SCOP 1.63: Family d.144.1.1: Serine/threonin kinases

Lineage for Family d.144.1.1: Serine/threonin kinases

1. Root: SCOP 1.63

2. Class d: Alpha and beta proteins (a+b) [53931] (224 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (6 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.1: Serine/threonin kinases [56113] (21 proteins)

Proteins:

1. c-jun N-terminal kinase (jnk3s) [56137] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [56138] (1 PDB entry)

2. Calmodulin-dependent protein kinase [56120] (1 species)

   • Species Rat (Rattus norvegicus) [TaxId:10116] [56121] (1 PDB entry)

3. cAMP-dependent PK, catalytic subunit [56116] (4 species)

   1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [64403] (1 PDB entry)

   2. Species Cow (Bos taurus) [TaxId:9913] [56118] (4 PDB entries)

   3. Species Mouse (Mus musculus) [TaxId:10090] [56119] (9 PDB entries)

   4. Species Pig (Sus scrofa) [TaxId:9823] [56117] (3 PDB entries)

4. Casein kinase-1, CK1 [56139] (2 species)

   1. Species Fission yeast (Schizosaccharomyces pombe) [TaxId:4896] [56141] (3 PDB entries)

   2. Species Rat (Rattus norvegicus) [TaxId:10116] [56140] (2 PDB entries)

5. Cell cycle checkpoint kinase chk1 [64404] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [64405] (1 PDB entry)

6. Cyclin-dependent PK (CDK, different isozymes) [56114] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [56115] (47 PDB entries)

7. Death-associated protein kinase, Dak [75560] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [75561] (5 PDB entries)

8. gamma-subunit of glycogen phosphorylase kinase (Phk) [56122] (1 species)

   • Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [56123] (3 PDB entries)

9. Glycogen synthase kinase-3 beta (Gsk3b) [69823] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [69824] (3 PDB entries)

10. MAP kinase activated protein kinase 2, mapkap2 [82789] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [82790] (1 PDB entry)

11. MAP kinase Erk2 [56134] (2 species)

    1. Species Human (Homo sapiens) [TaxId:9606] [56135] (1 PDB entry)

    2. Species Rat (Rattus norvegicus) [TaxId:10116] [56136] (5 PDB entries)

12. MAP kinase p38 [56129] (2 species)

    1. Species Human (Homo sapiens) [TaxId:9606] [56130] (10 PDB entries)

    2. Species Mouse (Mus musculus) [TaxId:10090] [56131] (3 PDB entries)

13. MAP kinase p38-gamma [56132] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [56133] (1 PDB entry)

14. Mycobacterial protein kinase PknB, catalytic domain [82793] (1 species)

    • Species Mycobacterium tuberculosis [TaxId:1773] [82794] (2 PDB entries)

15. pak1 [56146] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [56147] (1 PDB entry)

16. Pkb kinase [82791] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [82792] (2 PDB entries)

17. Protein kinase CK2, alpha subunit [56142] (2 species)

    1. Species Human (Homo sapiens) [TaxId:9606] [75559] (1 PDB entry)

    2. Species Maize (Zea mays) [TaxId:4577] [56143] (9 PDB entries)

18. Sky1p [56148] (1 species)

    • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56149] (1 PDB entry)

19. Titin, kinase domain [56124] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [56125] (1 PDB entry)

20. Twitchin, kinase domain [56126] (2 species)

    1. Species Caenorhabditis elegans, pjk4 [TaxId:6239] [56128] (1 PDB entry)

    2. Species California sea hare (Aplysia californica), twk43 [TaxId:6500] [56127] (1 PDB entry)

21. Type I TGF-beta receptor R4 [56144] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [56145] (2 PDB entries)

More info for Family d.144.1.1: Serine/threonin kinases

Timeline for Family d.144.1.1: Serine/threonin kinases:

• Family d.144.1.1: Serine/threonin kinases first appeared (with stable ids) in SCOP 1.55
  
• Family d.144.1.1: Serine/threonin kinases appears in SCOP 1.61
  
• Family d.144.1.1: Serine/threonin kinases does not appear in SCOP 1.65