Lineage for Family d.104.1.1: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2532556Fold d.104: Class II aaRS and biotin synthetases [55680] (1 superfamily)
    contains large mixed beta-sheet
  4. 2532557Superfamily d.104.1: Class II aaRS and biotin synthetases [55681] (5 families) (S)
  5. 2532558Family d.104.1.1: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain [55682] (16 protein domains)

Protein Domains:

  1. 2532559Alanyl-tRNA synthetase (AlaRS) [103155] (1 species)
  2. 2532569Asparagine synthetase [55705] (1 species)
  3. 2532575Aspartyl-tRNA synthetase (AspRS) [55696] (5 species)
    1. 2532576Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [55697] (3 PDB entries)
    2. 2532582Species Escherichia coli [TaxId:562] [55699] (3 PDB entries)
    3. 2532589Species Pyrococcus kodakaraensis [TaxId:311400] [55698] (1 PDB entry)
    4. 2532592Species Thermus thermophilus, AspRS-1 [TaxId:274] [55700] (3 PDB entries)
    5. 2532599Species Thermus thermophilus, AspRS-2 [TaxId:274] [90008] (1 PDB entry)
      non-discriminating and archaeal-type enzyme
  4. 2532602ATP phosphoribosyltransferase regulatory subunit HisZ [118058] (2 species)
    shares histidine-binding site with the HisRS catalytic domain
    1. 2532603Species Lactococcus lactis [TaxId:1358] [143639] (2 PDB entries)
      Uniprot Q02147 6-323
    2. 2532612Species Thermotoga maritima [TaxId:2336] [118059] (1 PDB entry)
      Uniprot Q9X0D3
  5. 2532617Glycyl-tRNA synthetase (GlyRS) [55692] (1 species)
  6. 2532625Glycyl-tRNA synthetase (GlyRS) alpha chain [75504] (1 species)
  7. 2532629Histidyl-tRNA synthetase (HisRS) [55688] (4 species)
    1. 2532630Species Escherichia coli [TaxId:562] [55689] (4 PDB entries)
    2. 2532647Species Staphylococcus aureus [TaxId:1280] [55690] (1 PDB entry)
    3. 2532650Species Thermoplasma acidophilum [TaxId:2303] [143637] (1 PDB entry)
      Uniprot Q9HLX5 3-329
    4. 2532653Species Thermus thermophilus [TaxId:274] [55691] (3 PDB entries)
  8. 2532663Hypothetical protein PF1951 [103157] (1 species)
  9. 2532666Lysyl-tRNA synthetase (LysRS) [55685] (3 species)
    contains an insertion of LEM/SAP-like HeH motif, residues 337-379
    1. 2532667Species Escherichia coli, gene lysS [TaxId:562] [55687] (2 PDB entries)
    2. 2532670Species Escherichia coli, gene lysU [TaxId:562] [55686] (5 PDB entries)
    3. 2532678Species Geobacillus stearothermophilus [TaxId:1422] [225969] (1 PDB entry)
  10. 2532683Phenyl-tRNA synthetase (PheRS) alpha subunit, PheS [55701] (1 species)
  11. 2532697Phenyl-tRNA synthetase (PheRS) beta subunit, PheT, central domain [55703] (1 species)
    this domain is non-catalytic
  12. 2532711Prolyl-tRNA synthetase (ProRS) [64347] (3 species)
    1. 2532712Species Methanocaldococcus jannaschii [TaxId:2190] [90010] (1 PDB entry)
    2. 2532717Species Methanothermobacter thermautotrophicus [TaxId:145262] [90009] (4 PDB entries)
    3. 2532722Species Thermus thermophilus [TaxId:274] [64348] (4 PDB entries)
  13. 2532735Seryl-tRNA synthetase (SerRS) [55683] (1 species)
  14. 2532745The aaRS-like accessory subunit of mitochondrial polymerase gamma, N-terminal domain [64349] (2 species)
    1. 2532746Species Human (Homo sapiens) [TaxId:9606] [143638] (1 PDB entry)
      Uniprot Q9UHN1 66-355
    2. 2532751Species Mouse (Mus musculus) [TaxId:10090] [64350] (2 PDB entries)
  15. 2532760Threonyl-tRNA synthetase (ThrRS) [55694] (2 species)
    1. 2532761Species Escherichia coli [TaxId:562] [55695] (5 PDB entries)
    2. 2532779Species Staphylococcus aureus [TaxId:1280] [103154] (2 PDB entries)
  16. 2532784automated matches [193659] (6 species)
    not a true protein
    1. 2532785Species Aquifex aeolicus [TaxId:224324] [317216] (1 PDB entry)
    2. 2532791Species Campylobacter jejuni [TaxId:197] [256056] (2 PDB entries)
    3. 2532796Species Campylobacter jejuni [TaxId:354242] [256055] (1 PDB entry)
    4. 2532799Species Escherichia coli K-12 [TaxId:83333] [227935] (6 PDB entries)
    5. 2532812Species Pyrococcus abyssi [TaxId:29292] [193660] (6 PDB entries)
    6. 2532825Species Trypanosoma brucei [TaxId:999953] [237835] (1 PDB entry)

More info for Family d.104.1.1: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain

Timeline for Family d.104.1.1: Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain: