PDB entry 2bgn

View 2bgn on RCSB PDB site
Description: hiv-1 tat protein derived n-terminal nonapeptide trp2-tat (1-9) bound to the active site of dipeptidyl peptidase IV (cd26)
Class: hydrolase
Keywords: hydrolase, hydrolase/complex, dipetidyl peptidase IV, dppiv, cd26, alpha/beta-hydrolase fold, beta-propeller fold, protein-protein complex, adenosine deaminase, ada, serine protease, aminopeptidase, hiv-1 tat protein
Deposited on 2005-01-03, released 2005-01-27
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 3.15 Å
R-factor: 0.227
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dipeptidyl peptidase IV
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2bgna1, d2bgna2
  • Chain 'B':
    Compound: dipeptidyl peptidase IV
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2bgnb1, d2bgnb2
  • Chain 'C':
    Compound: dipeptidyl peptidase IV
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2bgnc1, d2bgnc2
  • Chain 'D':
    Compound: dipeptidyl peptidase IV
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2bgnd1, d2bgnd2
  • Chain 'E':
    Compound: adenosine deaminase
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • PDB 2BGN
      • conflict see remark 9 (7)
      • conflict see remark 9 (31-32)
      • conflict (46)
      • conflict see remark 9 (56)
      • conflict see remark 9 (59)
      • conflict see remark 9 (76)
      • conflict see remark 9 (78)
      • variant (198)
      • variant (245)
      • conflict see remark 9 (260)
      • conflict see remark 9 (278)
      • conflict see remark 9 (280)
      • conflict see remark 9 (312-313)
      • variant (351)
    • Uniprot P56658
    Domains in SCOPe 2.03: d2bgne1
  • Chain 'F':
    Compound: adenosine deaminase
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • PDB 2BGN
      • conflict see remark 9 (7)
      • conflict see remark 9 (31-32)
      • conflict (46)
      • conflict see remark 9 (56)
      • conflict see remark 9 (59)
      • conflict see remark 9 (76)
      • conflict see remark 9 (78)
      • variant (198)
      • variant (245)
      • conflict see remark 9 (260)
      • conflict see remark 9 (278)
      • conflict see remark 9 (280)
      • conflict see remark 9 (312-313)
      • variant (351)
    • Uniprot P56658
    Domains in SCOPe 2.03: d2bgnf1
  • Chain 'G':
    Compound: adenosine deaminase
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • PDB 2BGN
      • conflict see remark 9 (7)
      • conflict see remark 9 (31-32)
      • conflict (46)
      • conflict see remark 9 (56)
      • conflict see remark 9 (59)
      • conflict see remark 9 (76)
      • conflict see remark 9 (78)
      • variant (198)
      • variant (245)
      • conflict see remark 9 (260)
      • conflict see remark 9 (278)
      • conflict see remark 9 (280)
      • conflict see remark 9 (312-313)
      • variant (351)
    • Uniprot P56658
    Domains in SCOPe 2.03: d2bgng1
  • Chain 'H':
    Compound: adenosine deaminase
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • PDB 2BGN
      • conflict see remark 9 (7)
      • conflict see remark 9 (31-32)
      • conflict (46)
      • conflict see remark 9 (56)
      • conflict see remark 9 (59)
      • conflict see remark 9 (76)
      • conflict see remark 9 (78)
      • variant (198)
      • variant (245)
      • conflict see remark 9 (260)
      • conflict see remark 9 (278)
      • conflict see remark 9 (280)
      • conflict see remark 9 (312-313)
      • variant (351)
    • Uniprot P56658
    Domains in SCOPe 2.03: d2bgnh1
  • Chain 'W':
    Compound: tat protein
    Species: HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, synthetic [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12506 (0-End)
      • engineered mutation (1)
  • Chain 'X':
    Compound: tat protein
    Species: HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, synthetic [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12506 (0-End)
      • engineered mutation (1)
  • Chain 'Y':
    Compound: tat protein
    Species: HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, synthetic [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12506 (0-End)
      • engineered mutation (1)
  • Chain 'Z':
    Compound: tat protein
    Species: HUMAN IMMUNODEFICIENCY VIRUS TYPE 1, synthetic [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12506 (0-End)
      • engineered mutation (1)
  • Heterogens: NAG, ZN

