SCOPe 2.03: Protein: Acetylcholinesterase

Lineage for Protein: Acetylcholinesterase

Root: SCOPe 2.03
Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest
Superfamily c.69.1: alpha/beta-Hydrolases [53474] (42 families)
many members have left-handed crossover connection between strand 8 and additional strand 9
Family c.69.1.1: Acetylcholinesterase-like [53475] (6 proteins)
automatically mapped to Pfam PF00135
Protein Acetylcholinesterase [53476] (5 species)

Species:

Electric eel (Electrophorus electricus) [TaxId:8005] [53478] (3 PDB entries)
1. Domain for 1c2b:
  - Domain d1c2ba_: 1c2b A: [34614]
2. Domains for 1c2o:
  1. Domain d1c2oa_: 1c2o A: [34610]
  2. Domain d1c2ob_: 1c2o B: [34611]
  3. Domain d1c2oc_: 1c2o C: [34612]
  4. Domain d1c2od_: 1c2o D: [34613]
3. Domain for 1eea:
  - Domain d1eeaa_: 1eea A: [34609]
Fruit fly (Drosophila melanogaster) [TaxId:7227] [53481] (3 PDB entries)
1. Domain for 1dx4:
  - Domain d1dx4a_: 1dx4 A: [34622]
    complexed with 760, nag, so4
2. Domain for 1qo9:
  - Domain d1qo9a_: 1qo9 A: [34624]
    complexed with nag
3. Domain for 1qon:
  - Domain d1qona_: 1qon A: [34623]
    complexed with i40, so4
Human (Homo sapiens) [TaxId:9606] [53480] (9 PDB entries)
1. Domain for 1b41:
  - Domain d1b41a_: 1b41 A: [34621]
    Other proteins in same PDB: d1b41b_
    complexed with ndg
2. Domain for 1f8u:
  - Domain d1f8ua_: 1f8u A: [34620]
    Other proteins in same PDB: d1f8ub_
    mutant
3. Domains for 4ey4:
  1. Domain d4ey4a_: 4ey4 A: [194513]
    automated match to d1maac_
    complexed with edo, nag, no3, pe8
  2. Domain d4ey4b_: 4ey4 B: [194514]
    automated match to d1maac_
    complexed with edo, nag, no3, pe8
4. Domains for 4ey5:
  1. Domain d4ey5a_: 4ey5 A: [194518]
    automated match to d1maac_
    complexed with dms, edo, hup, nag, no3
  2. Domain d4ey5b_: 4ey5 B: [194517]
    automated match to d1maac_
    complexed with dms, edo, hup, nag, no3
5. Domains for 4ey6:
  1. Domain d4ey6a_: 4ey6 A: [194511]
    automated match to d1maac_
    complexed with edo, gnt, nag, no3, pe8
  2. Domain d4ey6b_: 4ey6 B: [194510]
    automated match to d1maac_
    complexed with edo, gnt, nag, no3, pe8
6. Domains for 4ey7:
  1. Domain d4ey7a_: 4ey7 A: [194515]
    automated match to d1maac_
    complexed with e20, edo, nag, no3
  2. Domain d4ey7b_: 4ey7 B: [194516]
    automated match to d1maac_
    complexed with e20, edo, nag, no3
7. Domain for 4ey8:
  - Domain d4ey8a_: 4ey8 A: [194512]
    Other proteins in same PDB: d4ey8b_
    automated match to d1maac_
    complexed with nag, so4
8. Domains for 4m0e:
  1. Domain d4m0ea_: 4m0e A: [228381]
    automated match to d4ey6b_
    complexed with 1yl, edo, nag, no3
  2. Domain d4m0eb_: 4m0e B: [228383]
    automated match to d4ey6b_
    complexed with 1yl, edo, nag, no3
9. Domains for 4m0f:
  1. Domain d4m0fa_: 4m0f A: [228384]
    automated match to d4ey6b_
    complexed with 1yk, edo, nag, no3
  2. Domain d4m0fb_: 4m0f B: [228385]
    automated match to d4ey6b_
    complexed with 1yk, edo, nag, no3
Mouse (Mus musculus) [TaxId:10090] [53479] (17 PDB entries)
1. Domains for 1j06:
  1. Domain d1j06a_: 1j06 A: [77021]
    complexed with ae3, co3, nag, p6g, pg4
  2. Domain d1j06b_: 1j06 B: [77022]
    complexed with ae3, co3, nag, p6g, pg4
2. Domains for 1j07:
  1. Domain d1j07a_: 1j07 A: [77023]
    complexed with cl, co3, dcu, nag, p6g, pg4
  2. Domain d1j07b_: 1j07 B: [77024]
    complexed with cl, co3, dcu, nag, p6g, pg4
3. Domain for 1ku6:
  - Domain d1ku6a_: 1ku6 A: [91037]
    Other proteins in same PDB: d1ku6b_
    complexed with edo, nag
4. Domains for 1maa:
  1. Domain d1maaa_: 1maa A: [34615]
    complexed with dme, gol, nag, po4
  2. Domain d1maab_: 1maa B: [34616]
    complexed with dme, gol, nag, po4
  3. Domain d1maac_: 1maa C: [34617]
    complexed with dme, gol, nag, po4
  4. Domain d1maad_: 1maa D: [34618]
    complexed with dme, gol, nag, po4
5. Domain for 1mah:
  - Domain d1maha_: 1mah A: [34619]
    Other proteins in same PDB: d1mahf_
    complexed with nag
6. Domains for 1n5m:
  1. Domain d1n5ma_: 1n5m A: [80031]
    complexed with co3, gmn, iod, nag, p6g, pg4
  2. Domain d1n5mb_: 1n5m B: [80032]
    complexed with co3, gmn, iod, nag, p6g, pg4
7. Domains for 1n5r:
  1. Domain d1n5ra_: 1n5r A: [80037]
    complexed with acy, nag, p6g, pg4, prm
  2. Domain d1n5rb_: 1n5r B: [80038]
    complexed with acy, nag, p6g, pg4, prm
8. Domains for 1q83:
  1. Domain d1q83a_: 1q83 A: [96154]
    complexed with nag, p6g, tz5
  2. Domain d1q83b_: 1q83 B: [96155]
    complexed with nag, p6g, tz5
9. Domains for 1q84:
  1. Domain d1q84a_: 1q84 A: [96156]
    complexed with nag, p6g, tz4
  2. Domain d1q84b_: 1q84 B: [96157]
    complexed with nag, p6g, tz4
10. Domains for 2gyu:
  1. Domain d2gyua_: 2gyu A: [135873]
    automated match to d1maac_
    complexed with hi6, nag, p4g, p6g
  2. Domain d2gyub_: 2gyu B: [135874]
    automated match to d1maac_
    complexed with hi6, nag, p4g, p6g
11. Domains for 2gyv:
  1. Domain d2gyva_: 2gyv A: [135875]
    automated match to d1maac_
    complexed with co3, hbp, nag, p3g
  2. Domain d2gyvb_: 2gyv B: [135876]
    automated match to d1maac_
    complexed with co3, hbp, nag, p3g
12. Domains for 2gyw:
  1. Domain d2gywa_: 2gyw A: [135877]
    automated match to d1maac_
    complexed with co3, nag, obi, p6g
  2. Domain d2gywb_: 2gyw B: [135878]
    automated match to d1maac_
    complexed with co3, nag, obi, p6g
13. Domains for 3dl4:
  1. Domain d3dl4a_: 3dl4 A: [174045]
    automated match to d1maac_
    complexed with p6g
  2. Domain d3dl4b_: 3dl4 B: [174046]
    automated match to d1maac_
    complexed with p6g
14. Domains for 3dl7:
  1. Domain d3dl7a_: 3dl7 A: [174047]
    automated match to d1maac_
    complexed with cl, nag, p6g, pg4
  2. Domain d3dl7b_: 3dl7 B: [174048]
    automated match to d1maac_
    complexed with cl, nag, p6g, pg4
15. Domains for 3zlv:
  1. Domain d3zlva_: 3zlv A: [192674]
    automated match to d1maac_
    complexed with 1ka, co3, hi6, pe4
  2. Domain d3zlvb_: 3zlv B: [192912]
    automated match to d1maac_
    complexed with 1ka, co3, hi6, pe4
16. Domains for 4bc1:
  1. Domain d4bc1a_: 4bc1 A: [192858]
    automated match to d1maac_
    complexed with cl, nag, so4, tqv
  2. Domain d4bc1b_: 4bc1 B: [192856]
    automated match to d1maac_
    complexed with cl, nag, so4, tqv
  3. Domain d4bc1c_: 4bc1 C: [192619]
    automated match to d1maac_
    complexed with cl, nag, so4, tqv
  4. Domain d4bc1d_: 4bc1 D: [192857]
    automated match to d1maac_
    complexed with cl, nag, so4, tqv
17. Domains for 4btl:
  1. Domain d4btla_: 4btl A: [227837]
