Lineage for Species: Human hepatitis C virus (HCV), different isolates [TaxId: 11103]

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2055629Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 2055630Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 2057706Family b.47.1.3: Viral proteases [50596] (5 protein domains)
    beta sheet in the first domain is opened rather than forms a barrel
  6. 2057707Protein NS3 protease [50600] (5 species)
  7. 2057717Species Human hepatitis C virus (HCV), different isolates [TaxId:11103] [50601] (14 PDB entries)
    Uniprot P27958 1027-1206,1678-1669
    Uniprot P26662 1029-1202,1677-1689
    Uniprot O36579 1054-1207

PDB entries in Species: Human hepatitis C virus (HCV), different isolates [TaxId: 11103]:

  1. Domain(s) for 1a1q:
    1. 2057736Domain d1a1qa_: 1a1q A: [26414]
      complexed with zn
    2. 2057737Domain d1a1qb_: 1a1q B: [26415]
      complexed with zn
    3. 2057738Domain d1a1qc_: 1a1q C: [26416]
      complexed with zn
  2. Domain(s) for 1a1r:
    1. 2057724Domain d1a1r.1: 1a1r A:,C: [26406]
      complexed with zn
    2. 2057725Domain d1a1r.2: 1a1r B:,D: [26407]
      complexed with zn
  3. Domain(s) for 1bt7:
  4. Domain(s) for 1cu1:
    1. 2057728Domain d1cu1a1: 1cu1 A:705-720,A:3-186 [26408]
      Other proteins in same PDB: d1cu1a2, d1cu1a3, d1cu1b2, d1cu1b3
      complexed with po4, zn
    2. 2057729Domain d1cu1b1: 1cu1 B:1705-1720,B:1003-1186 [26409]
      Other proteins in same PDB: d1cu1a2, d1cu1a3, d1cu1b2, d1cu1b3
      complexed with po4, zn
  5. Domain(s) for 1dxp:
    1. 2057730Domain d1dxp.1: 1dxp A:,C: [26404]
      complexed with gol, zn
    2. 2057731Domain d1dxp.2: 1dxp B:,D: [26405]
      complexed with gol, zn
  6. Domain(s) for 1dxw:
  7. Domain(s) for 1dy8:
    1. 2057732Domain d1dy8.1: 1dy8 A:,C: [26410]
      complexed with 0f7
    2. 2057733Domain d1dy8.2: 1dy8 B:,D: [26411]
      complexed with 0f7
  8. Domain(s) for 1dy9:
    1. 2057718Domain d1dy9.1: 1dy9 A:,C: [26400]
      complexed with 2zf, zn
    2. 2057719Domain d1dy9.2: 1dy9 B:,D: [26401]
      complexed with 2zf, zn
  9. Domain(s) for 1jxp:
    1. 2057720Domain d1jxp.1: 1jxp A:,C: [26402]
      complexed with zn
    2. 2057721Domain d1jxp.2: 1jxp B:,D: [26403]
      complexed with zn
  10. Domain(s) for 1n1l:
    1. 2057722Domain d1n1l.1: 1n1l A:,C: [91544]
      complexed with trl, zn
    2. 2057723Domain d1n1l.2: 1n1l B:,D: [91545]
      complexed with trl, zn
  11. Domain(s) for 1ns3:
    1. 2057734Domain d1ns3.1: 1ns3 A:,C: [26412]
      complexed with zn
    2. 2057735Domain d1ns3.2: 1ns3 B:,D: [26413]
      complexed with zn
  12. Domain(s) for 1rgq:
    1. 2057741Domain d1rgq.1: 1rgq A:,D: [111803]
      complexed with akp, zn
    2. 2057742Domain d1rgq.2: 1rgq B:,C: [111804]
      complexed with akp, zn
  13. Domain(s) for 1rtl:
    1. 2057726Domain d1rtl.1: 1rtl A:,C: [111934]
      complexed with cpx, zn
    2. 2057727Domain d1rtl.2: 1rtl B:,D: [144371]
      complexed with cpx, zn
  14. Domain(s) for 1w3c:
    1. 2057739Domain d1w3c.1: 1w3c A:,C: [114138]
      complexed with dn1, dn2
    2. 2057740Domain d1w3c.2: 1w3c B:,D: [114139]
      complexed with dn1, dn2

More info for Species Human hepatitis C virus (HCV), different isolates [TaxId:11103] from b.47.1.3 NS3 protease

Timeline for Species Human hepatitis C virus (HCV), different isolates [TaxId:11103] from b.47.1.3 NS3 protease: