Lineage for Family d.96.1.1: GTP cyclohydrolase I

  1. Root: SCOPe 2.08
  2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. Fold d.96: T-fold [55619] (2 superfamilies)
    beta(2)-alpha(2)-beta(2); 2 layers: alpha/beta; antiparallel sheet 1234
    tunnel-shaped: its known members form wide oligomeric barrels different sizes
  4. Superfamily d.96.1: Tetrahydrobiopterin biosynthesis enzymes-like [55620] (5 families) (S)
    bind purine or pterin in topologically similar sites between subunits
  5. Family d.96.1.1: GTP cyclohydrolase I [55621] (2 proteins)

Proteins:

  1. GTP cyclohydrolase I [55622] (4 species)
    beta-sheets of five subunits form a barrel, closed: n=20, S=20
    1. Species Escherichia coli [TaxId:562] [55623] (7 PDB entries)
    2. Species Human (Homo sapiens) [TaxId:9606] [55624] (1 PDB entry)
    3. Species Norway rat (Rattus norvegicus) [TaxId:10116] [69790] (3 PDB entries)
      Uniprot P22288
    4. Species Thermus thermophilus [TaxId:274] [143627] (3 PDB entries)
      Uniprot Q5SH52 32-216
  2. automated matches [195794] (2 species)
    not a true protein
    1. Species Human (Homo sapiens) [TaxId:9606] [396510] (6 PDB entries)
    2. Species Yersinia pseudotuberculosis [TaxId:214092] [195796] (1 PDB entry)

More info for Family d.96.1.1: GTP cyclohydrolase I

Timeline for Family d.96.1.1: GTP cyclohydrolase I: