Lineage for Family d.19.1.1: MHC antigen-recognition domain

  1. Root: SCOPe 2.08
  2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. Fold d.19: MHC antigen-recognition domain [54451] (1 superfamily)
    dimeric
  4. Superfamily d.19.1: MHC antigen-recognition domain [54452] (2 families) (S)
  5. Family d.19.1.1: MHC antigen-recognition domain [54453] (13 proteins)

Proteins:

  1. CD1, alpha-1 and alpha-2 domains [54456] (5 species)
    Class I MHC-related
    1. Species Cow (Bos taurus) [TaxId:9913] [226526] (2 PDB entries)
    2. Species Human (Homo sapiens), CD1a [TaxId:9606] [102838] (15 PDB entries)
    3. Species Human (Homo sapiens), CD1b [TaxId:9606] [75378] (17 PDB entries)
    4. Species Human (Homo sapiens), CD1d [TaxId:9606] [160079] (2 PDB entries)
      Uniprot P15813 24-201
    5. Species Mouse (Mus musculus) [TaxId:10090] [54457] (25 PDB entries)
  2. Class I MHC homolog [54489] (4 species)
    gamma, delta T-cell ligand
    1. Species Human (Homo sapiens), Mic-a [TaxId:9606] [54490] (2 PDB entries)
    2. Species Human (Homo sapiens), Mic-b [TaxId:9606] [75380] (1 PDB entry)
    3. Species Mouse (Mus musculus), t10 [TaxId:10090] [102839] (1 PDB entry)
    4. Species Mouse (Mus musculus), t22 [TaxId:10090] [54491] (2 PDB entries)
  3. Class I MHC, alpha-1 and alpha-2 domains [54468] (29 species)
    1. Species Human (Homo sapiens) [TaxId:9606] [361260] (1 PDB entry)
    2. Species Human (Homo sapiens), HLA-A1 [TaxId:9606] [117849] (2 PDB entries)
      Uniprot P30443 25-298 # 1A01_HUMAN HLA class I histocompatibility antigen, A-1 alpha chain precursor
    3. Species Human (Homo sapiens), HLA-A11 [TaxId:9606] [110840] (4 PDB entries)
      Uniprot P13746 25-299 # 1A11_HUMAN HLA class I histocompatibility antigen, A-11 alpha chain precursor
    4. Species Human (Homo sapiens), HLA-A2 [TaxId:9606] [54469] (9 PDB entries)
    5. Species Human (Homo sapiens), HLA-A2.1 [TaxId:9606] [54470] (104 PDB entries)
      Uniprot P01892 25-298
    6. Species Human (Homo sapiens), HLA-AW68 [TaxId:9606] [54472] (4 PDB entries)
    7. Species Human (Homo sapiens), HLA-B08 [TaxId:9606] [54473] (7 PDB entries)
    8. Species Human (Homo sapiens), HLA-B27 [TaxId:9606] [54471] (9 PDB entries)
      Uniprot P03989 25-300
    9. Species Human (Homo sapiens), HLA-B35 [TaxId:9606] [54475] (15 PDB entries)
      Uniprot P30685 25-300
    10. Species Human (Homo sapiens), HLA-B51 [TaxId:9606] [54476] (3 PDB entries)
    11. Species Human (Homo sapiens), HLA-B53 [TaxId:9606] [54474] (23 PDB entries)
    12. Species Human (Homo sapiens), HLA-BW44 [TaxId:9606] [102837] (19 PDB entries)
      Uniprot P30481 25-300
    13. Species Human (Homo sapiens), HLA-CW3 [TaxId:9606] [54477] (2 PDB entries)
    14. Species Human (Homo sapiens), HLA-CW4 [TaxId:9606] [54478] (2 PDB entries)
    15. Species Human (Homo sapiens), HLA-E [TaxId:9606] [54479] (8 PDB entries)
    16. Species Human (Homo sapiens), HLA-G [TaxId:9606] [160076] (3 PDB entries)
      Uniprot P17693 25-205! Uniprot P17693 26-205
    17. Species Mouse (Mus musculus) [TaxId:10090] [226600] (3 PDB entries)
    18. Species Mouse (Mus musculus), H-2DB [TaxId:10090] [54482] (28 PDB entries)
    19. Species Mouse (Mus musculus), H-2DD [TaxId:10090] [54485] (23 PDB entries)
    20. Species Mouse (Mus musculus), H-2KB [TaxId:10090] [54481] (52 PDB entries)
      Uniprot P01901 22-299
    21. Species Mouse (Mus musculus), H-2KD [TaxId:10090] [160078] (4 PDB entries)
      Uniprot P01902 22-202
    22. Species Mouse (Mus musculus), H-2KK [TaxId:10090] [160075] (2 PDB entries)
      Uniprot P04223 22-197
    23. Species Mouse (Mus musculus), H-2LD [TaxId:10090] [54484] (2 PDB entries)
    24. Species Mouse (Mus musculus), H-2M10 [TaxId:10090] [160077] (2 PDB entries)
    25. Species Mouse (Mus musculus), H-2M3 [TaxId:10090] [54483] (1 PDB entry)
    26. Species Mouse (Mus musculus), IB QA-2 [TaxId:10090] [69680] (1 PDB entry)
    27. Species Mouse (Mus musculus), tla(c), H-2 class [TaxId:10090] [89861] (1 PDB entry)
    28. Species Norway rat (Rattus norvegicus), RT1-AA [TaxId:10116] [54486] (3 PDB entries)