    automated match to d1n5ra_
    complexed with 5gz, edo, nag, pe3
  2. Domain d4btlb_: 4btl B: [227836]
    automated match to d1n5rb_
    complexed with 5gz, edo, nag, pe3
Pacific electric ray (Torpedo californica) [TaxId:7787] [53477] (76 PDB entries)
Uniprot P04058 25-556
1. Domain for 1acj:
  - Domain d1acja_: 1acj A: [34588]
    complexed with tha
2. Domain for 1acl:
  - Domain d1acla_: 1acl A: [34590]
    complexed with dme
3. Domain for 1amn:
  - Domain d1amna_: 1amn A: [34587]
    complexed with naf, so4
4. Domain for 1ax9:
  - Domain d1ax9a_: 1ax9 A: [34589]
    complexed with edr
5. Domain for 1cfj:
  - Domain d1cfja_: 1cfj A: [34586]
    complexed with gb, nag, ndg
6. Domain for 1dx6:
  - Domain d1dx6a_: 1dx6 A: [34602]
    complexed with gnt, nag, pg4
7. Domain for 1e3q:
  - Domain d1e3qa_: 1e3q A: [34607]
    complexed with ebw, nag, so4
8. Domain for 1e66:
  - Domain d1e66a_: 1e66 A: [59291]
    complexed with hux, nag
9. Domain for 1ea5:
  - Domain d1ea5a_: 1ea5 A: [34592]
    complexed with nag
10. Domain for 1eve:
  - Domain d1evea_: 1eve A: [34585]
    complexed with e20, nag
11. Domain for 1fss:
  - Domain d1fssa_: 1fss A: [34608]
    Other proteins in same PDB: d1fssb_
    complexed with nag, zn
12. Domain for 1gpk:
  - Domain d1gpka_: 1gpk A: [76260]
    complexed with hup, nag
13. Domain for 1gpn:
  - Domain d1gpna_: 1gpn A: [76261]
    complexed with hub, nag
14. Domain for 1gqr:
  - Domain d1gqra_: 1gqr A: [70374]
    complexed with emm, nag, saf
15. Domain for 1gqs:
  - Domain d1gqsa_: 1gqs A: [70375]
    complexed with nag, saf
16. Domain for 1h22:
  - Domain d1h22a_: 1h22 A: [76514]
    complexed with e10, nag
17. Domain for 1h23:
  - Domain d1h23a_: 1h23 A: [76515]
    complexed with e12, nag
18. Domain for 1hbj:
  - Domain d1hbja_: 1hbj A: [65785]
    complexed with fbq, mes, nag, pg4
19. Domain for 1jjb:
  - Domain d1jjba_: 1jjb A: [71695]
    complexed with nag, pe7
20. Domain for 1oce:
  - Domain d1ocea_: 1oce A: [34591]
    complexed with mf2
21. Domain for 1odc:
  - Domain d1odca_: 1odc A: [118700]
    automated match to d1eve__
    complexed with a8b, nag
22. Domain for 1qid:
  - Domain d1qida_: 1qid A: [34593]
23. Domain for 1qie:
  - Domain d1qiea_: 1qie A: [34594]
24. Domain for 1qif:
  - Domain d1qifa_: 1qif A: [34596]
25. Domain for 1qig:
  - Domain d1qiga_: 1qig A: [34598]
26. Domain for 1qih:
  - Domain d1qiha_: 1qih A: [34600]
27. Domain for 1qii:
  - Domain d1qiia_: 1qii A: [34603]
28. Domain for 1qij:
  - Domain d1qija_: 1qij A: [34604]
29. Domain for 1qik:
  - Domain d1qika_: 1qik A: [34606]
30. Domain for 1qim:
  - Domain d1qima_: 1qim A: [34605]
31. Domain for 1qti:
  - Domain d1qtia_: 1qti A: [34601]
    complexed with gnt
32. Domain for 1som:
  - Domain d1soma_: 1som A: [34584]
    complexed with nag, unx, vxa
33. Domain for 1u65:
  - Domain d1u65a_: 1u65 A: [119563]
    automated match to d1eve__
    complexed with cp0, iod, nag
34. Domain for 1vot:
  - Domain d1vota_: 1vot A: [34583]
    complexed with hup
35. Domain for 1vxo:
  - Domain d1vxoa_: 1vxo A: [34599]
    complexed with nag, ndg, vxa
36. Domain for 1vxr:
  - Domain d1vxra_: 1vxr A: [34595]
    complexed with mes, ndg, vx
37. Domain for 1w4l:
  - Domain d1w4la_: 1w4l A: [114192]
    complexed with gl8, nag
