SCOP 1.73: Protein: Glutathione reductase

Lineage for Protein: Glutathione reductase

Root: SCOP 1.73
Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
Fold c.3: FAD/NAD(P)-binding domain [51904] (1 superfamily)
core: 3 layers, b/b/a; central parallel beta-sheet of 5 strands, order 32145; top antiparallel beta-sheet of 3 strands, meander
Superfamily c.3.1: FAD/NAD(P)-binding domain [51905] (7 families)

Family c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains [51943] (15 proteins)
duplication: both domains have similar folds and functions
most members of the family contain common C-terminal alpha+beta domain

Protein Glutathione reductase [51944] (3 species)

Species:

Escherichia coli [TaxId:562] [51946] (4 PDB entries)
1. Domains for 1ger:
  1. Domain d1gera1: 1ger A:3-146,A:263-335 [30477]
    Other proteins in same PDB: d1gera3, d1gerb3
  2. Domain d1gera2: 1ger A:147-262 [30478]
    Other proteins in same PDB: d1gera3, d1gerb3
  3. Domain d1gerb1: 1ger B:2-146,B:263-335 [30479]
    Other proteins in same PDB: d1gera3, d1gerb3
  4. Domain d1gerb2: 1ger B:147-262 [30480]
    Other proteins in same PDB: d1gera3, d1gerb3
    complexed with fad
2. Domains for 1ges:
  1. Domain d1gesa1: 1ges A:3-146,A:263-335 [30473]
    Other proteins in same PDB: d1gesa3, d1gesb3
  2. Domain d1gesa2: 1ges A:147-262 [30474]
    Other proteins in same PDB: d1gesa3, d1gesb3
  3. Domain d1gesb1: 1ges B:2-146,B:263-335 [30475]
    Other proteins in same PDB: d1gesa3, d1gesb3
  4. Domain d1gesb2: 1ges B:147-262 [30476]
    Other proteins in same PDB: d1gesa3, d1gesb3
    complexed with fad; mutant
3. Domains for 1get:
  1. Domain d1geta1: 1get A:3-146,A:263-335 [30481]
    Other proteins in same PDB: d1geta3, d1getb3
  2. Domain d1geta2: 1get A:147-262 [30482]
    Other proteins in same PDB: d1geta3, d1getb3
  3. Domain d1getb1: 1get B:2-146,B:263-335 [30483]
    Other proteins in same PDB: d1geta3, d1getb3
  4. Domain d1getb2: 1get B:147-262 [30484]
    Other proteins in same PDB: d1geta3, d1getb3
    complexed with fad, nap
4. Domains for 1geu:
  1. Domain d1geua1: 1geu A:3-146,A:263-335 [30485]
    Other proteins in same PDB: d1geua3, d1geub3
  2. Domain d1geua2: 1geu A:147-262 [30486]
    Other proteins in same PDB: d1geua3, d1geub3
  3. Domain d1geub1: 1geu B:2-146,B:263-335 [30487]
    Other proteins in same PDB: d1geua3, d1geub3
  4. Domain d1geub2: 1geu B:147-262 [30488]
    Other proteins in same PDB: d1geua3, d1geub3
    complexed with fad, nad; mutant
Human (Homo sapiens) [TaxId:9606] [51945] (17 PDB entries)
1. Domains for 1bwc:
  1. Domain d1bwca1: 1bwc A:18-165,A:291-363 [30459]
    Other proteins in same PDB: d1bwca3
  2. Domain d1bwca2: 1bwc A:166-290 [30460]
    Other proteins in same PDB: d1bwca3
    complexed with aj3, cl, fad
2. Domains for 1dnc:
  1. Domain d1dnca1: 1dnc A:18-165,A:291-363 [30443]
    Other proteins in same PDB: d1dnca3
  2. Domain d1dnca2: 1dnc A:166-290 [30444]
    Other proteins in same PDB: d1dnca3
    complexed with fad, gtt, po4
3. Domains for 1gra:
  1. Domain d1graa1: 1gra A:18-165,A:291-363 [30451]
    Other proteins in same PDB: d1graa3
  2. Domain d1graa2: 1gra A:166-290 [30452]
    Other proteins in same PDB: d1graa3
    complexed with fad, gsh, ndp
4. Domains for 1grb:
  1. Domain d1grba1: 1grb A:18-165,A:291-363 [30447]
    Other proteins in same PDB: d1grba3
  2. Domain d1grba2: 1grb A:166-290 [30448]
    Other proteins in same PDB: d1grba3
    complexed with fad, nad, ndp, po4
5. Domains for 1gre:
  1. Domain d1grea1: 1gre A:18-165,A:291-363 [30453]
    Other proteins in same PDB: d1grea3
  2. Domain d1grea2: 1gre A:166-290 [30454]
    Other proteins in same PDB: d1grea3
    complexed with fad, gsh, po4
6. Domains for 1grf:
  1. Domain d1grfa1: 1grf A:18-165,A:291-363 [30457]
    Other proteins in same PDB: d1grfa3
  2. Domain d1grfa2: 1grf A:166-290 [30458]
    Other proteins in same PDB: d1grfa3
    complexed with cnm, fad, po4
7. Domains for 1grg:
  1. Domain d1grga1: 1grg A:18-165,A:291-363 [30455]
    Other proteins in same PDB: d1grga3
  2. Domain d1grga2: 1grg A:166-290 [30456]
    Other proteins in same PDB: d1grga3
    complexed with cec, fad, po4
8. Domains for 1grt:
  1. Domain d1grta1: 1grt A:17-165,A:291-363 [30467]
    Other proteins in same PDB: d1grta3
  2. Domain d1grta2: 1grt A:166-290 [30468]
    Other proteins in same PDB: d1grta3
    complexed with fad; mutant
9. Domains for 1gsn:
  1. Domain d1gsna1: 1gsn A:18-165,A:291-363 [30445]
    Other proteins in same PDB: d1gsna3
  2. Domain d1gsna2: 1gsn A:166-290 [30446]
    Other proteins in same PDB: d1gsna3
    complexed with fad, gtt, po4
10. Domains for 1k4q:
  1. Domain d1k4qa1: 1k4q A:18-165,A:291-363 [68140]
    Other proteins in same PDB: d1k4qa3
  2. Domain d1k4qa2: 1k4q A:166-290 [68141]
    Other proteins in same PDB: d1k4qa3
    complexed with fad, niy
11. Domains for 1xan:
  1. Domain d1xana1: 1xan A:18-165,A:291-363 [30449]
    Other proteins in same PDB: d1xana3
  2. Domain d1xana2: 1xan A:166-290 [30450]
    Other proteins in same PDB: d1xana3
    complexed with fad, hxp
12. Domains for 2grt:
  1. Domain d2grta1: 2grt A:18-165,A:291-363 [30469]
    Other proteins in same PDB: d2grta3
  2. Domain d2grta2: 2grt A:166-290 [30470]
    Other proteins in same PDB: d2grta3
    complexed with fad, gds; mutant
13. Domains for 3grs:
  1. Domain d3grsa1: 3grs A:18-165,A:291-363 [30441]
    Other proteins in same PDB: d3grsa3
  2. Domain d3grsa2: 3grs A:166-290 [30442]
    Other proteins in same PDB: d3grsa3
    complexed with fad
14. Domains for 3grt:
  1. Domain d3grta1: 3grt A:18-165,A:291-363 [30463]
    Other proteins in same PDB: d3grta3
  2. Domain d3grta2: 3grt A:166-290 [30464]
    Other proteins in same PDB: d3grta3
    complexed with fad, ts2; mutant
15. Domains for 4gr1:
  1. Domain d4gr1a1: 4gr1 A:18-165,A:291-363 [30461]
    Other proteins in same PDB: d4gr1a3
  2. Domain d4gr1a2: 4gr1 A:166-290 [30462]
    Other proteins in same PDB: d4gr1a3
    complexed with fad, po4, rgs
16. Domains for 4grt:
  1. Domain d4grta1: 4grt A:18-165,A:291-363 [30471]
    Other proteins in same PDB: d4grta3
  2. Domain d4grta2: 4grt A:166-290 [30472]
    Other proteins in same PDB: d4grta3
    complexed with fad, ts3; mutant
17. Domains for 5grt:
  1. Domain d5grta1: 5grt A:18-165,A:291-363 [30465]
    Other proteins in same PDB: d5grta3
  2. Domain d5grta2: 5grt A:166-290 [30466]
    Other proteins in same PDB: d5grta3
    complexed with fad, ts4; mutant
Plasmodium falciparum [TaxId:5833] [89548] (1 PDB entry)
- Domains for 1onf:
  1. Domain d1onfa1: 1onf A:1-153,A:271-376 [87141]
    Other proteins in same PDB: d1onfa3
  2. Domain d1onfa2: 1onf A:154-270 [87142]
    Other proteins in same PDB: d1onfa3
    complexed with fad

More info for Protein Glutathione reductase from c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains

Timeline for Protein Glutathione reductase from c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains:

Protein Glutathione reductase from c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains first appeared (with stable ids) in SCOP 1.55
Protein Glutathione reductase from c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains appears in SCOP 1.71
Protein Glutathione reductase from c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains appears in SCOP 1.75
Protein Glutathione reductase from c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains last appears in SCOPe 2.07