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2bgnA (A:)
srktytltdylkntyrlklyslrwisdheylykqennilvfnaeygnssvflenstfdef
ghsindysispdgqfilleynyvkqwrhsytasydiydlnkrqliteeripnntqwvtws
pvghklayvwnndiyvkiepnlpsyritwtgkediiyngitdwvyeeevfsaysalwwsp
ngtflayaqfndtevplieysfysdeslqypktvrvpypkagavnptvkffvvntdslss
vtnatsiqitapasmligdhylcdvtwatqerislqwlrriqnysvmdicdydessgrwn
clvarqhiemsttgwvgrfrpsephftldgnsfykiisneegyrhicyfqidkkdctfit
kgtwevigiealtsdylyyisneykgmpggrnlykiqlsdytkvtclscelnpercqyys
vsfskeakyyqlrcsgpglplytlhssvndkglrvlednsaldkmlqnvqmpskkldfii
lnetkfwyqmilpphfdkskkypllldvyagpcsqkadtvfrlnwatylasteniivasf
dgrgsgyqgdkimhainrrlgtfevedqieaarqfskmgfvdnkriaiwgwsyggyvtsm
vlgsgsgvfkcgiavapvsrweyydsvyterymglptpednldhyrnstvmsraenfkqv
eyllihgtaddnvhfqqsaqiskalvdvgvdfqamwytdedhgiasstahqhiythmshf
ikqcfslp

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2bgnB (B:)
srktytltdylkntyrlklyslrwisdheylykqennilvfnaeygnssvflenstfdef
ghsindysispdgqfilleynyvkqwrhsytasydiydlnkrqliteeripnntqwvtws
pvghklayvwnndiyvkiepnlpsyritwtgkediiyngitdwvyeeevfsaysalwwsp
ngtflayaqfndtevplieysfysdeslqypktvrvpypkagavnptvkffvvntdslss
vtnatsiqitapasmligdhylcdvtwatqerislqwlrriqnysvmdicdydessgrwn
clvarqhiemsttgwvgrfrpsephftldgnsfykiisneegyrhicyfqidkkdctfit
kgtwevigiealtsdylyyisneykgmpggrnlykiqlsdytkvtclscelnpercqyys
vsfskeakyyqlrcsgpglplytlhssvndkglrvlednsaldkmlqnvqmpskkldfii
lnetkfwyqmilpphfdkskkypllldvyagpcsqkadtvfrlnwatylasteniivasf
dgrgsgyqgdkimhainrrlgtfevedqieaarqfskmgfvdnkriaiwgwsyggyvtsm
vlgsgsgvfkcgiavapvsrweyydsvyterymglptpednldhyrnstvmsraenfkqv
eyllihgtaddnvhfqqsaqiskalvdvgvdfqamwytdedhgiasstahqhiythmshf
ikqcfslp

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2bgnC (C:)
srktytltdylkntyrlklyslrwisdheylykqennilvfnaeygnssvflenstfdef
ghsindysispdgqfilleynyvkqwrhsytasydiydlnkrqliteeripnntqwvtws
pvghklayvwnndiyvkiepnlpsyritwtgkediiyngitdwvyeeevfsaysalwwsp
ngtflayaqfndtevplieysfysdeslqypktvrvpypkagavnptvkffvvntdslss
vtnatsiqitapasmligdhylcdvtwatqerislqwlrriqnysvmdicdydessgrwn
clvarqhiemsttgwvgrfrpsephftldgnsfykiisneegyrhicyfqidkkdctfit
kgtwevigiealtsdylyyisneykgmpggrnlykiqlsdytkvtclscelnpercqyys
vsfskeakyyqlrcsgpglplytlhssvndkglrvlednsaldkmlqnvqmpskkldfii
lnetkfwyqmilpphfdkskkypllldvyagpcsqkadtvfrlnwatylasteniivasf
dgrgsgyqgdkimhainrrlgtfevedqieaarqfskmgfvdnkriaiwgwsyggyvtsm
vlgsgsgvfkcgiavapvsrweyydsvyterymglptpednldhyrnstvmsraenfkqv
eyllihgtaddnvhfqqsaqiskalvdvgvdfqamwytdedhgiasstahqhiythmshf
ikqcfslp