    29. Species Rhesus monkey (Macaca mulatta) [TaxId:9544] [160074] (1 PDB entry)
  4. Class I MHC-related molecule Ulbp3 [69681] (1 species)
  5. Class II MHC alpha chain, N-terminal domain [88806] (15 species)
    1. Species Human (Homo sapiens), HLA-DM [TaxId:9606] [88807] (1 PDB entry)
    2. Species Human (Homo sapiens), HLA-DQ2 [TaxId:9606] [102833] (1 PDB entry)
    3. Species Human (Homo sapiens), HLA-DQ6 [TaxId:9606] [102834] (1 PDB entry)
    4. Species Human (Homo sapiens), HLA-DQ8 [TaxId:9606] [88812] (1 PDB entry)
    5. Species Human (Homo sapiens), HLA-DR1 [TaxId:9606] [88808] (18 PDB entries)
      Uniprot P01903 28-207
    6. Species Human (Homo sapiens), HLA-DR2 [TaxId:9606] [88809] (13 PDB entries)
    7. Species Human (Homo sapiens), HLA-DR3 [TaxId:9606] [88810] (1 PDB entry)
    8. Species Human (Homo sapiens), HLA-DR4 [TaxId:9606] [88811] (5 PDB entries)
    9. Species Mouse (Mus musculus), H2-DM [TaxId:10090] [88818] (1 PDB entry)
    10. Species Mouse (Mus musculus), I-A(G7) [TaxId:10090] [88817] (4 PDB entries)
    11. Species Mouse (Mus musculus), I-AB [TaxId:10090] [88815] (4 PDB entries)
    12. Species Mouse (Mus musculus), I-AD [TaxId:10090] [88816] (2 PDB entries)
    13. Species Mouse (Mus musculus), I-AK [TaxId:10090] [88813] (7 PDB entries)
    14. Species Mouse (Mus musculus), I-AU [TaxId:10090] [89859] (13 PDB entries)
    15. Species Mouse (Mus musculus), I-EK [TaxId:10090] [88814] (9 PDB entries)
  6. Class II MHC beta chain, N-terminal domain [88819] (15 species)
    1. Species Human (Homo sapiens), HLA-DM [TaxId:9606] [88820] (1 PDB entry)
    2. Species Human (Homo sapiens), HLA-DQ2 [TaxId:9606] [102835] (1 PDB entry)
    3. Species Human (Homo sapiens), HLA-DQ6 [TaxId:9606] [102836] (1 PDB entry)
    4. Species Human (Homo sapiens), HLA-DQ8 [TaxId:9606] [88825] (1 PDB entry)
    5. Species Human (Homo sapiens), HLA-DR1 [TaxId:9606] [88821] (20 PDB entries)
    6. Species Human (Homo sapiens), HLA-DR2 [TaxId:9606] [88822] (13 PDB entries)
      Uniprot P04229 30-219
    7. Species Human (Homo sapiens), HLA-DR3 [TaxId:9606] [88823] (1 PDB entry)
    8. Species Human (Homo sapiens), HLA-DR4 [TaxId:9606] [88824] (9 PDB entries)
    9. Species Mouse (Mus musculus), H2-DM [TaxId:10090] [88831] (1 PDB entry)
    10. Species Mouse (Mus musculus), I-A(G7) [TaxId:10090] [88830] (4 PDB entries)
    11. Species Mouse (Mus musculus), I-AB [TaxId:10090] [88828] (6 PDB entries)
    12. Species Mouse (Mus musculus), I-AD [TaxId:10090] [88829] (2 PDB entries)
    13. Species Mouse (Mus musculus), I-AK [TaxId:10090] [88826] (3 PDB entries)
    14. Species Mouse (Mus musculus), I-AU [TaxId:10090] [89860] (2 PDB entries)
    15. Species Mouse (Mus musculus), I-EK [TaxId:10090] [88827] (10 PDB entries)
  7. Endothelial protein C receptor [75381] (1 species)
    phospholipid-binding protein
  8. Fc (IgG) receptor, alpha-1 and alpha-2 domains [54454] (2 species)
    class I MHC-related
    1. Species Human (Homo sapiens) [TaxId:9606] [54493] (1 PDB entry)
    2. Species Norway rat (Rattus norvegicus) [TaxId:10116] [54455] (3 PDB entries)
  9. Hemochromatosis protein Hfe, alpha-1 and alpha-2 domains [88832] (1 species)
  10. Immunomodulatory protein m144, alpha-1 and alpha-2 domains [110841] (1 species)
  11. NK cell ligand RAE-1 beta [69683] (1 species)
  12. Zinc-alpha-2-glycoprotein, ZAG [54487] (1 species)
    fat depleting factor related to class I MHC
  13. automated matches [191280] (6 species)
    not a true protein
    1. Species Ailuropoda melanoleuca [TaxId:9646] [405006] (1 PDB entry)
    2. Species Cat (Felis catus) [TaxId:9685] [342902] (2 PDB entries)
    3. Species Cow (Bos taurus) [TaxId:9913] [225910] (2 PDB entries)
    4. Species Human (Homo sapiens) [TaxId:9606] [189896] (31 PDB entries)
    5. Species Rhesus monkey (Macaca mulatta) [TaxId:9544] [384001] (4 PDB entries)
    6. Species Mouse (Mus musculus) [TaxId:10090] [225821] (8 PDB entries)

More info for Family d.19.1.1: MHC antigen-recognition domain

Timeline for Family d.19.1.1: MHC antigen-recognition domain: