SCOPe 2.04: Domain d4cq8a_: 4cq8 A:

Lineage for d4cq8a_ (4cq8 A:)

1. Root: SCOPe 2.04

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.4: FMN-linked oxidoreductases [51395] (2 families)

5. Family c.1.4.1: FMN-linked oxidoreductases [51396] (19 proteins)

6. Protein automated matches [190228] (14 species)
   not a true protein

7. Species Plasmodium falciparum [TaxId:5833] [256645] (1 PDB entry)

8. Domain d4cq8a_: 4cq8 A: [256646]
   automated match to d1tv5a1
   complexed with fmn, jbw, oro

Details for d4cq8a_

PDB Entry: 4cq8, 1.98 Å

PDB Description: plasmodium falciparum dihydroorotate dehydrogenase (dhodh) in complex with genz-669178

PDB Compounds: (A:) dihydroorotate dehydrogenase

SCOPe Domain Sequences for d4cq8a_:

Sequence, based on SEQRES records:

>d4cq8a_ c.1.4.1 (A:) automated matches {Plasmodium falciparum [TaxId: 5833]}
adpfesynpefflydiflkfclkyidgeichdlflllgkynilpydtsndsiyactnikh
ldfinpfgvaagfdkngvcidsilklgfsfieigtitprgqtgnakprifrdvesrsiin
scgfnnmgcdkvtenlilfrkrqeedkllskhivgvsigknkdtvnivddlkycinkigr
yadyiainvsspntpglrdnqeagklkniilsvkeeidnleknnimndeflwfnttkkkp
lvfvklapdlnqeqkkeiadvlletnidgmiisntttqindiksfenkkggvsgaklkdi
stkficemynytnkqipiiasggifsgldalekieagasvcqlysclvfngmksavqikr
elnhllyqrgyynlkeaigrkhs

Sequence, based on observed residues (ATOM records):

>d4cq8a_ c.1.4.1 (A:) automated matches {Plasmodium falciparum [TaxId: 5833]}
adpfesynpefflydiflkfclkyidgeichdlflllgkynilpydtsndsiyactnikh
ldfinpfgvaagfdkngvcidsilklgfsfieigtitprgqtgnakprifrdvesrsiin
scgfnnmgcdkvtenlilfrkrqeedkllskhivgvsigknkdtvnivddlkycinkigr
yadyiainvsspntpglrdnqeagklkniilsvkeeidnleknnflwfnttkkkplvfvk
lapdlnqeqkkeiadvlletnidgmiisntttqindiksfenkkggvsgaklkdistkfi
cemynytnkqipiiasggifsgldalekieagasvcqlysclvfngmksavqikrelnhl
lyqrgyynlkeaigrkhs

Timeline for d4cq8a_:

• d4cq8a_ is new in SCOPe 2.04-stable
  
• d4cq8a_ appears in SCOPe 2.05
  
• d4cq8a_ appears in the current release, SCOPe 2.08, called d4cq8a1