SCOPe 2.08: Domain d4cjyc_: 4cjy C:

Lineage for d4cjyc_ (4cjy C:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (37 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1476 PDB entries)

8. Domain d4cjyc_: 4cjy C: [307123]
   Other proteins in same PDB: d4cjya1, d4cjya2, d4cjyb1, d4cjyb2
   automated match to d4nsta_

Details for d4cjyc_

PDB Entry: 4cjy, 3.15 Å

PDB Description: Crystal structure of the human CDK12-cyclinK complex

PDB Compounds: (C:) cyclin-dependent kinase 12

SCOPe Domain Sequences for d4cjyc_:

Sequence, based on SEQRES records:

>d4cjyc_ d.144.1.0 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
wgkrcvdkfdiigiigegtygqvykakdkdtgelvalkkvrldnekegfpitaireikil
rqlihrsvvnmkeivtdkqdaldfkkdkgafylvfeymdhdlmgllesglvhfsedhiks
fmkqlmegleychkknflhrdikcsnillnnsgqikladfglarlynseesrpytnkvit
lwyrppelllgeerytpaidvwscgcilgelftkkpifqanlelaqlelisrlcgspcpa
vwpdviklpyfntmkpkkqyrrrlreefsfipsaaldlldhmltldpskrctaeqtlqsd
flkdvelskmapp

Sequence, based on observed residues (ATOM records):

>d4cjyc_ d.144.1.0 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
wgkrcvdkfdiigiigegtygqvykakdkdtgelvalkkvrldnekegfpitaireikil
rqlihrsvvnmkeivtdkkdkgafylvfeymdhdlmgllesglvhfsedhiksfmkqlme
gleychkknflhrdikcsnillnnsgqikladfglarlynseesrpytnkvitlwyrppe
lllgeerytpaidvwscgcilgelftkkpifqanlelaqlelisrlcgspcpavwpdvik
lpyfntmkpqyrrrlreefsfipsaaldlldhmltldpskrctaeqtlqsdflkdvelsk
mapp

Timeline for d4cjyc_:

• d4cjyc_ first appeared in SCOPe 2.06
  
• d4cjyc_ appears in SCOPe 2.07