SCOPe 2.08: Domain d5w9db_: 5w9d B:

Lineage for d5w9db_ (5w9d B:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Estrogen receptor alpha [48519] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48520] (107 PDB entries)
   Uniprot P03372 307-551

8. Domain d5w9db_: 5w9d B: [340165]
   automated match to d3erta_
   complexed with 9xy; mutant

Details for d5w9db_

PDB Entry: 5w9d, 1.65 Å

PDB Description: estrogen receptor alpha ligand binding domain c381s, c417s, c530s mutant in complex with endoxifen

PDB Compounds: (B:) Estrogen receptor

SCOPe Domain Sequences for d5w9db_:

Sequence, based on SEQRES records:

>d5w9db_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
alsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvpg
fvdltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmveifd
mllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdtl
ihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmksknvvpsydlllemld

Sequence, based on observed residues (ATOM records):

>d5w9db_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
alsltadqmvsalldaeppilyseydptrpfssmmglltnladrelvhminwakrvpgfv
dltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmveifdml
latssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdtlih
lmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmksknvvpsydlllemld

Timeline for d5w9db_:

• d5w9db_ first appeared in SCOPe 2.06
  
• d5w9db_ appears in SCOPe 2.07