Lineage for d3sfia2 (3sfi A:95-214)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2334734Fold a.121: Tetracyclin repressor-like, C-terminal domain [48497] (1 superfamily)
    multihelical; interlocked (homo)dimer
  4. 2334735Superfamily a.121.1: Tetracyclin repressor-like, C-terminal domain [48498] (2 families) (S)
  5. 2334736Family a.121.1.1: Tetracyclin repressor-like, C-terminal domain [48499] (35 proteins)
  6. 2335065Protein automated matches [226970] (6 species)
    not a true protein
  7. 2335096Species Mycobacterium tuberculosis [TaxId:1773] [232226] (7 PDB entries)
  8. 2335103Domain d3sfia2: 3sfi A:95-214 [238508]
    Other proteins in same PDB: d3sfia1
    automated match to d3g1ma2
    protein/DNA complex; complexed with 3sf

Details for d3sfia2

PDB Entry: 3sfi (more details), 2.31 Å

PDB Description: ethionamide boosters part 2: combining bioisosteric replacement and structure-based drug design to solve pharmacokinetic issues in a series of potent 1,2,4-oxadiazole ethr inhibitors.
PDB Compounds: (A:) Transcriptional regulatory repressor protein (TETR-family)

SCOPe Domain Sequences for d3sfia2:

Sequence; same for both SEQRES and ATOM records: (download)

>d3sfia2 a.121.1.1 (A:95-214) automated matches {Mycobacterium tuberculosis [TaxId: 1773]}
adtdrenmwrtginvffetfgshkavtragqaaratsvevaelwstfmqkwiaytaavid
aerdrgaaprtlpahelatalnlmnertlfasfageqpsvpearvldtlvhiwvtsiyge

SCOPe Domain Coordinates for d3sfia2:

Click to download the PDB-style file with coordinates for d3sfia2.
(The format of our PDB-style files is described here.)

Timeline for d3sfia2:

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Domains from same chain:
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d3sfia1