SCOP 1.63: Domain d1e9hc_: 1e9h C:

Lineage for d1e9hc_ (1e9h C:)

1. Root: SCOP 1.63

2. Class d: Alpha and beta proteins (a+b) [53931] (224 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (6 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.1: Serine/threonin kinases [56113] (21 proteins)

6. Protein Cyclin-dependent PK (CDK, different isozymes) [56114] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56115] (47 PDB entries)

8. Domain d1e9hc_: 1e9h C: [64815]
   Other proteins in same PDB: d1e9hb1, d1e9hb2, d1e9hd1, d1e9hd2
   complexed with inr

Details for d1e9hc_

PDB Entry: 1e9h, 2.5 Å

PDB Description: thr 160 phosphorylated cdk2 - human cyclin a3 complex with the inhibitor indirubin-5-sulphonate bound

SCOP Domain Sequences for d1e9hc_:

Sequence; same for both SEQRES and ATOM records:

>d1e9hc_ d.144.1.1 (C:) Cyclin-dependent PK (CDK, different isozymes) {Human (Homo sapiens)}
smenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkeln
hpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafch
shrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgcky
ystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykps
fpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl

Timeline for d1e9hc_:

• d1e9hc_ first appeared in SCOP 1.59
  
• d1e9hc_ appears in SCOP 1.61
  
• d1e9hc_ appears in SCOP 1.65
  
• d1e9hc_ appears in the current release, SCOPe 2.08, called d1e9hc1