SCOPe 2.08: Domain d6dgsb1: 6dgs B:1-313

Lineage for d6dgsb1 (6dgs B:1-313)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.4: FMN-linked oxidoreductases [51395] (2 families)

5. Family c.1.4.1: FMN-linked oxidoreductases [51396] (19 proteins)

6. Protein automated matches [190228] (20 species)
   not a true protein

7. Species Leishmania major [TaxId:5664] [255853] (9 PDB entries)

8. Domain d6dgsb1: 6dgs B:1-313 [369453]
   Other proteins in same PDB: d6dgsa2, d6dgsb2
   automated match to d2djxa_
   complexed with fmn, gol, so4; mutant

Details for d6dgsb1

PDB Entry: 6dgs, 1.75 Å

PDB Description: crystal structure of leishmania major dihydroorotate dehydrogenase mutant y142a

PDB Compounds: (B:) Dihydroorotate dehydrogenase (fumarate)

SCOPe Domain Sequences for d6dgsb1:

Sequence, based on SEQRES records:

>d6dgsb1 c.1.4.1 (B:1-313) automated matches {Leishmania major [TaxId: 5664]}
mslqvnllnntfanpfmnaagvmcttteelvamtesasgslvsksctpalregnptpryq
alplgsinsmglpnngfdfylayaaeqhdygkkplflsmsglsmrenvemckrlaavate
kgvilelnlscpnvpgkpqvaadfdamrqcltavsevyphsfgvkmppyfdfahfdaaae
ilnefpkvqfitcinsignglvidaetesvvikpkqgfgglggryvlptalaninafyrr
cpgklifgcggvytgedaflhvlagasmvqvgtalqeegpsiferltsellgvmakkryq
tldefrgkvrtld

Sequence, based on observed residues (ATOM records):

>d6dgsb1 c.1.4.1 (B:1-313) automated matches {Leishmania major [TaxId: 5664]}
mslqvnllnntfanpfmnaagvmcttteelvamtesasgslvsksctpalregnptpryq
alplgsinsmglpnngfdfylayaaeqhdygkkplflsmsglsmrenvemckrlaavate
kgvilelnlsdfdamrqcltavsevyphsfgvkmppyfdfahfdaaaeilnefpkvqfit
cinsignglvidaetesvvikpkqgfgglggryvlptalaninafyrrcpgklifgcggv
ytgedaflhvlagasmvqvgtalqeegpsiferltsellgvmakkryqtldefrgkvrtl
d

Timeline for d6dgsb1:

• d6dgsb1 first appeared in SCOPe 2.07