PDB entry 1oro

View 1oro on RCSB PDB site
Description: a flexible loop at the dimer interface is a part of the active site of the adjacent monomer of escherichia coli orotate phosphoribosyltransferase
Class: phosphoribosyltransferase
Keywords: pyrimidine nucleotide biosynthesis, inhibitor-enzyme complex, phosphoribosyltransferase
Deposited on 1995-09-11, released 1996-04-03
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.183
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: orotate phosphoribosyltransferase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1oroa_
  • Chain 'B':
    Compound: orotate phosphoribosyltransferase
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1orob_
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1oroA (A:)
mkpyqrqfiefalskqvlkfgeftlksgrkspyffnaglfntgrdlallgrfyaealvds
giefdllfgpaykgipiatttavalaehhdldlpycfnrkeakdhgeggnlvgsalqgrv
mlvddvitagtairesmeiiqangatlagvlisldrqergrgeisaiqeverdynckvis
iitlkdliayleekpemaehlaavkayreefgv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1oroB (B:)
mkpyqrqfiefalskqvlkfgeftlksgrkspyffnaglfntgrdlallgrfyaealvds
giefdllfgpaykgipiatttavalaehhdldlpycfnrkeakdhgeggnlvgsalqgrv
mlvddvitagtairesmeiiqangatlagvlisldrqergrgeisaiqeverdynckvis
iitlkdliayleekpemaehlaavkayreefgv

    Sequence, based on observed residues (ATOM records): (download) 
    >1oroB (B:)
mkpyqrqfiefalskqvlkfgeftlksgrkspyffnaglfntgrdlallgrfyaealvds
giefdllfgpaykgipiatttavalaehhdldlpycfnrkegnlvgsalqgrvmlvddvi
tagtairesmeiiqangatlagvlisldrqergrgeisaiqeverdynckvisiitlkdl
iayleekpemaehlaavkayreefgv