Lineage for Family d.9.1.1: Interleukin 8-like chemokines

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2156493Fold d.9: IL8-like [54116] (2 superfamilies)
    beta(3)-alpha
  4. 2156494Superfamily d.9.1: Interleukin 8-like chemokines [54117] (2 families) (S)
    form dimers with different dimerisation modes
  5. 2156495Family d.9.1.1: Interleukin 8-like chemokines [54118] (25 protein domains)

Protein Domains:

  1. 2156496CC chemokine I-309 [54138] (1 species)
  2. 2156499Chemokine domain of fractalkine [54146] (1 species)
  3. 2156506Chemokine hcc-2 (macrophage inflammatory protein-5) [54154] (1 species)
  4. 2156509Eotaxin [54140] (1 species)
  5. 2156513Eotaxin-2 [54142] (1 species)
  6. 2156517Eotaxin-3 [75341] (1 species)
  7. 2156521Gro beta [54156] (1 species)
  8. 2156525IL-8/MGSA chimeric protein CIL-8M [54126] (1 species)
    IL-8: residues 1-53; MGSA: residues 54-72
  9. 2156529Interleukin-8, IL-8 [54119] (1 species)
  10. 2156550IP-10/CXCL10 [82573] (1 species)
  11. 2156561Lymphotactin [69632] (1 species)
  12. 2156565Macrophage inflammatory protein, MIP [54128] (5 species)
    has different dimerisation mode
    1. 2156566Species Human (Homo sapiens), 1-alpha [TaxId:9606] [54130] (3 PDB entries)
    2. 2156589Species Human (Homo sapiens), 1-beta [TaxId:9606] [54129] (6 PDB entries)
    3. 2156602Species Human (Homo sapiens), ccl20/mip-3a [TaxId:9606] [75340] (3 PDB entries)
    4. 2156608Species Kaposi's sarcoma-associated herpesvirus, VMIP-II [TaxId:37296] [54131] (7 PDB entries)
      anti-HIV chemokine
    5. 2156620Species Mouse (Mus musculus), ccl20/mip-3a [TaxId:10090] [64214] (1 PDB entry)
  13. 2156622Macrophage inflammatory protein-2 [54152] (1 species)
  14. 2156630Melanoma growth stimulating activity (MGSA) [54124] (1 species)
  15. 2156638Monocyte chemoattractant protein-1 (MCP-1, MCAF) [54134] (1 species)
  16. 2156649Monocyte chemoattractant protein-2 (MCP-2) [54136] (1 species)
  17. 2156652Monocyte chemoattractant protein-3 (MCP-3) [54144] (1 species)
  18. 2156657Myeloid progenitor inhibitory factor-1 (MPIF-1) [64215] (1 species)
  19. 2156660Platelet basic protein, PBP [54148] (1 species)
    synonym: Small inducible cytokine B7; Neutrophil-activating peptide-2 (NAP-2), Connective tissue activating peptide-III (CTAP-III)
  20. 2156671Platelet factor 4, PF4 [54121] (2 species)
    1. 2156672Species Cow (Bos taurus) [TaxId:9913] [54122] (1 PDB entry)
    2. 2156677Species Human (Homo sapiens) [TaxId:9606] [54123] (6 PDB entries)
  21. 2156702RANTES (regulated upon activation, normal T-cell expressed and secreted) [54132] (1 species)
    has different dimerisation mode
  22. 2156728Small inducible cytokine b11 (CXCL11/I-TAC) [102732] (1 species)
  23. 2156731Stromal cell-derived factor-1 (SDF-1) [54150] (1 species)
  24. 2156771Thymus and activation-regulated chemokine, TRAC [102730] (1 species)
  25. 2156783automated matches [190403] (3 species)
    not a true protein
    1. 2156784Species Human (Homo sapiens) [TaxId:9606] [187277] (22 PDB entries)
    2. 2156825Species Human herpesvirus 8 strain gk18 [TaxId:868565] [269363] (1 PDB entry)
    3. 2156827Species Mouse (Mus musculus) [TaxId:10090] [188560] (1 PDB entry)

More info for Family d.9.1.1: Interleukin 8-like chemokines

Timeline for Family d.9.1.1: Interleukin 8-like chemokines: