Lineage for Superfamily d.3.1: Cysteine proteinases

  1. Root: SCOP 1.65
  2. 323018Class d: Alpha and beta proteins (a+b) [53931] (234 folds)
  3. 324261Fold d.3: Cysteine proteinases [54000] (1 superfamily)
    consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn
  4. 324262Superfamily d.3.1: Cysteine proteinases [54001] (9 families) (S)
    the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

Families:

  1. 324263d.3.1.1: Papain-like [54002] (20 proteins)
  2. 324434d.3.1.2: FMDV leader protease [54037] (1 protein)
  3. 324448d.3.1.3: Calpain large subunit, catalytic domain (domain II) [54040] (1 protein)
  4. 324460d.3.1.4: Transglutaminase catalytic domain [54044] (1 protein)
  5. 324496d.3.1.5: Arylamine N-acetyltransferase [54047] (1 protein)
    fold similar to that of the factor XIII catalytic domain
  6. 324512d.3.1.6: Ubiquitin carboxyl-terminal hydrolase UCH-l3 [54050] (1 protein)
  7. 324519d.3.1.7: Adenoviral protease-like [54054] (2 proteins)
  8. 324526d.3.1.8: Microbial transglutaminase [75336] (1 protein)
    inverted positions of the catalytic triad Asp and His residues
  9. 324533d.3.1.9: Ubiquitin carboxyl-terminal hydrolase 7 (USP7, HAUSP) [82568] (1 protein)

More info for Superfamily d.3.1: Cysteine proteinases

Timeline for Superfamily d.3.1: Cysteine proteinases: