SCOPe 2.07: Domain d4g4sn_: 4g4s N:

Lineage for d4g4sn_ (4g4s N:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.153: Ntn hydrolase-like [56234] (2 superfamilies)
   4 layers: alpha/beta/beta/alpha; has an unusual sheet-to-sheet packing

4. Superfamily d.153.1: N-terminal nucleophile aminohydrolases (Ntn hydrolases) [56235] (8 families)
   N-terminal residue provides two catalytic groups, nucleophile and proton donor

5. Family d.153.1.4: Proteasome subunits [56251] (4 proteins)

6. Protein Proteasome beta subunit (catalytic) [56252] (7 species)

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56254] (202 PDB entries)
   The structure of yeast proteasome complexed with the proteasome activator pa26 is available from PDB (1fnt). The 1FNT entry designates protein chains by both upper case and lower case letters creating problems with its processing and presentation in SCOP; the proteasome activator pa26 structure is classified elsewhere in SCOP (a.24.8)

8. Domain d4g4sn_: 4g4s N: [202192]
   Other proteins in same PDB: d4g4sa_, d4g4sc_, d4g4sd_, d4g4se_, d4g4sf_, d4g4sg_, d4g4si_, d4g4sl_
   automated match to d1rypn_
   complexed with ldz, mg

Details for d4g4sn_

PDB Entry: 4g4s, 2.49 Å

PDB Description: Structure of Proteasome-Pba1-Pba2 Complex

PDB Compounds: (N:) Proteasome component PRE4

SCOPe Domain Sequences for d4g4sn_:

Sequence; same for both SEQRES and ATOM records:

>d4g4sn_ d.153.1.4 (N:) Proteasome beta subunit (catalytic) {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
tqqpivtgtsvismkydngviiaadnlgsygsllrfngverlipvgdntvvgisgdisdm
qhierllkdlvtenaydnpladaeealepsyifeylatvmyqrrskmnplwnaiivagvq
sngdqflryvnllgvtyssptlatgfgahmanpllrkvvdresdipkttvqvaeeaivna
mrvlyyrdarssrnfslaiidkntgltfkknlqvenmkwdfakdikgygtqki

Timeline for d4g4sn_:

• d4g4sn_ first appeared in SCOPe 2.03
  
• d4g4sn_ appears in SCOPe 2.06
  
• d4g4sn_ appears in the current release, SCOPe 2.08