SCOPe 2.08: Domain d5wg4a2: 5wg4 A:186-548

Lineage for d5wg4a2 (5wg4 A:186-548)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d5wg4a2: 5wg4 A:186-548 [348532]
   Other proteins in same PDB: d5wg4a1, d5wg4a3, d5wg4b_, d5wg4g_
   automated match to d3v5wa2
   complexed with afv

Details for d5wg4a2

PDB Entry: 5wg4, 2.31 Å

PDB Description: human grk2 in complex with gbetagamma subunits and ccg257284

PDB Compounds: (A:) Beta-adrenergic receptor kinase 1

SCOPe Domain Sequences for d5wg4a2:

Sequence, based on SEQRES records:

>d5wg4a2 d.144.1.7 (A:186-548) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ltmndfsvhriigrggfgevygcrkadtgkmyamkcldkkrikmkqgetlalnerimlsl
vstgdcpfivcmsyafhtpdklsfildlmnggdlhyhlsqhgvfseadmrfyaaeiilgl
ehmhnrfvvyrdlkpanilldehghvrisdlglacdfskkkphasvgthgymapevlqkg
vaydssadwfslgcmlfkllrghspfrqhktkdkheidrmtltmavelpdsfspelrsll
egllqrdvnrrlgclgrgaqevkespffrsldwqmvflqkyppplipprgevnaadafdi
gsfdeedtkgiklldsdqelyrnfpltiserwqqevaetvfdtinaetdrlearkkaknk
qlg

Sequence, based on observed residues (ATOM records):

>d5wg4a2 d.144.1.7 (A:186-548) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ltmndfsvhriigrggfgevygcrkadtgkmyamkcldkkrikmkqgetlalnerimlsl
vstgdcpfivcmsyafhtpdklsfildlmnggdlhyhlsqhgvfseadmrfyaaeiilgl
ehmhnrfvvyrdlkpanilldehghvrisdlglacdfskkkphasvgthgymapevlqkg
vaydssadwfslgcmlfkllrghspfrqhktkdkheidrmtltvelpdsfspelrslleg
llqrdvnrrlgclgrgaqevkespffrsldwqmvflqkyppplipprgevnaadatkgik
lldsdqelyrnfpltiserwqqevaetvfdtinaetdrlearkkaknkqlg

Timeline for d5wg4a2:

• d5wg4a2 first appeared in SCOPe 2.07