PDB entry 1s4e

View 1s4e on RCSB PDB site
Description: Pyrococcus furiosus galactokinase in complex with galactose, ADP and magnesium
Class: transferase
Keywords: GHMP kinase superfamily, P-loop, transferase
Deposited on 2004-01-16, released 2004-04-06
The last revision prior to the SCOPe 2.02 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.232
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Galactokinase
    Species: Pyrococcus furiosus [TaxId:2261]
    Gene: GALK
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HHB6
      • modified residue (26)
      • modified residue (28)
      • modified residue (292)
    Domains in SCOPe 2.02: d1s4ea1, d1s4ea2
  • Chain 'B':
    Compound: Galactokinase
    Species: Pyrococcus furiosus [TaxId:2261]
    Gene: GALK
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HHB6
      • modified residue (26)
      • modified residue (28)
      • modified residue (292)
    Domains in SCOPe 2.02: d1s4eb1, d1s4eb2
  • Chain 'C':
    Compound: Galactokinase
    Species: Pyrococcus furiosus [TaxId:2261]
    Gene: GALK
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HHB6
      • modified residue (26)
      • modified residue (28)
      • modified residue (292)
    Domains in SCOPe 2.02: d1s4ec1, d1s4ec2
  • Chain 'D':
    Compound: Galactokinase
    Species: Pyrococcus furiosus [TaxId:2261]
    Gene: GALK
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HHB6 (Start-351)
      • modified residue (26)
      • modified residue (28)
      • modified residue (292)
    Domains in SCOPe 2.02: d1s4ed1, d1s4ed2
  • Chain 'E':
    Compound: Galactokinase
    Species: Pyrococcus furiosus [TaxId:2261]
    Gene: GALK
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HHB6 (Start-351)
      • modified residue (26)
      • modified residue (28)
      • modified residue (292)
    Domains in SCOPe 2.02: d1s4ee1, d1s4ee2
  • Chain 'F':
    Compound: Galactokinase
    Species: Pyrococcus furiosus [TaxId:2261]
    Gene: GALK
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HHB6 (Start-351)
      • modified residue (26)
      • modified residue (28)
      • modified residue (292)
    Domains in SCOPe 2.02: d1s4ef1, d1s4ef2
  • Chain 'G':
    Compound: Galactokinase
    Species: Pyrococcus furiosus [TaxId:2261]
    Gene: GALK
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HHB6
      • modified residue (26)
      • modified residue (28)
      • modified residue (292)
    Domains in SCOPe 2.02: d1s4eg1, d1s4eg2
  • Chain 'H':
    Compound: Galactokinase
    Species: Pyrococcus furiosus [TaxId:2261]
    Gene: GALK
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HHB6
      • modified residue (26)
      • modified residue (28)
      • modified residue (292)
    Domains in SCOPe 2.02: d1s4eh1, d1s4eh2
  • Chain 'I':
    Compound: Galactokinase
    Species: Pyrococcus furiosus [TaxId:2261]
    Gene: GALK
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9HHB6 (Start-351)
      • modified residue (26)
      • modified residue (28)
      • modified residue (292)
    Domains in SCOPe 2.02: d1s4ei1, d1s4ei2
  • Heterogens: GLA, MG, ADP

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1s4eA (A:)
mskitvkspgrvnligehtdytygyvmpmaidlytiitaekydkvqlysehfneektftl
dnltkegswidyvkgvlwvliqegykigglkgkitgdlplgaglsssasfevgilevlnq
lynlnidplkkallakkaenefvgvpcgildqfavvfgkkdnvifldtqtlqyeyipfpk
dvsvlvfytgvkrelasseyaerkriaeeslrilgkesskevtekdlgklpplhrkffsy
ivrenarvlevrdalkegdiekvgkilttahwdlaenyrvsceeldffvkkamelgayga
rltgagfggsaialvdkdkaktigdailreylakfswkakyfvvkpsdgvgv

