SCOP 1.63: Domain d1aq1__: 1aq1 -

Lineage for d1aq1__ (1aq1 -)

1. Root: SCOP 1.63

2. Class d: Alpha and beta proteins (a+b) [53931] (224 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (6 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.1: Serine/threonin kinases [56113] (21 proteins)

6. Protein Cyclin-dependent PK (CDK, different isozymes) [56114] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56115] (47 PDB entries)

8. Domain d1aq1__: 1aq1 - [41599]
   complexed with stu

Details for d1aq1__

PDB Entry: 1aq1, 2 Å

PDB Description: human cyclin dependent kinase 2 complexed with the inhibitor staurosporine

SCOP Domain Sequences for d1aq1__:

Sequence, based on SEQRES records:

>d1aq1__ d.144.1.1 (-) Cyclin-dependent PK (CDK, different isozymes) {Human (Homo sapiens)}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

Sequence, based on observed residues (ATOM records):

>d1aq1__ d.144.1.1 (-) Cyclin-dependent PK (CDK, different isozymes) {Human (Homo sapiens)}
menfqkvekigegtygvvykarnkltgevvalkkivpstaireisllkelnhpnivklld
vihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdl
kpqnllintegaikladfglevvtlwyrapeillgckyystavdiwslgcifaemvtrra
lfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedgrs
llsqmlhydpnkrisakaalahpffqdvtkpvphlrl

Timeline for d1aq1__:

• d1aq1__ first appeared (with stable ids) in SCOP 1.55
  
• d1aq1__ appears in SCOP 1.61
  
• d1aq1__ appears in SCOP 1.65
  
• d1aq1__ appears in the current release, SCOPe 2.08, called d1aq1a_