Class b: All beta proteins [48724] (180 folds) |
Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies) sandwich; 7 strands in 2 sheets; greek-key some members of the fold have additional strands |
Superfamily b.1.1: Immunoglobulin [48726] (5 families) |
Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins) |
Protein Immunoglobulin heavy chain variable domain, VH [88543] (22 species) VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species |
Species Mouse (Mus musculus), cluster 1 [TaxId:10090] [88548] (68 PDB entries) Uniprot P01796 # ! HV27_MOUSE Ig heavy chain V-III region A4 |
Domain d1axth1: 1axt H:1-113 [20305] Other proteins in same PDB: d1axth2, d1axtl1, d1axtl2 part of catalytic Fab 33F12 with an aldolase activity |
Domain d1cbvh1: 1cbv H:1-122 [19901] Other proteins in same PDB: d1cbvh2, d1cbvl1, d1cbvl2 part of Fab BV04-01 protein/DNA complex |
Domain d1ck0h1: 1ck0 H:6-117 [90422] Other proteins in same PDB: d1ck0h2, d1ck0h3, d1ck0l1, d1ck0l2 part of anti-anti-idiotypic Fab against human angiotensin II, unliganded form |
Domain d1cloh1: 1clo H:1-113 [20123] Other proteins in same PDB: d1cloh2, d1clol1, d1clol2 part of Fab A5B7 |
Domain d1dlfh_: 1dlf H: [20383] Other proteins in same PDB: d1dlfl_ part of anti-dansyl Fv complexed with so4 |
Domain d1fl5b1: 1fl5 B:1-113 [65017] Other proteins in same PDB: d1fl5a1, d1fl5a2, d1fl5b2, d1fl5h2, d1fl5l1, d1fl5l2 part of humanized catalytic Fab 28b4 with a sulfide oxidase activity complexed with so4 |
Domain d1fl5h1: 1fl5 H:1-113 [65019] Other proteins in same PDB: d1fl5a1, d1fl5a2, d1fl5b2, d1fl5h2, d1fl5l1, d1fl5l2 part of humanized catalytic Fab 28b4 with a sulfide oxidase activity complexed with so4 |
Domain d1fl6b1: 1fl6 B:1-113 [65025] Other proteins in same PDB: d1fl6a1, d1fl6a2, d1fl6b2, d1fl6h2, d1fl6l1, d1fl6l2 part of humanized catalytic Fab 28b4 with a sulfide oxidase activity complexed with aah |
Domain d1fl6h1: 1fl6 H:1-113 [65027] Other proteins in same PDB: d1fl6a1, d1fl6a2, d1fl6b2, d1fl6h2, d1fl6l1, d1fl6l2 part of humanized catalytic Fab 28b4 with a sulfide oxidase activity complexed with aah |
Domain d1flrh1: 1flr H:1-118 [19905] Other proteins in same PDB: d1flrh2, d1flrl1, d1flrl2 part of Fab 4-4-20 complexed with flu |
Domain d1kelh1: 1kel H:1-119 [20113] Other proteins in same PDB: d1kelh2, d1kell1, d1kell2 part of Fab 28B4 complexed with aah |
Domain d1kemh1: 1kem H:1-119 [20115] Other proteins in same PDB: d1kemh2, d1keml1, d1keml2 part of Fab 28B4 |
Domain d1m71b1: 1m71 B:1-113 [84853] Other proteins in same PDB: d1m71a1, d1m71a2, d1m71b2 part of Fab specific for Y lipopolysaccharide |
Domain d1m7db1: 1m7d B:1-113 [84863] Other proteins in same PDB: d1m7da1, d1m7da2, d1m7db2 part of Fab specific for Y lipopolysaccharide |
Domain d1m7ib1: 1m7i B:1-113 [84867] Other proteins in same PDB: d1m7ia1, d1m7ia2, d1m7ib2 part of Fab specific for Y lipopolysaccharide |
Domain d1mamh1: 1mam H:1-119 [19887] Other proteins in same PDB: d1mamh2, d1maml1, d1maml2 part of Fab Yst9.1 |
Domain d1mcph1: 1mcp H:1-121 [19859] Other proteins in same PDB: d1mcph2, d1mcpl1, d1mcpl2 part of Fab MCPC603 complexed with so4 |
Domain d1nbvh1: 1nbv H:1-122 [19899] Other proteins in same PDB: d1nbvh2, d1nbvl1, d1nbvl2 part of Fab BV04-01 protein/DNA complex |
Domain d1pz5b1: 1pz5 B:1-113 [95403] Other proteins in same PDB: d1pz5a1, d1pz5a2, d1pz5b2 part of Fab Sya/J6 |
Domain d1q72h1: 1q72 H:1-113 [96014] Other proteins in same PDB: d1q72h2, d1q72l1, d1q72l2 part of anti-cocaine Fab M82G2 complexed with coc |
Domain d1q9kb1: 1q9k B:1-111 [96278] Other proteins in same PDB: d1q9ka1, d1q9ka2, d1q9kb2 part of Fab s25-2 complexed with mg |
Domain d1q9lb1: 1q9l B:1-111 [96282] Other proteins in same PDB: d1q9la1, d1q9la2, d1q9lb2, d1q9lc1, d1q9lc2, d1q9ld2 part of Fab s25-2 complexed with mg, zn |
Domain d1q9ld1: 1q9l D:1-111 [96286] Other proteins in same PDB: d1q9la1, d1q9la2, d1q9lb2, d1q9lc1, d1q9lc2, d1q9ld2 part of Fab s25-2 complexed with mg, zn |
Domain d1q9ob1: 1q9o B:1-111 [96294] Other proteins in same PDB: d1q9oa1, d1q9oa2, d1q9ob2, d1q9oc1, d1q9oc2, d1q9od2 part of Fab s45-18 complexed with mg |
Domain d1q9od1: 1q9o D:1-111 [96298] Other proteins in same PDB: d1q9oa1, d1q9oa2, d1q9ob2, d1q9oc1, d1q9oc2, d1q9od2 part of Fab s45-18 complexed with mg |
Domain d1q9qb3: 1q9q B:1-111 [302914] Other proteins in same PDB: d1q9qa3, d1q9qa4, d1q9qb4 automated match to d3t65b1 complexed with mg, zn |
Domain d1q9rb3: 1q9r B:1-111 [302918] Other proteins in same PDB: d1q9ra3, d1q9ra4, d1q9rb4 automated match to d3t65b1 complexed with mg, zn |
Domain d1q9tb3: 1q9t B:1-111 [302922] Other proteins in same PDB: d1q9ta3, d1q9ta4, d1q9tb4 automated match to d3t77b1 complexed with mg, zn |
Domain d1q9vb3: 1q9v B:1-111 [302926] Other proteins in same PDB: d1q9va3, d1q9va4, d1q9vb4 automated match to d3t65b1 complexed with kdo, mg, zn |
Domain d1q9wb1: 1q9w B:1-111 [96322] Other proteins in same PDB: d1q9wa1, d1q9wa2, d1q9wb2, d1q9wc1, d1q9wc2, d1q9wd2 part of Fab s45-18 complexed with mg |
Domain d1q9wd1: 1q9w D:1-111 [96326] Other proteins in same PDB: d1q9wa1, d1q9wa2, d1q9wb2, d1q9wc1, d1q9wc2, d1q9wd2 part of Fab s45-18 complexed with mg |
Domain d1qygh1: 1qyg H:1-113 [96589] Other proteins in same PDB: d1qygh2, d1qygl1, d1qygl2 part of anti-cocaine Fab M82G2 complexed with bcg |
Domain d1rfdh1: 1rfd H:1-113 [97372] Other proteins in same PDB: d1rfdh2, d1rfdl1, d1rfdl2 part of anti-cocaine Fab M82G2 |
Domain d1riuh1: 1riu H:1-113 [97518] Other proteins in same PDB: d1riuh2, d1riul1, d1riul2 part of anti-cocaine Fab M82G2 complexed with rbe |
Domain d1rivh1: 1riv H:1-113 [97522] Other proteins in same PDB: d1rivh2, d1rivl1, d1rivl2 part of anti-cocaine Fab M82G2 complexed with obe |
Domain d1sbsh1: 1sbs H:1-123 [20367] Other proteins in same PDB: d1sbsh2, d1sbsl1, d1sbsl2 part of anti-HCG Fab 3A2 complexed with so4 |
Domain d1sm3h1: 1sm3 H:2-113 [20369] Other proteins in same PDB: d1sm3h2, d1sm3h3, d1sm3l1, d1sm3l2 part of tumor-specific Fab SM3 against epithelial mucin Muc1 complexed with cd, cl |
Domain d1v7mh1: 1v7m H:1-116 [100450] Other proteins in same PDB: d1v7mh2, d1v7mi2, d1v7ml1, d1v7ml2, d1v7mm1, d1v7mm2, d1v7mv_, d1v7mx_ part of anti-trombopoetin Fab tn1 |
