SCOPe 2.04: Domain d4dkta3: 4dkt A:294-663

Lineage for d4dkta3 (4dkt A:294-663)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.126: Pentein, beta/alpha-propeller [55908] (1 superfamily)
   duplication: composed of 5 alpha-beta(2)-alpha-beta units arranged around pseudo fivefold axis

4. Superfamily d.126.1: Pentein [55909] (8 families)

5. Family d.126.1.5: Peptidylarginine deiminase Pad4, catalytic C-terminal domain [111152] (1 protein)
   # functionally related to the amidinotransferase, similar active sites
   automatically mapped to Pfam PF03068

6. Protein Peptidylarginine deiminase Pad4, catalytic C-terminal domain [111153] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [111154] (12 PDB entries)
   Uniprot Q9UM07

8. Domain d4dkta3: 4dkt A:294-663 [251476]
   Other proteins in same PDB: d4dkta1, d4dkta2
   automated match to d1wd8a3
   complexed with ca, edo, so4

Details for d4dkta3

PDB Entry: 4dkt, 2.98 Å

PDB Description: crystal structure of human peptidylarginine deiminase 4 in complex with n-acetyl-l-threonyl-l-alpha-aspartyl-n5-[(1e)-2- fluoroethanimidoyl]-l-ornithinamide

PDB Compounds: (A:) Protein-arginine deiminase type-4

SCOPe Domain Sequences for d4dkta3:

Sequence, based on SEQRES records:

>d4dkta3 d.126.1.5 (A:294-663) Peptidylarginine deiminase Pad4, catalytic C-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
apwimtpntqppqevyacsifenedflksvttlamkakcklticpeeenmddqwmqdeme
igyiqaphktlpvvfdsprnrglkefpikrvmgpdfgyvtrgpqtggisgldsfgnlevs
ppvtvrgkeyplgrilfgdscypsndsrqmhqalqdflsaqqvqapvklysdwlsvghvd
eflsfvpapdrkgfrlllasprscyklfqeqqneghgeallfegikkkkqqkiknilsnk
tlrehnsfvercidwnrellkrelglaesdiidipqlfklkefskaeaffpnmvnmlvlg
khlgipkpfgpvingrccleekvcslleplglqctfindfftyhirhgevhcgtnvrrkp
fsfkwwnmvp

Sequence, based on observed residues (ATOM records):

>d4dkta3 d.126.1.5 (A:294-663) Peptidylarginine deiminase Pad4, catalytic C-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
apwimtpntqppqevyacedflksvttlamkakcklticpeeenmddqwmqdemeigyiq
aphktlpvvfdsprnrglkefpikrvmgpdfgyvtrgpqtggisgldsfgnlevsppvtv
rgkeyplgrilfgdscypsndsrqmhqalqdflsaqqvqapvklysdwlsvghvdeflsf
vpapdrkgfrlllasprscyklfqeqqneghgeallfegikkkkqqkiknilsnktlreh
nsfvercidwnrellkrelglaesdiidipqlfklkefskaeaffpnmvnmlvlgkhlgi
pkpfgpvingrccleekvcslleplglqctfindfftyhirhgevhcgtnvrrkpfsfkw
wnmvp

Timeline for d4dkta3:

• d4dkta3 is new in SCOPe 2.04-stable
  
• d4dkta3 appears in SCOPe 2.05
  
• d4dkta3 appears in the current release, SCOPe 2.08