Lineage for d4fabh1 (4fab H:1-118)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2017115Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2017116Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2017117Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 protein domains)
  6. 2017323Protein Immunoglobulin heavy chain variable domain, VH [88543] (21 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 2017580Species Mouse (Mus musculus), cluster 1 [TaxId:10090] [88548] (68 PDB entries)
    Uniprot P01796 # ! HV27_MOUSE Ig heavy chain V-III region A4
  8. 2017659Domain d4fabh1: 4fab H:1-118 [19907]
    Other proteins in same PDB: d4fabh2, d4fabl1, d4fabl2
    part of Fab 4-4-20
    complexed with fds, mpd

Details for d4fabh1

PDB Entry: 4fab (more details), 2.7 Å

PDB Description: three-dimensional structure of a fluorescein-fab complex crystallized in 2-methyl-2,4-pentanediol
PDB Compounds: (H:) igg2a-kappa 4-4-20 fab (heavy chain)

SCOPe Domain Sequences for d4fabh1:

Sequence; same for both SEQRES and ATOM records: (download)

>d4fabh1 b.1.1.1 (H:1-118) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 1 [TaxId: 10090]}

SCOPe Domain Coordinates for d4fabh1:

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Timeline for d4fabh1:

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