Lineage for Family a.4.5.5: ArsR-like transcriptional regulators

  1. Root: SCOPe 2.08
  2. Class a: All alpha proteins [46456] (290 folds)
  3. Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (14 superfamilies)
    core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down
  4. Superfamily a.4.5: 'Winged helix' DNA-binding domain [46785] (86 families) (S)
    contains a small beta-sheet (wing)
  5. Family a.4.5.5: ArsR-like transcriptional regulators [46801] (5 proteins)
    The N- and C-terminal helical extensions to the common fold form the dimer interface

Proteins:

  1. Cadmium efflux system accessory protein CadC [140239] (1 species)
  2. Metal-sensing transcriptional repressor CzrA [109664] (1 species)
  3. Putative arsenical resistance operon repressor AF0168 [116786] (1 species)
    lacks the extra C-terminal helix
  4. SmtB repressor [46802] (1 species)
  5. automated matches [191027] (2 species)
    not a true protein
    1. Species Staphylococcus aureus [TaxId:1280] [188833] (5 PDB entries)
    2. Species Staphylococcus aureus [TaxId:158879] [193060] (1 PDB entry)

More info for Family a.4.5.5: ArsR-like transcriptional regulators

Timeline for Family a.4.5.5: ArsR-like transcriptional regulators: