SCOPe 2.03: Domain d4bc1d_: 4bc1 D:

Lineage for d4bc1d_ (4bc1 D:)

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (42 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.1: Acetylcholinesterase-like [53475] (6 proteins)
   automatically mapped to Pfam PF00135

6. Protein Acetylcholinesterase [53476] (5 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [53479] (17 PDB entries)

8. Domain d4bc1d_: 4bc1 D: [192857]
   automated match to d1maac_
   complexed with cl, nag, so4, tqv

Details for d4bc1d_

PDB Entry: 4bc1, 2.95 Å

PDB Description: structure of mouse acetylcholinesterase inhibited by cbdp (30-min soak): cresyl-saligenin-phosphoserine adduct

PDB Compounds: (D:) acetylcholinesterase

SCOPe Domain Sequences for d4bc1d_:

Sequence; same for both SEQRES and ATOM records:

>d4bc1d_ c.69.1.1 (D:) Acetylcholinesterase {Mouse (Mus musculus) [TaxId: 10090]}
edpqllvrvrggqlrgirlkapggpvsaflgipfaeppvgsrrfmppepkrpwsgvldat
tfqnvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprpasptpvliwiygggf
ysgaasldvydgrflaqvegavlvsmnyrvgtfgflalpgsreapgnvglldqrlalqwv
qeniaafggdpmsvtlfgesagaasvgmhilslpsrslfhravlqsgtpngpwatvsage
arrratllarlvgcppggaggndteliaclrtrpaqdlvdhewhvlpqesifrfsfvpvv
dgdflsdtpealintgdfqdlqvlvgvvkdegsyflvygvpgfskdneslisraqflagv
rigvpqasdlaaeavvlhytdwlhpedpthlrdamsavvgdhnvvcpvaqlagrlaaqga
rvyayifehrastltwplwmgvphgyeiefifglpldpslnytteerifaqrlmkywtnf
artgdpndprdskspqwppyttaaqqyvslnlkplevrrglraqtcafwnrflpkllsat

Timeline for d4bc1d_:

• d4bc1d_ first appeared in SCOPe 2.02
  
• d4bc1d_ appears in SCOPe 2.04
  
• d4bc1d_ appears in the current release, SCOPe 2.08