Domain d1v7mi1: 1v7m I:1-116 [100452] Other proteins in same PDB: d1v7mh2, d1v7mi2, d1v7ml1, d1v7ml2, d1v7mm1, d1v7mm2, d1v7mv_, d1v7mx_ part of anti-trombopoetin Fab tn1 |
Domain d1v7nh1: 1v7n H:1-116 [100460] Other proteins in same PDB: d1v7nh2, d1v7ni2, d1v7nj2, d1v7nk2, d1v7nl1, d1v7nl2, d1v7nm1, d1v7nm2, d1v7nn1, d1v7nn2, d1v7no1, d1v7no2, d1v7nv_, d1v7nx_, d1v7ny_, d1v7nz_ part of anti-trombopoetin Fab tn1 |
Domain d1v7ni1: 1v7n I:1-116 [100462] Other proteins in same PDB: d1v7nh2, d1v7ni2, d1v7nj2, d1v7nk2, d1v7nl1, d1v7nl2, d1v7nm1, d1v7nm2, d1v7nn1, d1v7nn2, d1v7no1, d1v7no2, d1v7nv_, d1v7nx_, d1v7ny_, d1v7nz_ part of anti-trombopoetin Fab tn1 |
Domain d1v7nj1: 1v7n J:1-116 [100464] Other proteins in same PDB: d1v7nh2, d1v7ni2, d1v7nj2, d1v7nk2, d1v7nl1, d1v7nl2, d1v7nm1, d1v7nm2, d1v7nn1, d1v7nn2, d1v7no1, d1v7no2, d1v7nv_, d1v7nx_, d1v7ny_, d1v7nz_ part of anti-trombopoetin Fab tn1 |
Domain d1v7nk1: 1v7n K:1-116 [100466] Other proteins in same PDB: d1v7nh2, d1v7ni2, d1v7nj2, d1v7nk2, d1v7nl1, d1v7nl2, d1v7nm1, d1v7nm2, d1v7nn1, d1v7nn2, d1v7no1, d1v7no2, d1v7nv_, d1v7nx_, d1v7ny_, d1v7nz_ part of anti-trombopoetin Fab tn1 |
Domain d1wc7b1: 1wc7 B:1-113 [144550] Other proteins in same PDB: d1wc7a1, d1wc7a2, d1wc7b2, d1wc7h2, d1wc7l1, d1wc7l2 complexed with iod, pp3 |
Domain d1wc7h1: 1wc7 H:1-113 [144552] Other proteins in same PDB: d1wc7a1, d1wc7a2, d1wc7b2, d1wc7h2, d1wc7l1, d1wc7l2 automated match to d1wc7b1 complexed with iod, pp3 |
Domain d1wcbb1: 1wcb B:1-113 [144554] Other proteins in same PDB: d1wcba1, d1wcba2, d1wcbb2, d1wcbh2, d1wcbl1, d1wcbl2 automated match to d1wc7b1 complexed with iod, pe1 |
Domain d1wcbh1: 1wcb H:1-113 [144556] Other proteins in same PDB: d1wcba1, d1wcba2, d1wcbb2, d1wcbh2, d1wcbl1, d1wcbl2 automated match to d1wc7b1 complexed with iod, pe1 |
Domain d2a6db3: 2a6d B:1-121 [262186] Other proteins in same PDB: d2a6db2, d2a6dh2 |
Domain d2a6dh3: 2a6d H:1-121 [262188] Other proteins in same PDB: d2a6db2, d2a6dh2 |
Domain d2a6ib3: 2a6i B:1-121 [262190] Other proteins in same PDB: d2a6ib2 |
Domain d2a6kb3: 2a6k B:1-121 [262196] Other proteins in same PDB: d2a6kb2, d2a6kh2 |
Domain d2a6kh3: 2a6k H:1-121 [262198] Other proteins in same PDB: d2a6kb2, d2a6kh2 |
Domain d2bmkb1: 2bmk B:1-113 [144992] Other proteins in same PDB: d2bmka1, d2bmka2, d2bmkb2, d2bmkh2, d2bmkl1, d2bmkl2 automated match to d1wc7b1 complexed with iod, pdd |
Domain d2bmkh1: 2bmk H:1-113 [144994] Other proteins in same PDB: d2bmka1, d2bmka2, d2bmkb2, d2bmkh2, d2bmkl1, d2bmkl2 automated match to d1wc7b1 complexed with iod, pdd |
Domain d2cjvh_: 2cjv H: [303660] Other proteins in same PDB: d2cjvk_, d2cjvl_ automated match to d2uudh1 complexed with phx |
Domain d2cjvj_: 2cjv J: [303661] Other proteins in same PDB: d2cjvk_, d2cjvl_ automated match to d2uudh1 complexed with phx |
Domain d2ck0h1: 2ck0 H:6-117 [100853] Other proteins in same PDB: d2ck0h2, d2ck0h3, d2ck0l1, d2ck0l2 part of anti-anti-idiotypic Fab against human angiotensin II, complex with a synthetic cyclic peptide |
Domain d2dlfh_: 2dlf H: [20385] Other proteins in same PDB: d2dlfl_ part of anti-dansyl Fv complexed with so4 |
Domain d2g60h3: 2g60 H:1-113 [262204] Other proteins in same PDB: d2g60h2, d2g60l1, d2g60l2 |
Domain d2mcph1: 2mcp H:1-121 [19861] Other proteins in same PDB: d2mcph2, d2mcpl1, d2mcpl2 part of Fab MCPC603 complexed with pc |
Domain d2r1wb1: 2r1w B:1-111 [205928] Other proteins in same PDB: d2r1wa1, d2r1wa2, d2r1wb2 automated match to d3t65b1 complexed with mg, zn |
Domain d2r1xb1: 2r1x B:1-111 [205932] Other proteins in same PDB: d2r1xa1, d2r1xa2, d2r1xb2 automated match to d3t65b1 complexed with mg, zn |
Domain d2r1yb1: 2r1y B:1-111 [205936] Other proteins in same PDB: d2r1ya1, d2r1ya2, d2r1yb2 automated match to d3t65b1 complexed with mg, zn |
Domain d2r23b1: 2r23 B:1-111 [205940] Other proteins in same PDB: d2r23a1, d2r23a2, d2r23b2 automated match to d3t77b1 complexed with mg, zn |
Domain d2r2bb1: 2r2b B:1-111 [205944] Other proteins in same PDB: d2r2ba1, d2r2ba2, d2r2bb2 automated match to d3t65b1 complexed with zn |
Domain d2r2eb1: 2r2e B:1-111 [205948] Other proteins in same PDB: d2r2ea1, d2r2ea2, d2r2eb2 automated match to d3t65b1 complexed with kde |
Domain d2r2hb1: 2r2h B:1-111 [205952] Other proteins in same PDB: d2r2ha1, d2r2ha2, d2r2hb2 automated match to d3t65b1 complexed with ko2, mg, zn |
Domain d2uudh1: 2uud H:1-113 [152181] Other proteins in same PDB: d2uudk_, d2uudl_ complexed with phx |
Domain d2uudj1: 2uud J:1-113 [152182] Other proteins in same PDB: d2uudk_, d2uudl_ complexed with phx |
Domain d2zkhh1: 2zkh H:1-116 [207868] Other proteins in same PDB: d2zkhh2, d2zkhl1, d2zkhl2 automated match to d1v7mh1 |
Domain d3bpcb1: 3bpc B:1-111 [208688] Other proteins in same PDB: d3bpca1, d3bpca2, d3bpcb2 automated match to d3t65b1 complexed with mg, zn |
Domain d3ck0h1: 3ck0 H:6-117 [100865] Other proteins in same PDB: d3ck0h2, d3ck0h3, d3ck0l1, d3ck0l2 part of anti-anti-idiotypic Fab against human angiotensin II, complex with angiotensin II |
Domain d3fo9b1: 3fo9 B:1-113 [210028] Other proteins in same PDB: d3fo9a1, d3fo9a2, d3fo9b2, d3fo9h2, d3fo9l1, d3fo9l2 automated match to d1axth1 complexed with dik |
Domain d3fo9h1: 3fo9 H:1-113 [210030] Other proteins in same PDB: d3fo9a1, d3fo9a2, d3fo9b2, d3fo9h2, d3fo9l1, d3fo9l2 automated match to d1axth1 complexed with dik |
Domain d3sy0b1: 3sy0 B:1-111 [185583] Other proteins in same PDB: d3sy0a1, d3sy0a2, d3sy0b2 part of Fab s25-2 complexed with mg, zn |
Domain d3t4yb1: 3t4y B:1-111 [185646] Other proteins in same PDB: d3t4ya1, d3t4ya2, d3t4yb2 part of Fab s25-2 complexed with kdo, mg, zn |
Domain d3t65b1: 3t65 B:1-111 [185656] Other proteins in same PDB: d3t65a1, d3t65a2, d3t65b2 part of Fab s25-2 complexed with mg, zn |
Domain d3t77b1: 3t77 B:1-111 [185669] Other proteins in same PDB: d3t77a1, d3t77a2, d3t77b2 part of Fab s25-2 complexed with mg, zn |
Domain d4fabh1: 4fab H:1-118 [19907] Other proteins in same PDB: d4fabh2, d4fabl1, d4fabl2 part of Fab 4-4-20 complexed with flu, mpd |
Domain d4hgwb1: 4hgw B:1-112 [222600] Other proteins in same PDB: d4hgwa1, d4hgwa2, d4hgwb2 automated match to d3t65b1 complexed with zn |
Timeline for Species Mouse (Mus musculus), cluster 1 [TaxId:10090] from b.1.1.1 Immunoglobulin heavy chain variable domain, VH: