SCOP 1.73: Domain d1nytd1: 1nyt D:102-270

Lineage for d1nytd1 (1nyt D:102-270)

1. Root: SCOP 1.73

2. Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families)

5. Family c.2.1.7: Aminoacid dehydrogenase-like, C-terminal domain [51883] (11 proteins)
   extra N-terminal helix displaces the C-terminal helix (following strand 6) from its usual position creating a family nicotineamide-binding site

6. Protein Shikimate 5-dehydrogenase AroE [89538] (3 species)

7. Species Escherichia coli [TaxId:562] [89539] (1 PDB entry)

8. Domain d1nytd1: 1nyt D:102-270 [86423]
   Other proteins in same PDB: d1nyta2, d1nytb2, d1nytc2, d1nytd2
   complexed with dtt, nap, so4

Details for d1nytd1

PDB Entry: 1nyt, 1.5 Å

PDB Description: shikimate dehydrogenase aroe complexed with nadp+

PDB Compounds: (D:) Shikimate 5-dehydrogenase

SCOP Domain Sequences for d1nytd1:

Sequence; same for both SEQRES and ATOM records:

>d1nytd1 c.2.1.7 (D:102-270) Shikimate 5-dehydrogenase AroE {Escherichia coli [TaxId: 562]}
dgvgllsdlerlsfirpglrilligaggasrgvllpllsldcavtitnrtvsraeelakl
fahtgsiqalsmdeleghefdliinatssgisgdipaipsslihpgiycydmfyqkgktp
flawceqrgskrnadglgmlvaqaahafllwhgvlpdvepvikqlqeel

Timeline for d1nytd1:

• d1nytd1 first appeared in SCOP 1.65
  
• d1nytd1 appears in SCOP 1.71
  
• d1nytd1 appears in SCOP 1.75
  
• d1nytd1 appears in the current release, SCOPe 2.08