38. Domain for 1w6r:
  - Domain d1w6ra_: 1w6r A: [114283]
    complexed with gnt, mg, nag
39. Domains for 1w75:
  1. Domain d1w75a_: 1w75 A: [114313]
    complexed with nag
  2. Domain d1w75b_: 1w75 B: [114314]
    complexed with nag
40. Domains for 1w76:
  1. Domain d1w76a_: 1w76 A: [114315]
    complexed with gnt, nag
  2. Domain d1w76b_: 1w76 B: [114316]
    complexed with gnt, nag
41. Domain for 1zgb:
  - Domain d1zgba_: 1zgb A: [125023]
    automated match to d1eve__
    complexed with a1e, nag
42. Domains for 1zgc:
  1. Domain d1zgca_: 1zgc A: [125024]
    automated match to d1eve__
    complexed with a2e, nag
  2. Domain d1zgcb_: 1zgc B: [125025]
    automated match to d1eve__
    complexed with a2e, nag
43. Domain for 2ace:
  - Domain d2acea_: 2ace A: [34582]
    complexed with ach
44. Domain for 2ack:
  - Domain d2acka_: 2ack A: [34581]
    complexed with edr
45. Domain for 2bag:
  - Domain d2baga_: 2bag A: [128236]
    automated match to d1eve__
    complexed with 1pe, gsg, mes, nag
46. Domain for 2c4h:
  - Domain d2c4ha_: 2c4h A: [129815]
    automated match to d1eve__
    complexed with ace, act, at3, cl, nag, ndg, pge
47. Domain for 2c58:
  - Domain d2c58a_: 2c58 A: [129891]
    automated match to d1eve__
    complexed with at3, cl, etm, nag, pge
48. Domain for 2c5f:
  - Domain d2c5fa_: 2c5f A: [129914]
    automated match to d1eve__
    complexed with chh, nag, ndg, nwa, pge
49. Domain for 2c5g:
  - Domain d2c5ga_: 2c5g A: [129915]
    automated match to d1eve__
    complexed with cl, etm, nag, pge
50. Domain for 2cek:
  - Domain d2ceka_: 2cek A: [130347]
    automated match to d1eve__
    complexed with mes, n8t, nag, ndg, pge
51. Domain for 2ckm:
  - Domain d2ckma_: 2ckm A: [130567]
    automated match to d1eve__
    complexed with aa7, nag
52. Domain for 2cmf:
  - Domain d2cmfa_: 2cmf A: [130629]
    automated match to d1eve__
    complexed with f11, nag
53. Domain for 2dfp:
  - Domain d2dfpa_: 2dfp A: [34597]
    complexed with mes, nag
54. Domain for 2j3d:
  - Domain d2j3da1: 2j3d A:4-535 [147858]
    automatically matched to d1evea_
    complexed with mg, nag
55. Domain for 2j3q:
  - Domain d2j3qa_: 2j3q A: [147859]
    automated match to d1evea_
    complexed with mg, nag, ndg, tfl
56. Domain for 2j4f:
  - Domain d2j4fa_: 2j4f A: [138002]
    automated match to d1eve__
    complexed with hg
57. Domains for 2v96:
  1. Domain d2v96a_: 2v96 A: [152797]
    automated match to d1evea_
    complexed with cfq, nag
  2. Domain d2v96b_: 2v96 B: [152798]
    automated match to d1evea_
    complexed with cfq, nag
58. Domains for 2v97:
  1. Domain d2v97a_: 2v97 A: [152799]
    automated match to d1evea_
    complexed with cfq, cl, nag
  2. Domain d2v97b_: 2v97 B: [152800]
    automated match to d1evea_
    complexed with cfq, cl, nag
59. Domains for 2v98:
  1. Domain d2v98a1: 2v98 A:4-535 [152801]
    automatically matched to d1evea_
    complexed with cfq, cl, nag
  2. Domain d2v98b1: 2v98 B:4-535 [152802]
    automatically matched to d1evea_
    complexed with cfq, cl, nag
60. Domains for 2va9:
  1. Domain d2va9a_: 2va9 A: [152824]
    automated match to d1evea_
    complexed with nag
  2. Domain d2va9b_: 2va9 B: [152825]
    automated match to d1evea_
    complexed with nag
61. Domains for 2vja:
  1. Domain d2vjaa_: 2vja A: [153186]
