SCOP 1.67: Domain d1qzfa2: 1qzf A:181-521

Lineage for d1qzfa2 (1qzf A:181-521)

1. Root: SCOP 1.67

2. Class d: Alpha and beta proteins (a+b) [53931] (260 folds)

3. Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (1 family)

5. Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (3 proteins)

6. Protein Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain [55841] (2 species)

7. Species Cryptosporidium hominis [TaxId:237895] [100887] (2 PDB entries)

8. Domain d1qzfa2: 1qzf A:181-521 [96634]
   Other proteins in same PDB: d1qzfa1, d1qzfb1, d1qzfc1, d1qzfd1, d1qzfe1

Details for d1qzfa2

PDB Entry: 1qzf, 2.8 Å

PDB Description: Crystal structure of DHFR-TS from Cryptosporidium hominis

SCOP Domain Sequences for d1qzfa2:

Sequence; same for both SEQRES and ATOM records:

>d1qzfa2 d.117.1.1 (A:181-521) Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain {Cryptosporidium hominis}
ktlqncdpargqlksiddtvdllgeifgirkmgnrhkfpkeeiyntpsirfgrehyefqy
ldllsrvlengayrenrtgistysifgqmmrfdmresfpllttkkvairsifeeliwfik
gdtngnhliekkvyiwsgngskeyleriglghreendlgpiygfqwrhyngeyktmhddy
tgvgvdqlaklietlknnpkdrrhiltawnpsalsqmalppchvlsqyyvtndnclscnl
yqrscdlglgspfniasyailtmmlaqvcgyepgelaifigdahiyenhltqlkeqlsrt
prpfpqlkfkrkveniedfkwedieligyypyptikmdmav

Timeline for d1qzfa2:

• d1qzfa2 is new in SCOP 1.67
  
• d1qzfa2 appears in SCOP 1.69
  
• d1qzfa2 appears in the current release, SCOPe 2.08