SCOP 1.63: Domain d1emd_1: 1emd 1-145

Lineage for d1emd_1 (1emd 1-145)

1. Root: SCOP 1.63

2. Class c: Alpha and beta proteins (a/b) [51349] (117 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (10 families)

5. Family c.2.1.5: Lactate & malate dehydrogenases, N-terminal domain [51848] (4 proteins)

6. Protein Malate dehydrogenase [51849] (11 species)

7. Species Escherichia coli [TaxId:562] [51853] (4 PDB entries)

8. Domain d1emd_1: 1emd 1-145 [30136]
   Other proteins in same PDB: d1emd_2
   complexed with cit, nad

Details for d1emd_1

PDB Entry: 1emd, 1.9 Å

PDB Description: crystal structure of a ternary complex of escherichia coli malate dehydrogenase, citrate and nad at 1.9 angstroms resolution

SCOP Domain Sequences for d1emd_1:

Sequence; same for both SEQRES and ATOM records:

>d1emd_1 c.2.1.5 (1-145) Malate dehydrogenase {Escherichia coli}
mkvavlgaaggigqalalllktqlpsgselslydiapvtpgvavdlshiptavkikgfsg
edatpalegadvvlisagvrrkpgmdrsdlfnvnagivknlvqqvaktcpkacigiitnp
vnttvaiaaevlkkagvydknklfg

Timeline for d1emd_1:

• d1emd_1 first appeared (with stable ids) in SCOP 1.55
  
• d1emd_1 appears in SCOP 1.61
  
• d1emd_1 appears in SCOP 1.65
  
• d1emd_1 appears in the current release, SCOPe 2.08, called d1emda1