    automated match to d1evea_
    complexed with ccd, cl, nag, pge
  2. Domain d2vjab_: 2vja B: [153187]
    automated match to d1evea_
    complexed with ccd, cl, nag, pge
62. Domains for 2vjb:
  1. Domain d2vjba_: 2vjb A: [153188]
    automated match to d1evea_
    complexed with ccd, cl, nag, pge
  2. Domain d2vjbb_: 2vjb B: [153189]
    automated match to d1evea_
    complexed with ccd, cl, nag, pge
63. Domains for 2vjc:
  1. Domain d2vjca_: 2vjc A: [153190]
    automated match to d1evea_
    complexed with ccd, chh, cl, nag, pge
  2. Domain d2vjcb_: 2vjc B: [153191]
    automated match to d1evea_
    complexed with ccd, chh, cl, nag, pge
64. Domains for 2vjd:
  1. Domain d2vjda_: 2vjd A: [153192]
    automated match to d1evea_
    complexed with ccd, cl, nag, pge
  2. Domain d2vjdb_: 2vjd B: [153193]
    automated match to d1evea_
    complexed with ccd, cl, nag, pge
65. Domain for 2vq6:
  - Domain d2vq6a_: 2vq6 A: [153425]
    automated match to d1evea_
    complexed with fp1, nag, so4
66. Domains for 2vt6:
  1. Domain d2vt6a_: 2vt6 A: [153538]
    automated match to d1evea_
    complexed with cl, nag, pge
  2. Domain d2vt6b_: 2vt6 B: [153539]
    automated match to d1evea_
    complexed with cl, nag, pge
67. Domains for 2vt7:
  1. Domain d2vt7a_: 2vt7 A: [153540]
    automated match to d1evea_
    complexed with cl, nag, pge
  2. Domain d2vt7b_: 2vt7 B: [153541]
    automated match to d1evea_
    complexed with cl, nag, pge
68. Domain for 2wfz:
  - Domain d2wfza_: 2wfz A: [169320]
    automated match to d1evea_
    complexed with cl, gd8, peg, pg4, trs
69. Domain for 2wg0:
  - Domain d2wg0a_: 2wg0 A: [169321]
    automated match to d1evea_
    complexed with cl, gb, mes, nag, peg, pg4, pge
70. Domain for 2wg1:
  - Domain d2wg1a_: 2wg1 A: [169322]
    automated match to d1evea_
    complexed with fp1, gb, mes, nag, peg, pg4, pge
71. Domain for 2wg2:
  - Domain d2wg2a_: 2wg2 A: [169323]
    automated match to d1evea_
    complexed with cl, gd8, peg, pg4, trs
72. Domains for 2xi4:
  1. Domain d2xi4a_: 2xi4 A: [170108]
    automated match to d1evea_
    complexed with aft, cl, k, nag, peg, pge
  2. Domain d2xi4b_: 2xi4 B: [170109]
    automated match to d1evea_
    complexed with aft, cl, k, nag, peg, pge
73. Domain for 3gel:
  - Domain d3gela_: 3gel A: [176580]
    automated match to d1acja_
74. Domain for 3i6m:
  - Domain d3i6ma_: 3i6m A: [178117]
    automated match to d1evea_
    complexed with g3x, nag
75. Domain for 3i6z:
  - Domain d3i6za_: 3i6z A: [178121]
    automated match to d1evea_
    complexed with g6x, nag
76. Domain for 3m3d:
  - Domain d3m3da_: 3m3d A: [180786]
    automated match to d1evea_
    complexed with nag, peg, pg4, xe

More info for Protein Acetylcholinesterase from c.69.1.1: Acetylcholinesterase-like

Timeline for Protein Acetylcholinesterase from c.69.1.1: Acetylcholinesterase-like:

Protein Acetylcholinesterase from c.69.1.1: Acetylcholinesterase-like first appeared (with stable ids) in SCOP 1.55
Protein Acetylcholinesterase from c.69.1.1: Acetylcholinesterase-like appears in SCOPe 2.02
Protein Acetylcholinesterase from c.69.1.1: Acetylcholinesterase-like appears in SCOPe 2.04
Protein Acetylcholinesterase from c.69.1.1: Acetylcholinesterase-like appears in the current release, SCOPe 2.08