Lineage for d5w9db_ (5w9d B:)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2335122Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
    multihelical; 3 layers or orthogonally packed helices
  4. 2335123Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families) (S)
  5. 2335124Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)
  6. 2335233Protein Estrogen receptor alpha [48519] (1 species)
  7. 2335234Species Human (Homo sapiens) [TaxId:9606] [48520] (71 PDB entries)
    Uniprot P03372 307-551
  8. 2335256Domain d5w9db_: 5w9d B: [340165]
    automated match to d3erta_
    complexed with 9xy; mutant

Details for d5w9db_

PDB Entry: 5w9d (more details), 1.65 Å

PDB Description: estrogen receptor alpha ligand binding domain c381s, c417s, c530s mutant in complex with endoxifen
PDB Compounds: (B:) Estrogen receptor

SCOPe Domain Sequences for d5w9db_:

Sequence, based on SEQRES records: (download)

>d5w9db_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
alsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvpg
fvdltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmveifd
mllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdtl
ihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmksknvvpsydlllemld

Sequence, based on observed residues (ATOM records): (download)

>d5w9db_ a.123.1.1 (B:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
alsltadqmvsalldaeppilyseydptrpfssmmglltnladrelvhminwakrvpgfv
dltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmveifdml
latssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdtlih
lmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmksknvvpsydlllemld

SCOPe Domain Coordinates for d5w9db_:

Click to download the PDB-style file with coordinates for d5w9db_.
(The format of our PDB-style files is described here.)

Timeline for d5w9db_: