PDB entry 5jl4

View 5jl4 on RCSB PDB site
Description: Inhibitor resistant mutant catalytic core domain of HIV-1 Integrase
Class: DNA binding protein
Keywords: Allini HIV Integrase Multimerization, DNA BINDING PROTEIN
Deposited on 2016-04-26, released 2017-10-04
The last revision prior to the SCOPe 2.06 freeze date was dated 2017-10-04, with a file datestamp of 2017-09-29.
Experiment type: XRAY
Resolution: 1.76 Å
R-factor: N/A
AEROSPACI score: 0.39 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: integrase
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot D0ENR2
      • engineered mutation (115)
      • engineered mutation (124)
      • engineered mutation (135)
    Domains in SCOPe 2.06: d5jl4a_
  • Chain 'B':
    Compound: integrase
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: pol
    Database cross-references and differences (RAF-indexed):
    • Uniprot D0ENR2
      • engineered mutation (115)
      • engineered mutation (124)
      • engineered mutation (135)
    Domains in SCOPe 2.06: d5jl4b_
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >5jl4A (A:)
mhgqvdcspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwp
vktvhtdngsnftsntvkaacwwagikqefgipynpqsqgviesmnkelkkiigqirdqa
ehlkiavqmavfihnkkrkggiggysagerivdiiatdiqtke

    Sequence, based on observed residues (ATOM records): (download) 
    >5jl4A (A:)
cspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvht
dngsnftsntvkaacwwagikqefgipynviesmnkelkkiigqirdqaehlkiavqmav
fihnkkrkggiggysagerivdiiatdiq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >5jl4B (B:)
mhgqvdcspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwp
vktvhtdngsnftsntvkaacwwagikqefgipynpqsqgviesmnkelkkiigqirdqa
ehlkiavqmavfihnkkrkggiggysagerivdiiatdiqtke

    Sequence, based on observed residues (ATOM records): (download) 
    >5jl4B (B:)
cspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvht
dngsnftsntvkaacwwagikqefgviesmnkelkkiigqirdqaehlkiavqmavfihn
kkrkggiggysagerivdiiatdiq