Lineage for d1daja_ (1daj A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2136820Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 2136821Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. 2136822Family c.71.1.1: Dihydrofolate reductases [53598] (4 protein domains)
  6. 2137011Protein Dihydrofolate reductases, eukaryotic type [53605] (7 species)
  7. 2137033Species Fungus (Pneumocystis carinii) [TaxId:4754] [53608] (25 PDB entries)
  8. 2137056Domain d1daja_: 1daj A: [34921]
    complexed with mot, ndp

Details for d1daja_

PDB Entry: 1daj (more details), 2.3 Å

PDB Description: comparison of ternary complexes of pneumocystis carinii and wild type human dihydrofolate reductase with coenzyme nadph and a novel classical antitumor furo[2,3d]pyrimidine antifolate
PDB Compounds: (A:) dihydrofolate reductase

SCOPe Domain Sequences for d1daja_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1daja_ c.71.1.1 (A:) Dihydrofolate reductases, eukaryotic type {Fungus (Pneumocystis carinii) [TaxId: 4754]}

SCOPe Domain Coordinates for d1daja_:

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Timeline for d1daja_: