PDB entry 3omu

View 3omu on RCSB PDB site
Description: Crystal Structure of the N-terminal domain of an HSP90 from Trypanosoma Brucei, Tb10.26.1080 in the presence of a thienopyrimidine derivative
Class: chaperone
Keywords: hsp90, Trypanosoma bruceii, structural genomics, drug discovery, Structural Genomics Consortium, SGC, chaperone
Deposited on 2010-08-27, released 2010-10-27
The last revision prior to the SCOPe 2.02 freeze date was dated 2010-10-27, with a file datestamp of 2010-10-22.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: 0.226
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Heat shock protein 83
    Species: Trypanosoma brucei [TaxId:5691]
    Gene: Tb10.26.1080
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q389P1 (18-End)
      • expression tag (17)
  • Chain 'B':
    Compound: Heat shock protein 83
    Species: Trypanosoma brucei [TaxId:5691]
    Gene: Tb10.26.1080
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d3omub_
  • Heterogens: IBD, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >3omuB (B:)
mhhhhhhssgrenlyfqgmtetfafqaeinqlmsliintfysnkeiflrelisnssdacd
kiryqsltnqsvlgdephlrirvipdrvnktltvedsgigmtkadlvnnlgtiarsgtks
fmealeaggdmsmigqfgvgfysaylvadrvtvvsknneddaytwessaggtftvtstpd
cdlkrgtrivlhlkedqqeyleerrlkdlikkhsefigydielmventtek

    Sequence, based on observed residues (ATOM records): (download) 
    >3omuB (B:)
mtetfafqaeinqlmsliintfysnkeiflrelisnssdacdkiryqsltnqsvlgdhlr
irvipdrvnktltvedsgigmtkadlvnnlgtiarsgtksfmealeaggdmsmigqfgvg
fysaylvadrvtvvsknneddaytwesgtftvtstpdcdlkrgtrivlhlkedqqeylee
rrlkdlikkhsigydielm