    Sequence, based on observed residues (ATOM records): (download) 
    >1s4eA (A:)
tvkspgrvnligehtdytygyvmpmaidlytiitdkvqlysehfnekldltkegswidyv
kgvlwvliqegykigglkkitgdlplgaglsssasfevgilevlnqlynlnidplkkall
akkaenefvgvpcgildqfavvfgkkdnvifldtqtlqyeyipfpkdvsvlvfytgvkre
lasseyaerkriaeeslrilgkesskevtekdlgklpplhrkffsyivrenarvlevrda
lkegdiekvgkilttahwdlaenyrvsceeldffvkkamelgaygarltgagfggsaial
vdkdkaktigdailreylakfswkakyfvvkpsdgvg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1s4eB (B:)
mskitvkspgrvnligehtdytygyvmpmaidlytiitaekydkvqlysehfneektftl
dnltkegswidyvkgvlwvliqegykigglkgkitgdlplgaglsssasfevgilevlnq
lynlnidplkkallakkaenefvgvpcgildqfavvfgkkdnvifldtqtlqyeyipfpk
dvsvlvfytgvkrelasseyaerkriaeeslrilgkesskevtekdlgklpplhrkffsy
ivrenarvlevrdalkegdiekvgkilttahwdlaenyrvsceeldffvkkamelgayga
rltgagfggsaialvdkdkaktigdailreylakfswkakyfvvkpsdgvgv

    Sequence, based on observed residues (ATOM records): (download) 
    >1s4eB (B:)
spgrvnligehtdytygyvmpmaidlytkydkvqlvkgvlwvliqegykigglkgitgdl
plgaglsssasfevgilevlnqlynlnidplkkallakkaenevgvpcgildqfavvfgk
kdnvifldtqtlqyeyipfpkdvsvlvfytgvkrelasseyaerkriaeeslrilgkess
kevtekdlgklpplhrkffsyivrenarvlevrdalkegdiekvgkilttahwdlaenyr
vsceeldffvkkamelgaygarltgagfggsaialvdkdkaktigdailreylakfswka
kyfvvkpsdg

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1s4eC (C:)
mskitvkspgrvnligehtdytygyvmpmaidlytiitaekydkvqlysehfneektftl
dnltkegswidyvkgvlwvliqegykigglkgkitgdlplgaglsssasfevgilevlnq
lynlnidplkkallakkaenefvgvpcgildqfavvfgkkdnvifldtqtlqyeyipfpk
dvsvlvfytgvkrelasseyaerkriaeeslrilgkesskevtekdlgklpplhrkffsy
ivrenarvlevrdalkegdiekvgkilttahwdlaenyrvsceeldffvkkamelgayga
rltgagfggsaialvdkdkaktigdailreylakfswkakyfvvkpsdgvgv

    Sequence, based on observed residues (ATOM records): (download) 
    >1s4eC (C:)
itvkspgrvnligehtdytygyvmpmaidlytiitaekkvqlysehfnektftldnlkeg
swidyvkgvlwvliqegyigglkgkitgdlplgaglsssasfevgilevlnqlynlnidp
lkkallakkaenefvgvpcgildqfavvfgkkdnvifldtqtlqyeyipfpkdvsvlvfy
tgvkrelasseyaerkriaeeslrilgkesskevtekdlgklpplhrkffsyivrenarv
levrdalkediekvgkilttahwdlaenyrvsceldffvkkamelaygarltgagfggsa
ialvdkdkaktigdalrelakfswkakyfvvkpsdgv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1s4eD (D:)
mskitvkspgrvnligehtdytygyvmpmaidlytiitaekydkvqlysehfneektftl
dnltkegswidyvkgvlwvliqegykigglkgkitgdlplgaglsssasfevgilevlnq
lynlnidplkkallakkaenefvgvpcgildqfavvfgkkdnvifldtqtlqyeyipfpk
dvsvlvfytgvkrelasseyaerkriaeeslrilgkesskevtekdlgklpplhrkffsy
ivrenarvlevrdalkegdiekvgkilttahwdlaenyrvsceeldffvkkamelgayga
rltgagfggsaialvdkdkaktigdailreylakfswkakyfvvkpsdgvgv