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2bgnD (D:)
srktytltdylkntyrlklyslrwisdheylykqennilvfnaeygnssvflenstfdef
ghsindysispdgqfilleynyvkqwrhsytasydiydlnkrqliteeripnntqwvtws
pvghklayvwnndiyvkiepnlpsyritwtgkediiyngitdwvyeeevfsaysalwwsp
ngtflayaqfndtevplieysfysdeslqypktvrvpypkagavnptvkffvvntdslss
vtnatsiqitapasmligdhylcdvtwatqerislqwlrriqnysvmdicdydessgrwn
clvarqhiemsttgwvgrfrpsephftldgnsfykiisneegyrhicyfqidkkdctfit
kgtwevigiealtsdylyyisneykgmpggrnlykiqlsdytkvtclscelnpercqyys
vsfskeakyyqlrcsgpglplytlhssvndkglrvlednsaldkmlqnvqmpskkldfii
lnetkfwyqmilpphfdkskkypllldvyagpcsqkadtvfrlnwatylasteniivasf
dgrgsgyqgdkimhainrrlgtfevedqieaarqfskmgfvdnkriaiwgwsyggyvtsm
vlgsgsgvfkcgiavapvsrweyydsvyterymglptpednldhyrnstvmsraenfkqv
eyllihgtaddnvhfqqsaqiskalvdvgvdfqamwytdedhgiasstahqhiythmshf
ikqcfslp

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2bgnE (E:)
maqtpafdkpkvelhvhldgaikpetilyygkrrgialpadtpeellniigmdkpltlpd
flakfdyympaiagcrdaikriayefvemkakdgvvyvevrysphllanskvepipwnqa
egdltpdevvslvnqglqegerdfgvkvrsilccmrhqpswssevvelckkyreqtvvai
dlagdetiegsslfpghvqayaeavksgvhrtvhagevgsanvvkeavdtlkterlghgy
htledttlynrlrqenmhfeicpwssyltgawkpdtehavirfkndqvnyslntddplif
kstldtdyqmtkkdmgfteeefkrlninaakssflpedekkelldllykayrmpspasae
qcl

    Sequence, based on observed residues (ATOM records): (download) 
    >2bgnE (E:)
tpafdkpkvelhvhldgaikpetilyygkrrgialpadtpeellniigmdkpltlpdfla
kfdyympaiagcrdaikriayefvemkakdgvvyvevrysphllanskvepipwnqaegd
ltpdevvslvnqglqegerdfgvkvrsilccmrhqpswssevvelckkyreqtvvaidla
gdetiegsslfpghvqayaeavksgvhrtvhagevgsanvvkeavdtlkterlghgyhtl
edttlynrlrqenmhfeicpwssyltgawkpdtehavirfkndqvnyslntddplifkst
ldtdyqmtkkdmgfteeefkrlninaakssflpedekkelldllykayrmps

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2bgnF (F:)
maqtpafdkpkvelhvhldgaikpetilyygkrrgialpadtpeellniigmdkpltlpd
flakfdyympaiagcrdaikriayefvemkakdgvvyvevrysphllanskvepipwnqa
egdltpdevvslvnqglqegerdfgvkvrsilccmrhqpswssevvelckkyreqtvvai
dlagdetiegsslfpghvqayaeavksgvhrtvhagevgsanvvkeavdtlkterlghgy
htledttlynrlrqenmhfeicpwssyltgawkpdtehavirfkndqvnyslntddplif
kstldtdyqmtkkdmgfteeefkrlninaakssflpedekkelldllykayrmpspasae
qcl

