SCOPe 2.08: Domain d2d4ha1: 2d4h A:5-283

Lineage for d2d4ha1 (2d4h A:5-283)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (81 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein automated matches [190047] (37 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [186768] (291 PDB entries)

8. Domain d2d4ha1: 2d4h A:5-283 [241501]
   Other proteins in same PDB: d2d4ha2, d2d4hb2
   automated match to d2b8wb1
   complexed with 5gp

Details for d2d4ha1

PDB Entry: 2d4h, 2.9 Å

PDB Description: crystal-structure of the n-terminal large gtpase domain of human guanylate binding protein 1 (hgbp1) in complex with gmp

PDB Compounds: (A:) interferon-induced guanylate-binding protein 1

SCOPe Domain Sequences for d2d4ha1:

Sequence, based on SEQRES records:

>d2d4ha1 c.37.1.8 (A:5-283) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ihmtgpmclientngrlmanpealkilsaitqpmvvvaivglyrtgksylmnklagkkkg
fslgstvqshtkgiwmwcvphpkkpghilvlldteglgdvekgdnqndswifalavllss
tfvynsigtinqqamdqlyyvtelthrirsksspdenenevedsadfvsffpdfvwtlrd
fsldleadgqpltpdeyltyslklkkgtsqkdetfnlprlcirkffpkkkcfvfdrpvhr
rklaqleklqdeeldpefvqqvadfcsyifsnsktktls

Sequence, based on observed residues (ATOM records):

>d2d4ha1 c.37.1.8 (A:5-283) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ihmtgpmclientngrlmanpealkilsaitqpmvvvaivglyrtgksylmnklagkkkg
fslgstvqkgiwmwcvphpkkpghilvlldteglgdvenqndswifalavllsstfvyns
igtinqqamdqlyyvtelthrirsksspdesadfvsffpdfvwtlrdfsldleadgqplt
pdeyltyslklkkgtsqkdetfnlprlcirkffpkkkcfvfdrpvhrrklaqleklqdee
ldpefvqqvadfcsyifsnsktktls

Timeline for d2d4ha1:

• d2d4ha1 first appeared in SCOPe 2.04
  
• d2d4ha1 appears in SCOPe 2.07