SCOP 1.63: Superfamily d.3.1: Cysteine proteinases

Lineage for Superfamily d.3.1: Cysteine proteinases

1. Root: SCOP 1.63

2. Class d: Alpha and beta proteins (a+b) [53931] (224 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (9 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

Families:

1. d.3.1.1: Papain-like [54002] (19 proteins)

2. d.3.1.2: FMDV leader protease [54037] (1 protein)

3. d.3.1.3: Calpain large subunit, catalytic domain (domain II) [54040] (1 protein)

4. d.3.1.4: Transglutaminase catalytic domain [54044] (1 protein)

5. d.3.1.5: Arylamine N-acetyltransferase [54047] (1 protein)
   fold similar to that of the factor XIII catalytic domain

6. d.3.1.6: Ubiquitin carboxyl-terminal hydrolase UCH-l3 [54050] (1 protein)

7. d.3.1.7: Adenoviral protease-like [54054] (2 proteins)

8. d.3.1.8: Microbial transglutaminase [75336] (1 protein)
   inverted positions of the catalytic triad Asp and His residues

9. d.3.1.9: Ubiquitin carboxyl-terminal hydrolase 7 (USP7, HAUSP) [82568] (1 protein)

More info for Superfamily d.3.1: Cysteine proteinases

Timeline for Superfamily d.3.1: Cysteine proteinases:

• Superfamily d.3.1: Cysteine proteinases first appeared (with stable ids) in SCOP 1.55
  
• Superfamily d.3.1: Cysteine proteinases appears in SCOP 1.61
  
• Superfamily d.3.1: Cysteine proteinases appears in SCOP 1.65
  
• Superfamily d.3.1: Cysteine proteinases appears in the current release, SCOPe 2.08