SCOPe 2.07: Domain d6o4wa_: 6o4w A:

Lineage for d6o4wa_ (6o4w A:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (42 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.1: Acetylcholinesterase-like [53475] (6 proteins)
   automatically mapped to Pfam PF00135

6. Protein Acetylcholinesterase [53476] (6 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [53479] (43 PDB entries)

8. Domain d6o4wa_: 6o4w A: [370983]
   automated match to d1maac_
   complexed with e20, gol, no3

Details for d6o4wa_

PDB Entry: 6o4w, 2.35 Å

PDB Description: binary complex of native hache with donepezil

PDB Compounds: (A:) acetylcholinesterase

SCOPe Domain Sequences for d6o4wa_:

Sequence; same for both SEQRES and ATOM records:

>d6o4wa_ c.69.1.1 (A:) Acetylcholinesterase {Mouse (Mus musculus) [TaxId: 10090]}
edaellvtvrggrlrgirlktpggpvsaflgipfaeppmgprrflppepkqpwsgvvdat
tfqsvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprptsptpvlvwiygggf
ysgassldvydgrflvqaertvlvsmnyrvgafgflalpgsreapgnvglldqrlalqwv
qenvaafggdptsvtlfgesagaasvgmhllsppsrglfhravlqsgapngpwatvgmge
arrratqlahlvgcppggtggndtelvaclrtrpaqvlvnhewhvlpqesvfrfsfvpvv
dgdflsdtpealinagdfhglqvlvgvvkdegsyflvygapgfskdneslisraeflagv
rvgvpqvsdlaaeavvlhytdwlhpedparlrealsdvvgdhnvvcpvaqlagrlaaqga
rvyayvfehrastlswplwmgvphgyeiefifgipldpsrnytaeekifaqrlmrywanf
artgdpneprdpkapqwppytagaqqyvsldlrplevrrglraqacafwnrflpkllsat

Timeline for d6o4wa_:

• d6o4wa_ is new in SCOPe 2.07-stable
  
• d6o4wa_ appears in the current release, SCOPe 2.08