PDB entry 1hkw

View 1hkw on RCSB PDB site
Description: MYCOBACTERIUM DIAMINOPIMELATE DICARBOXYLASE (LysA)
Class: lyase
Keywords: lyase, decarboxylase, diaminopimelate, dapdc, plp, lysine pathway, mycobacterium tuberculosis, lysine synthetic pathway, psi, protein structure initiative, tb structural genomics consortium, tb, tbsgc
Deposited on 2003-03-11, released 2003-03-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-08-21, with a file datestamp of 2019-08-16.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: diaminopimelate decarboxylase
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed):
    • PDB 1HKW
    • Uniprot P31848 (1-446)
    Domains in SCOPe 2.08: d1hkwa1, d1hkwa2
  • Chain 'B':
    Compound: diaminopimelate decarboxylase
    Species: Mycobacterium tuberculosis [TaxId:83332]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1hkwb1, d1hkwb2
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1hkwA (A:)
mnellhlapnvwprnttrdevgvvciagipltqlaqeygtplfvideddfrsrcretaaa
fgsganvhyaakaflcsevarwiseeglcldvctggelavalhasfpperitlhgnnksv
seltaavkagvghivvdsmteierldaiageagivqdvlvrltvgveahthefistahed
qkfglsvasgaamaavrrvfatdhlrlvglhshigsqifdvdgfelaahrvigllrdvvg
efgpektaqiatvdlggglgisylpsddpppiaelaaklgtivsdestavglptpklvve
pgraiagpgtitlyevgtvkdvdvsatahrryvsvdggmsdnirtalygaqydvrlvsrv
sdappvparlvgkhcesgdiivrdtwvpddirpgdlvavaatgaycyslssrynmvgrpa
vvavhagnarlvlrretvddllslevrhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1hkwA (A:)
nellhlapnvwprnttrdevgvvciagipltqlaqeygtplfvideddfrsrcretaaaf
gsganvhyaakaflcsevarwiseeglcldvctggelavalhasfpperitlhgnnksvs
eltaavkagvghivvdsmteierldaiageagivqdvlvrltvgveahthefistahedq
kfglsvasgaamaavrrvfatdhlrlvglhshigsqifdvdgfelaahrvigllrdvvge
fgpektaqiatvdlggglgisylpsddpppiaelaaklgtivsdestavglptpklvvep
graiagpgtitlyevgtvkdvdvsatahrryvsvdggmsdnirtalygaqydvrlvsrvs
dappvparlvgkhcesgdiivrdtwvpddirpgdlvavaatgaycyslssrynmvgrpav
vavhagnarlvlrretvddllslevr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1hkwB (B:)
mnellhlapnvwprnttrdevgvvciagipltqlaqeygtplfvideddfrsrcretaaa
fgsganvhyaakaflcsevarwiseeglcldvctggelavalhasfpperitlhgnnksv
seltaavkagvghivvdsmteierldaiageagivqdvlvrltvgveahthefistahed
qkfglsvasgaamaavrrvfatdhlrlvglhshigsqifdvdgfelaahrvigllrdvvg
efgpektaqiatvdlggglgisylpsddpppiaelaaklgtivsdestavglptpklvve
pgraiagpgtitlyevgtvkdvdvsatahrryvsvdggmsdnirtalygaqydvrlvsrv
sdappvparlvgkhcesgdiivrdtwvpddirpgdlvavaatgaycyslssrynmvgrpa
vvavhagnarlvlrretvddllslevrhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1hkwB (B:)
ellhlapnvwprnttrdevgvvciagipltqlaqeygtplfvideddfrsrcretaaafg
sganvhyaakaflcsevarwiseeglcldvctggelavalhasfpperitlhgnnksvse
ltaavkagvghivvdsmteierldaiageagivqdvlvrltvgveahthefistahedqk
fglsvasgaamaavrrvfatdhlrlvglhshigsqifdvdgfelaahrvigllrdvvgef
gpektaqiatvdlggglgisylpsddpppiaelaaklgtivsdestavglptpklvvepg
raiagpgtitlyevgtvkdvdvsatahrryvsvdggmsdnirtalygaqydvrlvsrvsd
appvparlvgkhcesgdiivrdtwvpddirpgdlvavaatgaycyslssrynmvgrpavv
avhagnarlvlrretvddllslev