PDB entry 1nug

View 1nug on RCSB PDB site
Description: Role of Calcium Ions in the Activation and Activity of the Transglutaminase 3 Enzyme (2 calciums, 1 Mg, inactive form)
Class: transferase
Keywords: Transglutaminase 3, X-ray crystallography, metalloenzyme, calcium ion, TRANSFERASE
Deposited on 2003-01-31, released 2003-04-22
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.194
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Protein-glutamine glutamyltransferase E
    Species: Homo sapiens [TaxId:9606]
    Gene: TGM3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q08188 (0-691)
      • see remark 999 (249)
      • engineered (263)
      • see remark 999 (560)
      • see remark 999 (652)
    Domains in SCOPe 2.01: d1nuga1, d1nuga2, d1nuga3, d1nuga4
  • Chain 'B':
    Compound: Protein-glutamine glutamyltransferase E
    Species: Homo sapiens [TaxId:9606]
    Gene: TGM3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q08188 (0-691)
      • see remark 999 (249)
      • engineered (263)
      • see remark 999 (560)
      • see remark 999 (652)
    Domains in SCOPe 2.01: d1nugb1, d1nugb2, d1nugb3, d1nugb4
  • Heterogens: CL, CA, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1nugA (A:)
aalgvqsinwqtafnrqahhtdkfssqelilrrgqnfqvlmimnkglgsnerlefivstg
pypsesamtkavfplsngssggwsavlqasngntltisisspasapigrytmalqifsqg
gissvklgtfillfnpwlnvdsvfmgnhaereeyvqedagiifvgstnrigmigwnfgqf
eedilsiclsildrslnfrrdaatdvasrndpkyvgrvlsaminsnddngvlagnwsgty
tggrdprswdgsveilknwkksglspvrygqcwvfagtlntalrslgipsrvitnfnsah
dtdrnlsvdvyydpmgnpldkgsdsvwnfhvwnegwfvrsdlgpsyggwqvldatpqers
qgvfqcgpasvigvregdvqlnfdmpfifaevnadritwlydnttgkqwknsvnshtigr
yistkavgsnarmdvtdkykypegsdqerqvfqkalgklkpntpfaatssmgleteeqep
siigklkvagmlavgkevnlvlllknlsrdtktvtvnmtawtiiyngtlvhevwkdsatm
sldpeeeaehpikisyaqyerylksdnmiritavckvpdesevvverdiildnptltlev
lnearvrkpvnvqmlfsnpldepvrdcvlmvegsglllgnlkidvptlgpkersrvrfdi
lpsrsgtkqlladfscnkfpaikamlsidvae

    Sequence, based on observed residues (ATOM records): (download) 
    >1nugA (A:)
aalgvqsinwqtafnrqahhtdkfssqelilrrgqnfqvlmimnkglgsnerlefivstg
pypsesamtkavfplsngssggwsavlqasngntltisisspasapigrytmalqifsqg
gissvklgtfillfnpwlnvdsvfmgnhaereeyvqedagiifvgstnrigmigwnfgqf
eedilsiclsildrslnfrrdaatdvasrndpkyvgrvlsaminsnddngvlagnwsgty
tggrdprswdgsveilknwkksglspvrygqcwvfagtlntalrslgipsrvitnfnsah
dtdrnlsvdvyydpmgnpldkgsdsvwnfhvwnegwfvrsdlgpsyggwqvldatpqers
qgvfqcgpasvigvregdvqlnfdmpfifaevnadritwlydnttgkqwknsvnshtigr
yistkavgsnarmdvtdkykypegsdqerqvfqkalgklkpepsiigklkvagmlavgke
vnlvlllknlsrdtktvtvnmtawtiiyngtlvhevwkdsatmsldpeeeaehpikisya
qyerylksdnmiritavckvpdesevvverdiildnptltlevlnearvrkpvnvqmlfs
npldepvrdcvlmvegsglllgnlkidvptlgpkersrvrfdilpsrsgtkqlladfscn
kfpaikamlsidvae

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1nugB (B:)
aalgvqsinwqtafnrqahhtdkfssqelilrrgqnfqvlmimnkglgsnerlefivstg
pypsesamtkavfplsngssggwsavlqasngntltisisspasapigrytmalqifsqg
gissvklgtfillfnpwlnvdsvfmgnhaereeyvqedagiifvgstnrigmigwnfgqf
eedilsiclsildrslnfrrdaatdvasrndpkyvgrvlsaminsnddngvlagnwsgty
tggrdprswdgsveilknwkksglspvrygqcwvfagtlntalrslgipsrvitnfnsah
dtdrnlsvdvyydpmgnpldkgsdsvwnfhvwnegwfvrsdlgpsyggwqvldatpqers
qgvfqcgpasvigvregdvqlnfdmpfifaevnadritwlydnttgkqwknsvnshtigr
yistkavgsnarmdvtdkykypegsdqerqvfqkalgklkpntpfaatssmgleteeqep
siigklkvagmlavgkevnlvlllknlsrdtktvtvnmtawtiiyngtlvhevwkdsatm
sldpeeeaehpikisyaqyerylksdnmiritavckvpdesevvverdiildnptltlev
lnearvrkpvnvqmlfsnpldepvrdcvlmvegsglllgnlkidvptlgpkersrvrfdi
lpsrsgtkqlladfscnkfpaikamlsidvae

    Sequence, based on observed residues (ATOM records): (download) 
    >1nugB (B:)
aalgvqsinwqtafnrqahhtdkfssqelilrrgqnfqvlmimnkglgsnerlefivstg
pypsesamtkavfplsngssggwsavlqasngntltisisspasapigrytmalqifsqg
gissvklgtfillfnpwlnvdsvfmgnhaereeyvqedagiifvgstnrigmigwnfgqf
eedilsiclsildrslnfrrdaatdvasrndpkyvgrvlsaminsnddngvlagnwsgty
tggrdprswdgsveilknwkksglspvrygqcwvfagtlntalrslgipsrvitnfnsah
dtdrnlsvdvyydpmgnpldkgsdsvwnfhvwnegwfvrsdlgpsyggwqvldatpqers
qgvfqcgpasvigvregdvqlnfdmpfifaevnadritwlydnttgkqwknsvnshtigr
yistkavgsnarmdvtdkykypegsdqerqvfqkalgklleteeqepsiigklkvagmla
vgkevnlvlllknlsrdtktvtvnmtawtiiyngtlvhevwkdsatmsldpeeeaehpik
isyaqyerylksdnmiritavckvpdesevvverdiildnptltlevlnearvrkpvnvq
mlfsnpldepvrdcvlmvegsglllgnlkidvptlgpkersrvrfdilpsrsgtkqllad
fscnkfpaikamlsidvae