SCOP 1.67: Protein: Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain

Lineage for Protein: Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain

Root: SCOP 1.67
Class d: Alpha and beta proteins (a+b) [53931] (260 folds)
Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
contains large mixed beta-sheet
Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (1 family)
Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (3 proteins)
Protein Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain [55841] (2 species)

Species:

Cryptosporidium hominis [TaxId:237895] [100887] (2 PDB entries)
1. Domains for 1j3j:
  1. Domain d1j3jc_: 1j3j C: [84068]
    Other proteins in same PDB: d1j3ja_, d1j3jb_
  2. Domain d1j3jd_: 1j3j D: [84069]
    Other proteins in same PDB: d1j3ja_, d1j3jb_
    complexed with cp6, ndp, ump; mutant
2. Domains for 1qzf:
  1. Domain d1qzfa2: 1qzf A:181-521 [96634]
    Other proteins in same PDB: d1qzfa1, d1qzfb1, d1qzfc1, d1qzfd1, d1qzfe1
  2. Domain d1qzfb2: 1qzf B:181-521 [96636]
    Other proteins in same PDB: d1qzfa1, d1qzfb1, d1qzfc1, d1qzfd1, d1qzfe1
  3. Domain d1qzfc2: 1qzf C:181-521 [96638]
    Other proteins in same PDB: d1qzfa1, d1qzfb1, d1qzfc1, d1qzfd1, d1qzfe1
  4. Domain d1qzfd2: 1qzf D:181-521 [96640]
    Other proteins in same PDB: d1qzfa1, d1qzfb1, d1qzfc1, d1qzfd1, d1qzfe1
  5. Domain d1qzfe2: 1qzf E:181-521 [96642]
    Other proteins in same PDB: d1qzfa1, d1qzfb1, d1qzfc1, d1qzfd1, d1qzfe1
    complexed with cb3, fol, ndp, ump
Malaria parasite (Plasmodium falciparum) [TaxId:5833] [88964] (2 PDB entries)
1. Domains for 1j3i:
  1. Domain d1j3ic_: 1j3i C: [84064]
    Other proteins in same PDB: d1j3ia_, d1j3ib_
  2. Domain d1j3id_: 1j3i D: [84065]
    Other proteins in same PDB: d1j3ia_, d1j3ib_
    complexed with ndp, ump, wra
2. Domains for 1j3k:
  1. Domain d1j3kc_: 1j3k C: [84072]
    Other proteins in same PDB: d1j3ka_, d1j3kb_
  2. Domain d1j3kd_: 1j3k D: [84073]
    Other proteins in same PDB: d1j3ka_, d1j3kb_
    complexed with ndp, ump, wra; mutant

More info for Protein Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain from d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase

Timeline for Protein Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain from d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase:

Protein Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain from d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase first appeared (with stable ids) in SCOP 1.55, called Protein Bifunctional enzyme dihidrofolate reductase-thymidylate synthase, TS domain from d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase
Protein Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain from d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase appears in SCOP 1.65
Protein Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain from d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase appears in SCOP 1.69
Protein Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain from d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase appears in the current release, SCOPe 2.08