Lineage for Family c.37.1.10: Nitrogenase iron protein-like

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2109203Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. 2109204Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families) (S)
    division into families based on beta-sheet topologies
  5. 2111791Family c.37.1.10: Nitrogenase iron protein-like [52652] (16 protein domains)
    core: parallel beta-sheet of 7 strands; order 3241567

Protein Domains:

  1. 2111792Adenylosuccinate synthetase, PurA [52655] (5 species)
    common fold is interrupted by an all-alpha subdomain, residues 100-200
    1. 2111793Species Escherichia coli [TaxId:562] [52656] (23 PDB entries)
    2. 2111822Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [102372] (1 PDB entry)
    3. 2111824Species Mouse (Mus musculus) [TaxId:10090] [69491] (9 PDB entries)
    4. 2111836Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [52657] (1 PDB entry)
    5. 2111839Species Wheat (Triticum aestivum) [TaxId:4565] [52658] (1 PDB entry)
  2. 2111842Arsenite-translocating ATPase ArsA [52668] (1 species)
    Duplication: consists of two domains of this fold arranged as the NIP subunits in the dimer
  3. 2111856ATP(GTP)-binding protein PAB0955 [142297] (1 species)
    PYRAB14380; belongs to Pfam PF03029
  4. 2111867Cell division regulator MinD [64019] (3 species)
    1. 2111868Species Archaeoglobus fulgidus [TaxId:2234] [64020] (1 PDB entry)
    2. 2111870Species Pyrococcus furiosus [TaxId:2261] [64021] (2 PDB entries)
    3. 2111873Species Pyrococcus horikoshii [TaxId:53953] [64022] (1 PDB entry)
  5. 2111875CTP synthase PyrG, N-terminal domain [110551] (3 species)
    1. 2111876Species Escherichia coli [TaxId:562] [110552] (1 PDB entry)
      Uniprot P08398
    2. 2111879Species Human (Homo sapiens) [TaxId:9606] [159561] (1 PDB entry)
      Uniprot Q5VW67 1-273
    3. 2111882Species Thermus thermophilus [TaxId:274] [110553] (3 PDB entries)
      Uniprot Q5SIA8
  6. 2111886Dethiobiotin synthetase [52653] (1 species)
  7. 2111901Formyltetrahydrofolate synthetase [52659] (1 species)
    modified P-loop; there are many insertions in the common fold
  8. 2111919GTPase domain of the signal recognition particle receptor FtsY [52666] (3 species)
    1. 2111920Species Escherichia coli [TaxId:562] [52667] (2 PDB entries)
    2. 2111923Species Thermotoga maritima [TaxId:2336] [110550] (1 PDB entry)
      Uniprot Q9WZ40
    3. 2111926Species Thermus aquaticus [TaxId:271] [102374] (3 PDB entries)
  9. 2111930GTPase domain of the signal sequence recognition protein Ffh [52664] (3 species)
    1. 2111931Species Acidianus ambivalens [TaxId:2283] [64023] (2 PDB entries)
    2. 2111934Species Sulfolobus solfataricus [TaxId:2287] [102373] (2 PDB entries)
    3. 2111941Species Thermus aquaticus [TaxId:271] [52665] (17 PDB entries)
  10. 2111970Hypothetical protein TM0796 [142299] (1 species)
    member of Pfam PF07755; DUF1611; contains extra N-terminal alpha/beta fold of Rossmann-fold topology, parallel beta-sheet, strand order 312456
  11. 2111974Hypothetical protein YjiA, N-terminal domain [89671] (1 species)
    homologue of the cobalamin biosynthesis protein CobW
  12. 2111981LAO/AO transport system kinase ArgK [159562] (1 species)
    member of Pfam PF03308; contains extra N-terminal 3-helical bundle and extra C-terminal helical dimerisation domain
  13. 2111984Metallochaperone MeaB [159564] (1 species)
    ArgK-like (sub)family; Pfam PF03308
  14. 2111998Molybdopterin-guanine dinucleotide biosynthesis protein MobB [89673] (2 species)
    forms segment-swapped dimer
    1. 2111999Species Bacillus stearothermophilus [TaxId:1422] [117539] (1 PDB entry)
      Uniprot Q5L1X2 # 91% sequence identity
    2. 2112001Species Escherichia coli [TaxId:562] [89674] (2 PDB entries)
  15. 2112006Nitrogenase iron protein [52661] (2 species)
    1. 2112007Species Azotobacter vinelandii [TaxId:354] [52662] (21 PDB entries)
    2. 2112080Species Clostridium pasteurianum [TaxId:1501] [52663] (1 PDB entry)
  16. 2112083automated matches [190304] (11 species)
    not a true protein
    1. 2112084Species Azotobacter vinelandii [TaxId:354] [269127] (1 PDB entry)
    2. 2112089Species Escherichia coli K-12 [TaxId:83333] [229053] (2 PDB entries)
    3. 2112093Species Escherichia coli [TaxId:562] [187113] (1 PDB entry)
    4. 2112095Species Human (Homo sapiens) [TaxId:9606] [189076] (3 PDB entries)
    5. 2112103Species Moorella thermoacetica [TaxId:1525] [189834] (6 PDB entries)
    6. 2112115Species Moorella thermoacetica [TaxId:264732] [196795] (3 PDB entries)
    7. 2112121Species Thermus aquaticus [TaxId:271] [255076] (4 PDB entries)
    8. 2112129Species Yersinia pestis [TaxId:214092] [188914] (1 PDB entry)
    9. 2274984Species Sulfolobus solfataricus [TaxId:273057] [318285] (1 PDB entry)
    10. 2274997Species Sulfolobus solfataricus [TaxId:2287] [318298] (1 PDB entry)
    11. 2275940Species Tepidanaerobacter acetatoxydans [TaxId:1209989] [319241] (2 PDB entries)

More info for Family c.37.1.10: Nitrogenase iron protein-like

Timeline for Family c.37.1.10: Nitrogenase iron protein-like: