Lineage for d1dy9.2 (1dy9 B:,D:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2055629Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 2055630Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 2057706Family b.47.1.3: Viral proteases [50596] (5 protein domains)
    beta sheet in the first domain is opened rather than forms a barrel
  6. 2057707Protein NS3 protease [50600] (5 species)
  7. 2057717Species Human hepatitis C virus (HCV), different isolates [TaxId:11103] [50601] (14 PDB entries)
    Uniprot P27958 1027-1206,1678-1669
    Uniprot P26662 1029-1202,1677-1689
    Uniprot O36579 1054-1207
  8. 2057719Domain d1dy9.2: 1dy9 B:,D: [26401]
    complexed with 2zf, zn

Details for d1dy9.2

PDB Entry: 1dy9 (more details), 2.1 Å

PDB Description: inhibition of the hepatitis c virus ns3/4a protease. the crystal structures of two protease-inhibitor complexes (inhibitor i)
PDB Compounds: (B:) protease/helicase ns3 (p70), (D:) nonstructural protein ns4a (p4)

SCOPe Domain Sequences for d1dy9.2:

Sequence; same for both SEQRES and ATOM records: (download)

>g1dy9.2 b.47.1.3 (B:,D:) NS3 protease {Human hepatitis C virus (HCV), different isolates [TaxId: 11103]}

SCOPe Domain Coordinates for d1dy9.2:

Click to download the PDB-style file with coordinates for d1dy9.2.
(The format of our PDB-style files is described here.)

Timeline for d1dy9.2: