SCOPe 2.08: Domain d6v9lc1: 6v9l C:1-166

Lineage for d6v9lc1 (6v9l C:1-166)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (81 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein cH-p21 Ras protein [52593] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52594] (160 PDB entries)
   Uniprot Q6P716

8. Domain d6v9lc1: 6v9l C:1-166 [392613]
   Other proteins in same PDB: d6v9lb1, d6v9lb2, d6v9lc2
   automated match to d6q21a_
   complexed with act, fmt, gnp, gol, mg, na, qtj

Details for d6v9lc1

PDB Entry: 6v9l, 1.7 Å

PDB Description: expanding the chemical landscape of sos1 activators using fragment based methods

PDB Compounds: (C:) gtpase hras

SCOPe Domain Sequences for d6v9lc1:

Sequence; same for both SEQRES and ATOM records:

>d6v9lc1 c.37.1.8 (C:1-166) cH-p21 Ras protein {Human (Homo sapiens) [TaxId: 9606]}
mteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildtag
qeeysamrdqymrtgegflcvfainntksfedihqyreqikrvkdsddvpmvlvgnkcdl
aartvesrqaqdlarsygipyietsaktrqgvedafytlvreirqh

Timeline for d6v9lc1:

• d6v9lc1 first appeared in SCOPe 2.07