    Sequence, based on observed residues (ATOM records): (download) 
    >1s4eD (D:)
skitvkspgrvnligehtdytygyvmpmaidlytiitaekydkvqlysehfneektftld
tkegswidyvkgvlwvliqegykigglkgkitgdlplgaglsssasfevgilevlnqlyn
lnidplkkallakkaenefvgvpcgildqfavvfgkkdnvifldtqtlqyeyipfpkdvs
vlvfytgvkrelasseyaerkriaeeslrilgkesskevtekdlgklpplhrkffsyivr
enarvlevrdalkegdiekvgkilttahwdlaenyrvsceeldffvkkamelgaygarlt
gagfggsaialvdkdkaktigdailreylakfswkakyfvvkpsdgvgv

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1s4eE (E:)
mskitvkspgrvnligehtdytygyvmpmaidlytiitaekydkvqlysehfneektftl
dnltkegswidyvkgvlwvliqegykigglkgkitgdlplgaglsssasfevgilevlnq
lynlnidplkkallakkaenefvgvpcgildqfavvfgkkdnvifldtqtlqyeyipfpk
dvsvlvfytgvkrelasseyaerkriaeeslrilgkesskevtekdlgklpplhrkffsy
ivrenarvlevrdalkegdiekvgkilttahwdlaenyrvsceeldffvkkamelgayga
rltgagfggsaialvdkdkaktigdailreylakfswkakyfvvkpsdgvgv

    Sequence, based on observed residues (ATOM records): (download) 
    >1s4eE (E:)
kitvkspgrvnligehtdytygyvmpmaidlytiitaekydkvqlysehfneektftldn
ltkgswidyvkgvlwvliqegykigglkgkitgdlplgaglsssasfevgilevlnqlyn
lnidplkkallakkaenefvgvpcgildqfavvfgkkdnvifldtqtlqyeyipfpkdvs
vlvfytgvkelasseyaerkriaeeslrilgkesskevtekdlgklpplhrkffsyivre
narvlevrdalkegdiekvgkilttahwdlaenyrvsceeldffvkkamelgaygarltg
agfggsaialvdkdkaktigdailylakfswkakyfvvkpsdgvgv

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1s4eF (F:)
mskitvkspgrvnligehtdytygyvmpmaidlytiitaekydkvqlysehfneektftl
dnltkegswidyvkgvlwvliqegykigglkgkitgdlplgaglsssasfevgilevlnq
lynlnidplkkallakkaenefvgvpcgildqfavvfgkkdnvifldtqtlqyeyipfpk
dvsvlvfytgvkrelasseyaerkriaeeslrilgkesskevtekdlgklpplhrkffsy
ivrenarvlevrdalkegdiekvgkilttahwdlaenyrvsceeldffvkkamelgayga
rltgagfggsaialvdkdkaktigdailreylakfswkakyfvvkpsdgvgv

    Sequence, based on observed residues (ATOM records): (download) 
    >1s4eF (F:)
skitvkspgrvnligehtdytygyvmpmaidlytiitaekydkvqlysehfneektftld
nltkegswidyvkgvlwvliqegykigglkgkitgdlplgaglsssasfevgilevlnql
ynlnidplkkallakkaenefvgvpcgildqfavvfgkkdnvifldtqtlqyeyipfpkd
vsvlvfytgvkrelasseyaerkriaeeslrilgkesskevtekdlgklpplhrkffsyi
vrenarvlevrdalkegdiekvgkilttahwdlaenyrvsceeldffvkkamelgaygar
ltgagfggsaialvdkdkaktigdailreylakfswkakyfvvkpsdgvgv

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >1s4eG (G:)
mskitvkspgrvnligehtdytygyvmpmaidlytiitaekydkvqlysehfneektftl
dnltkegswidyvkgvlwvliqegykigglkgkitgdlplgaglsssasfevgilevlnq
lynlnidplkkallakkaenefvgvpcgildqfavvfgkkdnvifldtqtlqyeyipfpk
dvsvlvfytgvkrelasseyaerkriaeeslrilgkesskevtekdlgklpplhrkffsy
ivrenarvlevrdalkegdiekvgkilttahwdlaenyrvsceeldffvkkamelgayga
rltgagfggsaialvdkdkaktigdailreylakfswkakyfvvkpsdgvgv

    Sequence, based on observed residues (ATOM records): (download) 
    >1s4eG (G:)
rvnligehtdytygyvmpmaidlywidygvlwvliqegydlpsssasevgiledplkkal
lakkaenefvcgildqfavvfgnvifldtqtlqyeyipfpvlvfytgvkasseyaerkri
aeeslrilgkesskevtekdlgklpplhrkffsyivrenarvlevrdalegdiekvgkil
ttahwdlaenyrvsceeldffvkkamelgaygarltgagfggsaidkdaktigdailrey
lakfswkakfvvkps

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >1s4eH (H:)
mskitvkspgrvnligehtdytygyvmpmaidlytiitaekydkvqlysehfneektftl
dnltkegswidyvkgvlwvliqegykigglkgkitgdlplgaglsssasfevgilevlnq
lynlnidplkkallakkaenefvgvpcgildqfavvfgkkdnvifldtqtlqyeyipfpk
dvsvlvfytgvkrelasseyaerkriaeeslrilgkesskevtekdlgklpplhrkffsy
ivrenarvlevrdalkegdiekvgkilttahwdlaenyrvsceeldffvkkamelgayga
rltgagfggsaialvdkdkaktigdailreylakfswkakyfvvkpsdgvgv

    Sequence, based on observed residues (ATOM records): (download) 
    >1s4eH (H:)
skitvkspgrvnligehtdytygyvmpmaidlytiitaekykvqlysehfneektftldn
lkegswidyvkgvlwvliqegykigglkgkitgdlplgaglsssasfevgilevlnqlyn
lnidplkkallakkaenefvgvpcgildqfavvfgkkdnvifldtqtlqyeyipfpkdvs
vlvfytgvkrelasseyaerkriaeeslrilgkesskevtekdlgklpplhrkffsyivr
enarvlevrdalkegdiekvgkilttahwdlaenyrvsceeldffvkkamelgaygarlt
gagfggsaialvdkdkaktigdailreylakfswkakyfvvkpsdgv

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >1s4eI (I:)
mskitvkspgrvnligehtdytygyvmpmaidlytiitaekydkvqlysehfneektftl
dnltkegswidyvkgvlwvliqegykigglkgkitgdlplgaglsssasfevgilevlnq
lynlnidplkkallakkaenefvgvpcgildqfavvfgkkdnvifldtqtlqyeyipfpk
dvsvlvfytgvkrelasseyaerkriaeeslrilgkesskevtekdlgklpplhrkffsy
ivrenarvlevrdalkegdiekvgkilttahwdlaenyrvsceeldffvkkamelgayga
rltgagfggsaialvdkdkaktigdailreylakfswkakyfvvkpsdgvgv

    Sequence, based on observed residues (ATOM records): (download) 
    >1s4eI (I:)
skitvkspgrvnligehtdytygyvmpmaidlytiitaekydkvqlysehfneektftld
nltkegswidyvkgvlwvliqegykigglkgkitgdlplgaglsssasfevgilevlnql
ynlnidplkkallakkaenefvgvpcgildqfavvfgkkdnvifldtqtlqyeyipfpkd
vsvlvfytgvkrelasseyaerkriaeeslrilgkesskevtekdlgklpplhrkffsyi
vrenarvlevrdalkegdiekvgkilttahwdlaenyrvsceeldffvkkamelgaygar
ltgagfggsaialvdkdkaktigdailreylakfswkakyfvvkpsdgvgv