SCOP 1.63: Domain d2tsrd_: 2tsr D:

Lineage for d2tsrd_ (2tsr D:)

1. Root: SCOP 1.63

2. Class d: Alpha and beta proteins (a+b) [53931] (224 folds)

3. Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (1 family)

5. Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (3 proteins)

6. Protein Thymidylate synthase [55833] (7 species)

7. Species Rat (Rattus norvegicus) [TaxId:10116] [55839] (2 PDB entries)

8. Domain d2tsrd_: 2tsr D: [41046]
   complexed with d16, ump

Details for d2tsrd_

PDB Entry: 2tsr, 2.6 Å

PDB Description: thymidylate synthase from rat in ternary complex with dump and tomudex

SCOP Domain Sequences for d2tsrd_:

Sequence; same for both SEQRES and ATOM records:

>d2tsrd_ d.117.1.1 (D:) Thymidylate synthase {Rat (Rattus norvegicus)}
qhgelqylrqvehimrcgfkkedrtgtgtlsvfgmqaryslrdefpllttkrvfwkgvle
ellwfikgstnakelsskgvriwdangsrdfldslgfsarqegdlgpvygfqwrhfgady
kdmdsdysgqgvdqlqkvidtiktnpddrriimcawnpkdlplmalppchalcqfyvvng
elscqlyqrsgdmglgvpfniasyalltymiahitglqpgdfvhtlgdahiylnhieplk
iqlqreprpfpklrilrkvetiddfkvedfqiegynphpti

Timeline for d2tsrd_:

• d2tsrd_ first appeared (with stable ids) in SCOP 1.55
  
• d2tsrd_ appears in SCOP 1.61
  
• d2tsrd_ appears in SCOP 1.65
  
• d2tsrd_ appears in the current release, SCOPe 2.08