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (18 families)

5. Family d.92.1.13: Zn aminopeptidase catalytic domain [64338] (5 proteins)
   adopts thermolysin-like fold

6. Protein Leukotriene A4 hydrolase catalytic domain [64339] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [64340] (56 PDB entries)
   Uniprot P09960

8. Domain d5n3wa2: 5n3w A:209-460 [332474]
   Other proteins in same PDB: d5n3wa1, d5n3wa3
   automated match to d3u9wa2
   complexed with 8kw, act, imd, yb, zn

Details for d5n3wa2

PDB Entry: 5n3w, 2.3 Å

PDB Description: crystal structure of lta4h bound to a selective inhibitor against ltb4 generation

PDB Compounds: (A:) Leukotriene A-4 hydrolase

SCOPe Domain Sequences for d5n3wa2:

Sequence; same for both SEQRES and ATOM records:

>d5n3wa2 d.92.1.13 (A:209-460) Leukotriene A4 hydrolase catalytic domain {Human (Homo sapiens) [TaxId: 9606]}
lesrqigprtlvwsekeqveksayefsetesmlkiaedlggpyvwgqydllvlppsfpyg
gmenpcltfvtptllagdkslsnviaheishswtgnlvtnktwdhfwlneghtvylerhi
cgrlfgekfrhfnalggwgelqnsvktfgethpftklvvdltdidpdvayssvpyekgfa
llfyleqllggpeiflgflkayvekfsyksittddwkdflysyfkdkvdvlnqvdwnawl
yspglppikpny

Timeline for d5n3wa2:

• d5n3wa2 is new in SCOPe 2.06-stable
  
• d5n3wa2 appears in SCOPe 2.07
  
• d5n3wa2 appears in the current release, SCOPe 2.08