    Sequence, based on observed residues (ATOM records): (download) 
    >2bgnF (F:)
tpafdkpkvelhvhldgaikpetilyygkrrgialpadtpeellniigmdkpltlpdfla
kfdyympaiagcrdaikriayefvemkakdgvvyvevrysphllanskvepipwnqaegd
ltpdevvslvnqglqegerdfgvkvrsilccmrhqpswssevvelckkyreqtvvaidla
gdetiegsslfpghvqayaeavksgvhrtvhagevgsanvvkeavdtlkterlghgyhtl
edttlynrlrqenmhfeicpwssyltgawkpdtehavirfkndqvnyslntddplifkst
ldtdyqmtkkdmgfteeefkrlninaakssflpedekkelldllykayrmps

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >2bgnG (G:)
maqtpafdkpkvelhvhldgaikpetilyygkrrgialpadtpeellniigmdkpltlpd
flakfdyympaiagcrdaikriayefvemkakdgvvyvevrysphllanskvepipwnqa
egdltpdevvslvnqglqegerdfgvkvrsilccmrhqpswssevvelckkyreqtvvai
dlagdetiegsslfpghvqayaeavksgvhrtvhagevgsanvvkeavdtlkterlghgy
htledttlynrlrqenmhfeicpwssyltgawkpdtehavirfkndqvnyslntddplif
kstldtdyqmtkkdmgfteeefkrlninaakssflpedekkelldllykayrmpspasae
qcl

    Sequence, based on observed residues (ATOM records): (download) 
    >2bgnG (G:)
tpafdkpkvelhvhldgaikpetilyygkrrgialpadtpeellniigmdkpltlpdfla
kfdyympaiagcrdaikriayefvemkakdgvvyvevrysphllanskvepipwnqaegd
ltpdevvslvnqglqegerdfgvkvrsilccmrhqpswssevvelckkyreqtvvaidla
gdetiegsslfpghvqayaeavksgvhrtvhagevgsanvvkeavdtlkterlghgyhtl
edttlynrlrqenmhfeicpwssyltgawkpdtehavirfkndqvnyslntddplifkst
ldtdyqmtkkdmgfteeefkrlninaakssflpedekkelldllykayrmps

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2bgnH (H:)
maqtpafdkpkvelhvhldgaikpetilyygkrrgialpadtpeellniigmdkpltlpd
flakfdyympaiagcrdaikriayefvemkakdgvvyvevrysphllanskvepipwnqa
egdltpdevvslvnqglqegerdfgvkvrsilccmrhqpswssevvelckkyreqtvvai
dlagdetiegsslfpghvqayaeavksgvhrtvhagevgsanvvkeavdtlkterlghgy
htledttlynrlrqenmhfeicpwssyltgawkpdtehavirfkndqvnyslntddplif
kstldtdyqmtkkdmgfteeefkrlninaakssflpedekkelldllykayrmpspasae
qcl

    Sequence, based on observed residues (ATOM records): (download) 
    >2bgnH (H:)
tpafdkpkvelhvhldgaikpetilyygkrrgialpadtpeellniigmdkpltlpdfla
kfdyympaiagcrdaikriayefvemkakdgvvyvevrysphllanskvepipwnqaegd
ltpdevvslvnqglqegerdfgvkvrsilccmrhqpswssevvelckkyreqtvvaidla
gdetiegsslfpghvqayaeavksgvhrtvhagevgsanvvkeavdtlkterlghgyhtl
edttlynrlrqenmhfeicpwssyltgawkpdtehavirfkndqvnyslntddplifkst
ldtdyqmtkkdmgfteeefkrlninaakssflpedekkelldllykayrmps

  • Chain 'W':
    No sequence available.

  • Chain 'X':
    No sequence available.

  • Chain 'Y':
    No sequence available.

  • Chain 'Z':
    No sequence available.