PDB entry 5j1r

View 5j1r on RCSB PDB site
Description: Structure of Transcriptional Regulatory Repressor Protein - EthR from Mycobacterium Tuberculosis in complex with 3-(furan-3-yl)-1-(pyrrolidin-1-yl)propan-1-one at 1.92A resolution
Class: transcription
Keywords: EthR, transcription, represor, boosting effect
Deposited on 2016-03-29, released 2017-03-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2017-09-13, with a file datestamp of 2017-09-08.
Experiment type: XRAY
Resolution: 1.92 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: EthR
  Species: Mycobacterium tuberculosis [TaxId:1773]
  Gene: ethR_2, ethR, ethR_1, AFL40_4013, BN1213_00375, BN1303_02839, ERS007657_00006, ERS007665_03402, ERS007670_00101, ERS007672_00126, ERS007679_01009, ERS007681_01169, ERS007688_00760, ERS007703_00420, ERS007722_01164, ERS007741_02569, ERS013447_02283, ERS013471_02551, ERS023446_02032, ERS024213_01441, ERS024276_01130, ERS027644_00684, ERS027646_02322, ERS027654_00374, ERS027656_00876, ERS031537_01716, ERS075357_02728, ERS075361_00362, ERS075387_01097, ERS124361_02860, IQ38_20160, IQ40_19545, IQ45_19480, IQ47_19420, IU13_19735, IU16_19625
  Database cross-references and differences (RAF-indexed):
  • Uniprot A0A045KCS8
  Domains in SCOPe 2.08: d5j1ra1, d5j1ra2
• Heterogens: 6FG, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence, based on SEQRES records: (download)
  

  >5j1rA (A:)
  mttsaasqaslprgrrtarpsgddrelailataenlledrpladisvddlakgagisrpt
  fyfyfpskeavlltlldrvvnqadmalqtlaenpadtdrenmwrtginvffetfgshkav
  tragqaaratsvevaelwstfmqkwiaytaavidaerdrgaaprtlpahelatalnlmne
  rtlfasfageqpsvpearvldtlvhiwvtsiygenr
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >5j1rA (A:)
  gddrelailataenlledrpladisvddlakgagisrptfyfyfpskeavlltlldrvvn
  qadmalqtlaenpadtdrenmwrtginvffetfgshkavtragqaaratsvevaelwstf
  mqkwiaytaavidaerdrgaaprtlpahelatalnlmnertlfasfageqpsvpearvld
  tlvhiwvtsiyge