SCOPe 2.07: Domain d1k75a_: 1k75 A:

Lineage for d1k75a_ (1k75 A:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.82: ALDH-like [53719] (1 superfamily)
   consists of two similar domains with 3 layers (a/b/a) each; duplication
   core: parallel beta-sheet of 5 strands, order 32145

4. Superfamily c.82.1: ALDH-like [53720] (3 families)
   binds NAD differently from other NAD(P)-dependent oxidoreductases

5. Family c.82.1.2: L-histidinol dehydrogenase HisD [69602] (1 protein)
   automatically mapped to Pfam PF00815

6. Protein L-histidinol dehydrogenase HisD [69603] (1 species)

7. Species Escherichia coli [TaxId:562] [69604] (4 PDB entries)

8. Domain d1k75a_: 1k75 A: [68253]
   complexed with gol, so4

Details for d1k75a_

PDB Entry: 1k75, 1.75 Å

PDB Description: The L-histidinol dehydrogenase (hisD) structure implicates domain swapping and gene duplication.

PDB Compounds: (A:) L-histidinol dehydrogenase

SCOPe Domain Sequences for d1k75a_:

Sequence; same for both SEQRES and ATOM records:

>d1k75a_ c.82.1.2 (A:) L-histidinol dehydrogenase HisD {Escherichia coli [TaxId: 562]}
ntiidwnsctaeqqrqllmrpaisasesitrtvndildnvkargdealreysakfdkttv
talkvsaeeiaaaserlsdelkqamavavknietfhtaqklppvdvetqpgvrcqqvtrp
vasvglyipggsaplfstvlmlatpasiagckkvvlcspppiadeilyaaqlcgvqdvfn
vggaqaiaalafgtesvpkvdkifgpgnafvteakrqvsqrldgaaidmpagpsevlvia
dsgatpdfvasdllsqaehgpdsqvilltpaadmarrvaeaverqlaelpraetarqaln
asrlivtkdlaqcveisnqygpehliiqtrnarelvdsitsagsvflgdwspesagdyas
gtnhvlptygytatcsslgladfqkrmtvqelskegfsalastietlaaaerltahknav
tlrvnalkeqa

Timeline for d1k75a_:

• d1k75a_ first appeared in SCOP 1.59
  
• d1k75a_ appears in SCOPe 2.06
  
• d1k75a_ appears in the current release, SCOPe 2.08