Lineage for Family d.9.1.1: Interleukin 8-like chemokines

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2499233Fold d.9: IL8-like [54116] (2 superfamilies)
    beta(3)-alpha
  4. 2499234Superfamily d.9.1: Interleukin 8-like chemokines [54117] (2 families) (S)
    form dimers with different dimerisation modes
  5. 2499235Family d.9.1.1: Interleukin 8-like chemokines [54118] (25 protein domains)

Protein Domains:

  1. 2499236CC chemokine I-309 [54138] (1 species)
  2. 2499239Chemokine domain of fractalkine [54146] (1 species)
  3. 2499246Chemokine hcc-2 (macrophage inflammatory protein-5) [54154] (1 species)
  4. 2499249Eotaxin [54140] (1 species)
  5. 2499253Eotaxin-2 [54142] (1 species)
  6. 2499257Eotaxin-3 [75341] (1 species)
  7. 2499261Gro beta [54156] (1 species)
  8. 2499265IL-8/MGSA chimeric protein CIL-8M [54126] (1 species)
    IL-8: residues 1-53; MGSA: residues 54-72
  9. 2499269Interleukin-8, IL-8 [54119] (1 species)
  10. 2499291IP-10/CXCL10 [82573] (1 species)
  11. 2499302Lymphotactin [69632] (1 species)
  12. 2499306Macrophage inflammatory protein, MIP [54128] (5 species)
    has different dimerisation mode
    1. 2499307Species Human (Homo sapiens), 1-alpha [TaxId:9606] [54130] (3 PDB entries)
    2. 2499330Species Human (Homo sapiens), 1-beta [TaxId:9606] [54129] (6 PDB entries)
    3. 2499343Species Human (Homo sapiens), ccl20/mip-3a [TaxId:9606] [75340] (3 PDB entries)
    4. 2499349Species Kaposi's sarcoma-associated herpesvirus, VMIP-II [TaxId:37296] [54131] (7 PDB entries)
      anti-HIV chemokine
    5. 2499361Species Mouse (Mus musculus), ccl20/mip-3a [TaxId:10090] [64214] (1 PDB entry)
  13. 2499363Macrophage inflammatory protein-2 [54152] (1 species)
  14. 2499371Melanoma growth stimulating activity (MGSA) [54124] (1 species)
  15. 2499379Monocyte chemoattractant protein-1 (MCP-1, MCAF) [54134] (1 species)
  16. 2499390Monocyte chemoattractant protein-2 (MCP-2) [54136] (1 species)
  17. 2499393Monocyte chemoattractant protein-3 (MCP-3) [54144] (1 species)
  18. 2499398Myeloid progenitor inhibitory factor-1 (MPIF-1) [64215] (1 species)
  19. 2499401Platelet basic protein, PBP [54148] (1 species)
    synonym: Small inducible cytokine B7; Neutrophil-activating peptide-2 (NAP-2), Connective tissue activating peptide-III (CTAP-III)
  20. 2499412Platelet factor 4, PF4 [54121] (2 species)
    1. 2499413Species Cow (Bos taurus) [TaxId:9913] [54122] (1 PDB entry)
    2. 2499418Species Human (Homo sapiens) [TaxId:9606] [54123] (6 PDB entries)
  21. 2499443RANTES (regulated upon activation, normal T-cell expressed and secreted) [54132] (1 species)
    has different dimerisation mode
  22. 2499496Small inducible cytokine b11 (CXCL11/I-TAC) [102732] (1 species)
  23. 2499499Stromal cell-derived factor-1 (SDF-1) [54150] (1 species)
  24. 2499540Thymus and activation-regulated chemokine, TRAC [102730] (1 species)
  25. 2499552automated matches [190403] (3 species)
    not a true protein
    1. 2499553Species Human (Homo sapiens) [TaxId:9606] [187277] (22 PDB entries)
    2. 2499616Species Human herpesvirus 8 strain gk18 [TaxId:868565] [269363] (1 PDB entry)
    3. 2499618Species Mouse (Mus musculus) [TaxId:10090] [188560] (1 PDB entry)

More info for Family d.9.1.1: Interleukin 8-like chemokines

Timeline for Family d.9.1.1: Interleukin 8-like chemokines: