PDB entry 2vkx

View 2vkx on RCSB PDB site
Description: human ncam, fn3 domains 1 and 2, m610r mutant
Class: cell adhesion
Keywords: adhesion receptor, cell adhesion
Deposited on 2008-01-04, released 2008-02-26
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.2233
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: neural cell adhesion molecule
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2VKX (200-End)
      • engineered mutation (118)
    • Uniprot P13591 (108-199)
    Domains in SCOPe 2.07: d2vkxa1, d2vkxa2, d2vkxa3
  • Chain 'B':
    Compound: neural cell adhesion molecule
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2VKX (200-End)
      • engineered mutation (118)
    • Uniprot P13591 (108-199)
    Domains in SCOPe 2.07: d2vkxb1, d2vkxb2, d2vkxb3
  • Chain 'C':
    Compound: neural cell adhesion molecule
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2VKX (200-End)
      • engineered mutation (118)
    • Uniprot P13591 (108-199)
    Domains in SCOPe 2.07: d2vkxc1, d2vkxc2, d2vkxc3
  • Chain 'D':
    Compound: neural cell adhesion molecule
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2VKX (200-End)
      • engineered mutation (118)
    • Uniprot P13591 (108-199)
    Domains in SCOPe 2.07: d2vkxd1, d2vkxd2, d2vkxd3
  • Chain 'E':
    Compound: neural cell adhesion molecule
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2VKX (200-End)
      • engineered mutation (118)
    • Uniprot P13591 (108-199)
    Domains in SCOPe 2.07: d2vkxe1, d2vkxe2, d2vkxe3
  • Chain 'F':
    Compound: neural cell adhesion molecule
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2VKX (200-End)
      • engineered mutation (118)
    • Uniprot P13591 (108-199)
    Domains in SCOPe 2.07: d2vkxf1, d2vkxf2, d2vkxf3
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vkxA (A:)
aplaqadtpsspsidqvepysstaqvqfdepeatggvpilkykaewravgeevwhskwyd
akeasmegivtivglkpettyavrlaalngkglgeisaasefktqpvrepsapklegqrg
edgnsikvnlikqddggspirhylvryralssewkpeirlpsgsdhvmlksldwnaeyev
yvvaenqqgkskaahfvfrtaaahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2vkxA (A:)
adtpsspsidqvepysstaqvqfdepeatggvpilkykaewravgeevwhskwydakeas
megivtivglkpettyavrlaalngkglgeisaasefktqpvrepsapklegqrgedgns
ikvnlikqddggspirhylvryralssewkpeirlpsgsdhvmlksldwnaeyevyvvae
nqqgkskaahfvfrtaaah

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2vkxB (B:)
aplaqadtpsspsidqvepysstaqvqfdepeatggvpilkykaewravgeevwhskwyd
akeasmegivtivglkpettyavrlaalngkglgeisaasefktqpvrepsapklegqrg
edgnsikvnlikqddggspirhylvryralssewkpeirlpsgsdhvmlksldwnaeyev
yvvaenqqgkskaahfvfrtaaahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2vkxB (B:)
adtpsspsidqvepysstaqvqfdepeatggvpilkykaewravgeevwhskwydakeas
megivtivglkpettyavrlaalngkglgeisaasefktqpvrepsapklegqrgedgns
ikvnlikqddggspirhylvryralssewkpeirlpsgsdhvmlksldwnaeyevyvvae
nqqgkskaahfvfrtaaa

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2vkxC (C:)
aplaqadtpsspsidqvepysstaqvqfdepeatggvpilkykaewravgeevwhskwyd
akeasmegivtivglkpettyavrlaalngkglgeisaasefktqpvrepsapklegqrg
edgnsikvnlikqddggspirhylvryralssewkpeirlpsgsdhvmlksldwnaeyev
yvvaenqqgkskaahfvfrtaaahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2vkxC (C:)
adtpsspsidqvepysstaqvqfdepeatggvpilkykaewravgeevwhskwydakeas
megivtivglkpettyavrlaalngkglgeisaasefktqpvrepsapklegqrgedgns
ikvnlikqddggspirhylvryralssewkpeirlpsgsdhvmlksldwnaeyevyvvae
nqqgkskaahfvfrtaaah

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2vkxD (D:)
aplaqadtpsspsidqvepysstaqvqfdepeatggvpilkykaewravgeevwhskwyd
akeasmegivtivglkpettyavrlaalngkglgeisaasefktqpvrepsapklegqrg
edgnsikvnlikqddggspirhylvryralssewkpeirlpsgsdhvmlksldwnaeyev
yvvaenqqgkskaahfvfrtaaahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2vkxD (D:)
adtpsspsidqvepysstaqvqfdepeatggvpilkykaewravgeevwhskwydakeas
megivtivglkpettyavrlaalngkglgeisaasefktqpvrepsapklegqrgedgns
ikvnlikqddggspirhylvryralssewkpeirlpsgsdhvmlksldwnaeyevyvvae
nqqgkskaahfvfrtaaah

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2vkxE (E:)
aplaqadtpsspsidqvepysstaqvqfdepeatggvpilkykaewravgeevwhskwyd
akeasmegivtivglkpettyavrlaalngkglgeisaasefktqpvrepsapklegqrg
edgnsikvnlikqddggspirhylvryralssewkpeirlpsgsdhvmlksldwnaeyev
yvvaenqqgkskaahfvfrtaaahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2vkxE (E:)
aplaqadtpsspsidqvepysstaqvqfdepeatggvpilkykaewravgeevwhskwyd
akeasmegivtivglkpettyavrlaalngkglgeisaasefktqpvrepsapklegqrg
edgnsikvnlikqddggspirhylvryralssewkpeirlpsgsdhvmlksldwnaeyev
yvvaenqqgkskaahfvfrtaaa

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2vkxF (F:)
aplaqadtpsspsidqvepysstaqvqfdepeatggvpilkykaewravgeevwhskwyd
akeasmegivtivglkpettyavrlaalngkglgeisaasefktqpvrepsapklegqrg
edgnsikvnlikqddggspirhylvryralssewkpeirlpsgsdhvmlksldwnaeyev
yvvaenqqgkskaahfvfrtaaahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >2vkxF (F:)
adtpsspsidqvepysstaqvqfdepeatggvpilkykaewravgeevwhskwydakeas
megivtivglkpettyavrlaalngkglgeisaasefktqpvrepsapklegqrgedgns
ikvnlikqddggspirhylvryralssewkpeirlpsgsdhvmlksldwnaeyevyvvae
nqqgkskaahfvfrtaaah